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{{Growth hormone deficiency}} | {{Growth hormone deficiency}} | ||
{{CMG}} | {{CMG}} | ||
==Overview== | ==Overview== | ||
The diagnosis of growth hormone deficiency is based on the direct hormonal criteria, indirect hormonal criteria and radiological evidence of response to GH treatment. | |||
==Diagnostic Criteria== | ==Diagnostic Criteria== | ||
* Diagnosis of growth hormone deficiency is a subject of debate due to high costs and complexity of investigations. | * Diagnosis of growth hormone deficiency is a subject of debate due to high costs and complexity of investigations. | ||
* Several types of evidence are used to diagnose GH deficiency: | * Several types of evidence are used to diagnose GH deficiency: | ||
**Body measurements. GH deficiency accounts for only a minority of [[short stature]] among children. | |||
* Body measurements. GH deficiency accounts for only a minority of [[short stature]] among children. | **Indirect [[hormonal]] criteria ([[IGF]] levels) | ||
* Indirect [[hormonal]] criteria ([[IGF]] levels) | **Direct [[hormonal]] criteria (secretory patterns of [[Growth hormone|GH levels]] or responses to [[Growth hormone|GH]] stimulation tests) | ||
* Direct [[hormonal]] criteria (secretory patterns of [[Growth hormone|GH levels]] or responses to [[Growth hormone|GH]] stimulation tests) | **Response to [[Growth hormone|GH treatment]] | ||
* Response to [[Growth hormone|GH treatment]] | **Radiological evidence of [[Pituitary disease|pituitary dysfunction]] | ||
* Radiological evidence of [[Pituitary disease|pituitary dysfunction]] | |||
* Many children and adults may not meet all the diagnostic criteria. | * Many children and adults may not meet all the diagnostic criteria. | ||
* An ideal [[diagnostic test]] cleanly separates people who would benefit from a treatment from those who would not. | * An ideal [[diagnostic test]] cleanly separates people who would benefit from a treatment from those who would not. | ||
Latest revision as of 22:08, 11 October 2017
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Growth hormone deficiency Microchapters |
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Differentiating Growth hormone deficiency from other Diseases |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
The diagnosis of growth hormone deficiency is based on the direct hormonal criteria, indirect hormonal criteria and radiological evidence of response to GH treatment.
Diagnostic Criteria
- Diagnosis of growth hormone deficiency is a subject of debate due to high costs and complexity of investigations.
- Several types of evidence are used to diagnose GH deficiency:
- Body measurements. GH deficiency accounts for only a minority of short stature among children.
- Indirect hormonal criteria (IGF levels)
- Direct hormonal criteria (secretory patterns of GH levels or responses to GH stimulation tests)
- Response to GH treatment
- Radiological evidence of pituitary dysfunction
- Many children and adults may not meet all the diagnostic criteria.
- An ideal diagnostic test cleanly separates people who would benefit from a treatment from those who would not.