Bone or cartilage mass biopsy: Difference between revisions
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==Overview== | ==Overview== | ||
Bone biopsy findings associated with bone and cartilage tumors will depend on tumor histology, common findings include: anastomosing bony trabeculae, calcifications surrounded by cells nests, and increased/decreased osteoblasts and osteoclasts.<ref name="pmid16951637">{{cite journal |vauthors=Mankin HJ, Lange TA, Spanier SS |title=THE CLASSIC: The hazards of biopsy in patients with malignant primary bone and soft-tissue tumors. The Journal of Bone and Joint Surgery, 1982;64:1121-1127 |journal=Clin. Orthop. Relat. Res. |volume=450 |issue= |pages=4–10 |year=2006 |pmid=16951637 |doi=10.1097/01.blo.0000229299.36969.b5 |url=}}</ref> | Bone biopsy findings associated with bone and cartilage tumors will depend on tumor [[histology]], common findings include: anastomosing bony trabeculae, calcifications surrounded by cells nests, and increased/decreased [[osteoblasts]] and [[osteoclasts]].<ref name="pmid16951637">{{cite journal |vauthors=Mankin HJ, Lange TA, Spanier SS |title=THE CLASSIC: The hazards of biopsy in patients with malignant primary bone and soft-tissue tumors. The Journal of Bone and Joint Surgery, 1982;64:1121-1127 |journal=Clin. Orthop. Relat. Res. |volume=450 |issue= |pages=4–10 |year=2006 |pmid=16951637 |doi=10.1097/01.blo.0000229299.36969.b5 |url=}}</ref> | ||
==Biopsy== | ==Biopsy== | ||
Common types of bone biopsy, include:<ref name="pmid16951637">{{cite journal |vauthors=Mankin HJ, Lange TA, Spanier SS |title=THE CLASSIC: The hazards of biopsy in patients with malignant primary bone and soft-tissue tumors. The Journal of Bone and Joint Surgery, 1982;64:1121-1127 |journal=Clin. Orthop. Relat. Res. |volume=450 |issue= |pages=4–10 |year=2006 |pmid=16951637 |doi=10.1097/01.blo.0000229299.36969.b5 |url=}}</ref><ref name="pmid12034942">{{cite journal |vauthors=Jelinek JS, Murphey MD, Welker JA, Henshaw RM, Kransdorf MJ, Shmookler BM, Malawer MM |title=Diagnosis of primary bone tumors with image-guided percutaneous biopsy: experience with 110 tumors |journal=Radiology |volume=223 |issue=3 |pages=731–7 |year=2002 |pmid=12034942 |doi=10.1148/radiol.2233011050 |url=}}</ref> | |||
Common types of bone biopsy, include:<ref name="pmid16951637">{{cite journal |vauthors=Mankin HJ, Lange TA, Spanier SS |title=THE CLASSIC: The hazards of biopsy in patients with malignant primary bone and soft-tissue tumors. The Journal of Bone and Joint Surgery, 1982;64:1121-1127 |journal=Clin. Orthop. Relat. Res. |volume=450 |issue= |pages=4–10 |year=2006 |pmid=16951637 |doi=10.1097/01.blo.0000229299.36969.b5 |url=}}</ref> | |||
*'''Open''' | *'''Open''' | ||
:*Performed during surgery | :*Performed during surgery | ||
:*On malignant lesions, biopsy incisions are: longitudinal, small, | :*Diagnostic accuracy is similar to closed biopsy. | ||
:*On malignant lesions, biopsy incisions are: longitudinal, small, or anatomically placed to minimize contamination of normal tissue | |||
:*Increased risk of complications | :*Increased risk of complications | ||
:*Tissue biopsy analyzed for bacterial and fungal culture, because bone infections may mimic a bone tumor | :*Tissue biopsy analyzed for bacterial and fungal culture, because bone infections may mimic a bone tumor | ||
*'''Closed''' | *'''Closed''' | ||
:*Initial biopsy in most bone and cartilage tumors. | |||
:*Less invasive and lower risk of tissue contamination with tumor cells | :*Less invasive and lower risk of tissue contamination with tumor cells | ||
:*Usually involves CT | :*Usually involves CT image-guided percutaneous biopsy | ||
:*Less risk of complications | :*Less risk of complications | ||
:*Biopsy in tumors that are predominantly cystic or with fluid levels (likely to result in nondiagnostic results) | |||
:*Less painful, and less costly | :*Less painful, and less costly | ||
:*Disadvantages, include: insufficient tissue from lesions and erroneous diagnosis of tumor grade | :*Disadvantages, include: insufficient tissue from lesions and erroneous diagnosis of tumor grade | ||
*Common bone and cartilage tumors biopsy findings, include: | |||
:*Anastomosing bony trabeculae | |||
:*Calcifications surrounded by cells nests | |||
:*Increased/decreased osteoblasts and osteoclasts | |||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
[[Category:Up-To-Date]] | |||
[[Category:Oncology]] | |||
[[Category:Medicine]] | |||
[[Category:Rheumatology]] | |||
[[Category:Orthopedics]] | |||
Latest revision as of 02:31, 6 November 2017
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Bone or Cartilage Mass Microchapters |
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Bone or cartilage mass biopsy On the Web |
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American Roentgen Ray Society Images of Bone or cartilage mass biopsy |
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Risk calculators and risk factors for Bone or cartilage mass biopsy |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Maria Fernanda Villarreal, M.D. [2]
Overview
Bone biopsy findings associated with bone and cartilage tumors will depend on tumor histology, common findings include: anastomosing bony trabeculae, calcifications surrounded by cells nests, and increased/decreased osteoblasts and osteoclasts.[1]
Biopsy
Common types of bone biopsy, include:[1][2]
- Open
- Performed during surgery
- Diagnostic accuracy is similar to closed biopsy.
- On malignant lesions, biopsy incisions are: longitudinal, small, or anatomically placed to minimize contamination of normal tissue
- Increased risk of complications
- Tissue biopsy analyzed for bacterial and fungal culture, because bone infections may mimic a bone tumor
- Closed
- Initial biopsy in most bone and cartilage tumors.
- Less invasive and lower risk of tissue contamination with tumor cells
- Usually involves CT image-guided percutaneous biopsy
- Less risk of complications
- Biopsy in tumors that are predominantly cystic or with fluid levels (likely to result in nondiagnostic results)
- Less painful, and less costly
- Disadvantages, include: insufficient tissue from lesions and erroneous diagnosis of tumor grade
- Common bone and cartilage tumors biopsy findings, include:
- Anastomosing bony trabeculae
- Calcifications surrounded by cells nests
- Increased/decreased osteoblasts and osteoclasts
References
- ↑ 1.0 1.1 Mankin HJ, Lange TA, Spanier SS (2006). "THE CLASSIC: The hazards of biopsy in patients with malignant primary bone and soft-tissue tumors. The Journal of Bone and Joint Surgery, 1982;64:1121-1127". Clin. Orthop. Relat. Res. 450: 4–10. doi:10.1097/01.blo.0000229299.36969.b5. PMID 16951637.
- ↑ Jelinek JS, Murphey MD, Welker JA, Henshaw RM, Kransdorf MJ, Shmookler BM, Malawer MM (2002). "Diagnosis of primary bone tumors with image-guided percutaneous biopsy: experience with 110 tumors". Radiology. 223 (3): 731–7. doi:10.1148/radiol.2233011050. PMID 12034942.