Hepatoblastoma risk factors: Difference between revisions
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{{CMG}};{{AE}} {{NM}} | {{CMG}};{{AE}} {{NM}} | ||
==Overview== | ==Overview== | ||
Common risk factors in the development of hepatoblastoma are [[Aicardi syndrome]], [[Beckwith-Wiedemann syndrome]], [[familial adenomatous polyposis]], [[low birth weight|low birth weight infants]], and [[glycogen storage diseases]].<ref name=risk>Risk factors. National Cancer Institute 2015. http://www.cancer.gov/types/liver/hp/child-liver-treatment-pdq#link/_570_toc. Accessed on October 28, 2015</ref> | |||
==Risk Factors== | ==Risk Factors== | ||
The table below lists risk factors for hepatoblastoma:<ref name=risk>Risk factors. National Cancer Institute 2015. http://www.cancer.gov/types/liver/hp/child-liver-treatment-pdq#link/_570_toc. Accessed on October 28, 2015</ref> | The table below lists risk factors for hepatoblastoma:<ref name=risk>Risk factors. National Cancer Institute 2015. http://www.cancer.gov/types/liver/hp/child-liver-treatment-pdq#link/_570_toc. Accessed on October 28, 2015</ref> | ||
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| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center | '''[[Aicardi syndrome]]'''|| style="padding: 5px 5px; background: #F5F5F5;" | | | style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center | '''[[Aicardi syndrome]]'''|| style="padding: 5px 5px; background: #F5F5F5;" | | ||
:* Agenesis of the corpus callosum, chorioretinal lacunae, and infantile spasms, with a characteristic facies | :* Agenesis of the corpus callosum, chorioretinal lacunae, and [[infantile spasms]], with a characteristic facies | ||
|- | |- | ||
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center | '''[[Beckwith-Wiedemann syndrome]]'''|| style="padding: 5px 5px; background: #F5F5F5;"| | | style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center | '''[[Beckwith-Wiedemann syndrome]]'''|| style="padding: 5px 5px; background: #F5F5F5;"| | ||
:* Hemihypertrophy, hemihyperplasia | :* [[Hemihypertrophy]], hemihyperplasia | ||
|- | |- | ||
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center | '''[[Familial adenomatous polyposis]]'''|| style="padding: 5px 5px; background: #F5F5F5;"| | | style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center | '''[[Familial adenomatous polyposis]]'''|| style="padding: 5px 5px; background: #F5F5F5;"| | ||
:* | :*Adenoma, hepatoblastoma | ||
|- | |- | ||
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center | '''[[Glycogen storage diseases]] I–IV '''|| style="padding: 5px 5px; background: #F5F5F5;" | | | style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center | '''[[Glycogen storage diseases]] I–IV '''|| style="padding: 5px 5px; background: #F5F5F5;" | | ||
:*Symptoms vary by individual disorder | :*Symptoms vary by individual disorder | ||
|- | |- | ||
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center | '''Low | | style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center | '''[[low birth weight|Low birth weight infants]]'''|| style="padding: 5px 5px; background: #F5F5F5;" | | ||
:*Preterm and small-for-gestation-age neonates | :*Preterm and small-for-gestation-age neonates | ||
|- | |- | ||
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center | '''[[Simpson-Golabi-Behmel syndrome]]'''|| style="padding: 5px 5px; background: #F5F5F5;"| | | style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center | '''[[Simpson-Golabi-Behmel syndrome]]'''|| style="padding: 5px 5px; background: #F5F5F5;"| | ||
:*Macroglossia, macrosomia, renal and skeletal abnormalities, and increased risk of [[Wilms tumor]] | :*[[Macroglossia]], [[macrosomia]], renal and skeletal abnormalities, and increased risk of [[Wilms tumor]] | ||
|- | |- | ||
|style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center | '''[[Trisomy 18]], other trisomies'''|| style="padding: 5px 5px; background: #F5F5F5;" | | |style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center | '''[[Trisomy 18]], other trisomies'''|| style="padding: 5px 5px; background: #F5F5F5;" | | ||
:*[[Trisomy 18]]: [[Microcephaly]] and [[micrognathia]], clenched fists with overlapping fingers, and failure to thrive | :*[[Trisomy 18]]: [[Microcephaly]] and [[micrognathia]], clenched fists with overlapping fingers, and [[failure to thrive]] | ||
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[[Category:Hepatology]] |
Latest revision as of 01:58, 27 November 2017
Hepatoblastoma Microchapters |
Diagnosis |
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Treatment |
Case Studies |
Hepatoblastoma risk factors On the Web |
American Roentgen Ray Society Images of Hepatoblastoma risk factors |
Risk calculators and risk factors for Hepatoblastoma risk factors |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Nawal Muazam M.D.[2]
Overview
Common risk factors in the development of hepatoblastoma are Aicardi syndrome, Beckwith-Wiedemann syndrome, familial adenomatous polyposis, low birth weight infants, and glycogen storage diseases.[1]
Risk Factors
The table below lists risk factors for hepatoblastoma:[1]
Associated Disorder | Clinical findings |
---|---|
Aicardi syndrome |
|
Beckwith-Wiedemann syndrome |
|
Familial adenomatous polyposis |
|
Glycogen storage diseases I–IV |
|
Low birth weight infants |
|
Simpson-Golabi-Behmel syndrome |
|
Trisomy 18, other trisomies |
|
References
- ↑ 1.0 1.1 Risk factors. National Cancer Institute 2015. http://www.cancer.gov/types/liver/hp/child-liver-treatment-pdq#link/_570_toc. Accessed on October 28, 2015