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<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{Infobox_gene}}
{{PBB_Controls
'''Olfactory receptor 51B2''' is a [[protein]] that in humans is encoded by the ''OR51B2'' [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: OR51B2 olfactory receptor, family 51, subfamily B, member 2| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=79345| accessdate = }}</ref>
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}


<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
== Function ==
{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = Olfactory receptor, family 51, subfamily B, member 2
| HGNCid = 14703
| Symbol = OR51B2
| AltSymbols =; HOR5'Beta3; OR51B1P
| OMIM = 
| ECnumber = 
| Homologene = 56593
| MGIid = 1341900
| Function = {{GNF_GO|id=GO:0004872 |text = receptor activity}} {{GNF_GO|id=GO:0004984 |text = olfactory receptor activity}}
| Component = {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}}
| Process = {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007186 |text = G-protein coupled receptor protein signaling pathway}} {{GNF_GO|id=GO:0007608 |text = sensory perception of smell}} {{GNF_GO|id=GO:0050896 |text = response to stimulus}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 79345
    | Hs_Ensembl = ENSG00000184881
    | Hs_RefseqProtein = NP_149420
    | Hs_RefseqmRNA = NM_033180
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 11
    | Hs_GenLoc_start = 5301165
    | Hs_GenLoc_end = 5302103
    | Hs_Uniprot = Q9Y5P1
    | Mm_EntrezGene = 18366
    | Mm_Ensembl = ENSMUSG00000063615
    | Mm_RefseqmRNA = NM_013617
    | Mm_RefseqProtein = NP_038645
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 7
    | Mm_GenLoc_start = 103766631
    | Mm_GenLoc_end = 103767563
    | Mm_Uniprot = 
  }}
}}
'''Olfactory receptor, family 51, subfamily B, member 2''', also known as '''OR51B2''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: OR51B2 olfactory receptor, family 51, subfamily B, member 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=79345| accessdate = }}</ref>


<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.<ref name="entrez" />
{{PBB_Summary
| section_title =
| summary_text = Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.<ref name="entrez">{{cite web | title = Entrez Gene: OR51B2 olfactory receptor, family 51, subfamily B, member 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=79345| accessdate = }}</ref>
}}


==See also==
== See also ==
* [[Olfactory receptor]]
* [[Olfactory receptor]]


==References==
== References ==
{{reflist|2}}
{{reflist}}


==Further reading==
== Further reading ==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading
* {{cite journal | vauthors = Bulger M, van Doorninck JH, Saitoh N, Telling A, Farrell C, Bender MA, Felsenfeld G, Axel R, Groudine M, von Doorninck JH | title = Conservation of sequence and structure flanking the mouse and human beta-globin loci: the beta-globin genes are embedded within an array of odorant receptor genes | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 96 | issue = 9 | pages = 5129–34 | date = April 1999 | pmid = 10220430 | pmc = 21828 | doi = 10.1073/pnas.96.9.5129 }}
| citations =
* {{cite journal | vauthors = Bulger M, Bender MA, van Doorninck JH, Wertman B, Farrell CM, Felsenfeld G, Groudine M, Hardison R | title = Comparative structural and functional analysis of the olfactory receptor genes flanking the human and mouse beta-globin gene clusters | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 97 | issue = 26 | pages = 14560–5 | date = December 2000 | pmid = 11121057 | pmc = 18958 | doi = 10.1073/pnas.97.26.14560 }}
*{{cite journal | author=Bulger M, van Doorninck JH, Saitoh N, ''et al.'' |title=Conservation of sequence and structure flanking the mouse and human beta-globin loci: the beta-globin genes are embedded within an array of odorant receptor genes. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=96 |issue= 9 |pages= 5129-34 |year= 1999 |pmid= 10220430 |doi= }}
* {{cite journal | vauthors = Fuchs T, Malecova B, Linhart C, Sharan R, Khen M, Herwig R, Shmulevich D, Elkon R, Steinfath M, O'Brien JK, Radelof U, Lehrach H, Lancet D, Shamir R | title = DEFOG: a practical scheme for deciphering families of genes | journal = Genomics | volume = 80 | issue = 3 | pages = 295–302 | date = September 2002 | pmid = 12213199 | doi = 10.1006/geno.2002.6830 }}
*{{cite journal | author=Bulger M, Bender MA, van Doorninck JH, ''et al.'' |title=Comparative structural and functional analysis of the olfactory receptor genes flanking the human and mouse beta-globin gene clusters. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=97 |issue= 26 |pages= 14560-5 |year= 2001 |pmid= 11121057 |doi= 10.1073/pnas.97.26.14560 }}
*{{cite journal | author=Fuchs T, Malecova B, Linhart C, ''et al.'' |title=DEFOG: a practical scheme for deciphering families of genes. |journal=Genomics |volume=80 |issue= 3 |pages= 295-302 |year= 2003 |pmid= 12213199 |doi=  }}
*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
}}
{{refend}}
{{refend}}


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{{NLM content}}
{{NLM content}}
{{membrane-protein-stub}}
{{transmembranereceptor-stub}}
{{Olfactory receptors}}
{{Olfactory receptors}}
[[Category:G protein coupled receptors]]
[[Category:Olfactory receptors]]
{{WikiDoc Sources}}

Latest revision as of 02:35, 27 October 2017

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Olfactory receptor 51B2 is a protein that in humans is encoded by the OR51B2 gene.[1]

Function

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[1]

See also

References

  1. ↑ 1.0 1.1 "Entrez Gene: OR51B2 olfactory receptor, family 51, subfamily B, member 2".

Further reading

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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