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'''Olfactory receptor 7A5''' is a [[protein]] that in humans is encoded by the ''OR7A5'' [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: OR7A5 olfactory receptor, family 7, subfamily A, member 5| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=26659| accessdate = }}</ref> | |||
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'''Olfactory receptor | |||
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| summary_text = Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.<ref name="entrez" | | summary_text = Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.<ref name="entrez" /> | ||
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==References== | ==References== | ||
{{reflist | {{reflist}} | ||
==Further reading== | ==Further reading== | ||
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*{{cite journal | author=Gerhard DS | *{{cite journal | author=Gerhard DS |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–2127 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 |name-list-format=vanc| author2=Wagner L | author3=Feingold EA | display-authors=3 | last4=Shenmen | first4=CM | last5=Grouse | first5=LH | last6=Schuler | first6=G | last7=Klein | first7=SL | last8=Old | first8=S | last9=Rasooly | first9=R }} | ||
*{{cite journal | author=Grimwood J | *{{cite journal | author=Grimwood J |title=The DNA sequence and biology of human chromosome 19 |journal=Nature |volume=428 |issue= 6982 |pages= 529–535 |year= 2004 |pmid= 15057824 |doi= 10.1038/nature02399 |name-list-format=vanc| author2=Gordon LA | author3=Olsen A | display-authors=3 | last4=Terry | first4=Astrid | last5=Schmutz | first5=Jeremy | last6=Lamerdin | first6=Jane | last7=Hellsten | first7=Uffe | last8=Goodstein | first8=David | last9=Couronne | first9=Olivier }} | ||
*{{cite journal | | *{{cite journal |vauthors=Malnic B, Godfrey PA, Buck LB |title=The human olfactory receptor gene family |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 8 |pages= 2584–2589 |year= 2004 |pmid= 14983052 |doi=10.1073/pnas.0307882100 | pmc=356993 }} | ||
*{{cite journal | author=Strausberg RL | *{{cite journal | author=Strausberg RL |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–16903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |name-list-format=vanc| author2=Feingold EA | author3=Grouse LH | display-authors=3 | last4=Derge | first4=JG | last5=Klausner | first5=RD | last6=Collins | first6=FS | last7=Wagner | first7=L | last8=Shenmen | first8=CM | last9=Schuler | first9=GD }} | ||
*{{cite journal | author=Fuchs T | *{{cite journal | author=Fuchs T |title=DEFOG: a practical scheme for deciphering families of genes |journal=Genomics |volume=80 |issue= 3 |pages= 295–302 |year= 2003 |pmid= 12213199 |doi=10.1006/geno.2002.6830 |name-list-format=vanc| author2=Malecova B | author3=Linhart C | display-authors=3 | last4=Sharan | first4=Roded | last5=Khen | first5=Miriam | last6=Herwig | first6=Ralf | last7=Shmulevich | first7=Dmitry | last8=Elkon | first8=Rani | last9=Steinfath | first9=Matthias }} | ||
*{{cite journal | | *{{cite journal |vauthors=Vanderhaeghen P, Schurmans S, Vassart G, Parmentier M |title=Molecular cloning and chromosomal mapping of olfactory receptor genes expressed in the male germ line: evidence for their wide distribution in the human genome |journal=Biochem. Biophys. Res. Commun. |volume=237 |issue= 2 |pages= 283–287 |year= 1997 |pmid= 9268701 |doi= 10.1006/bbrc.1997.7043 }} | ||
*{{cite journal | | *{{cite journal |vauthors=Vanderhaeghen P, Schurmans S, Vassart G, Parmentier M |title=Specific repertoire of olfactory receptor genes in the male germ cells of several mammalian species |journal=Genomics |volume=39 |issue= 3 |pages= 239–246 |year= 1997 |pmid= 9119360 |doi= 10.1006/geno.1996.4490 }} | ||
*{{cite journal | author=Parmentier M | *{{cite journal | author=Parmentier M |title=Expression of members of the putative olfactory receptor gene family in mammalian germ cells |journal=Nature |volume=355 |issue= 6359 |pages= 453–455 |year= 1992 |pmid= 1370859 |doi= 10.1038/355453a0 |name-list-format=vanc| author2=Libert F | author3=Schurmans S | display-authors=3 | last4=Schiffmann | first4=Serge | last5=Lefort | first5=Anne | last6=Eggerickx | first6=Dominique | last7=Ledent | first7=Catherine | last8=Mollereau | first8=Catherine | last9=Gérard | first9=Catherine }} | ||
}} | }} | ||
{{refend}} | {{refend}} | ||
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{{NLM content}} | {{NLM content}} | ||
{{Olfactory receptors}} | {{Olfactory receptors}} | ||
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Latest revision as of 00:32, 7 September 2017
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Olfactory receptor 7A5 is a protein that in humans is encoded by the OR7A5 gene.[1]
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[1]
See also
References
Further reading
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–2127. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Grimwood J, Gordon LA, Olsen A, et al. (2004). "The DNA sequence and biology of human chromosome 19". Nature. 428 (6982): 529–535. doi:10.1038/nature02399. PMID 15057824.
- Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–2589. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–16903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID 12213199.
- Vanderhaeghen P, Schurmans S, Vassart G, Parmentier M (1997). "Molecular cloning and chromosomal mapping of olfactory receptor genes expressed in the male germ line: evidence for their wide distribution in the human genome". Biochem. Biophys. Res. Commun. 237 (2): 283–287. doi:10.1006/bbrc.1997.7043. PMID 9268701.
- Vanderhaeghen P, Schurmans S, Vassart G, Parmentier M (1997). "Specific repertoire of olfactory receptor genes in the male germ cells of several mammalian species". Genomics. 39 (3): 239–246. doi:10.1006/geno.1996.4490. PMID 9119360.
- Parmentier M, Libert F, Schurmans S, et al. (1992). "Expression of members of the putative olfactory receptor gene family in mammalian germ cells". Nature. 355 (6359): 453–455. doi:10.1038/355453a0. PMID 1370859.
External links
- OR7A5+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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