Odynophagia laboratory findings: Difference between revisions
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__NOTOC__ | __NOTOC__ | ||
{{Odynophagia}} | {{Odynophagia}} | ||
{{CMG}} | {{CMG}} {{AE}} {{SKA}} | ||
== Overview: == | |||
Patient with odynophagia will need [[Blood chemistry tests|blood chemistry]] and [[cytology]] according to the supporting history and examination to rule out causes of pain in swallowing. | |||
== Laboratory Findings == | |||
Following are relevant laboratory investigations to approach a case of odynophagia:<ref name="pmid29264291">{{cite journal| author=Jalisi S, Jamal BT, Grillone GA| title=Surgical Management of Long-standing Eagle's Syndrome. | journal=Ann Maxillofac Surg | year= 2017 | volume= 7 | issue= 2 | pages= 232-236 | pmid=29264291 | doi=10.4103/ams.ams_53_17 | pmc=5717900 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29264291 }}</ref><ref name="pmid29264290">{{cite journal| author=Jalisi S, Sakai O, Jamal BT, Mardirossian V| title=Features of Prevertebral Disease in Patients Presenting to a Head and Neck Surgery Clinic with Neck Pain. | journal=Ann Maxillofac Surg | year= 2017 | volume= 7 | issue= 2 | pages= 228-231 | pmid=29264290 | doi=10.4103/ams.ams_54_17 | pmc=5717899 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29264290 }}</ref><ref name="pmid29255766">{{cite journal| author=Marques S, Carmo J, Pinto D, Bispo M, Ramos S, Chagas C| title=Cytomegalovirus Disease of the Upper Gastrointestinal Tract: A 10-Year Retrospective Study. | journal=GE Port J Gastroenterol | year= 2017 | volume= 24 | issue= 6 | pages= 262-268 | pmid=29255766 | doi=10.1159/000479232 | pmc=5731150 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29255766 }}</ref><ref name="pmid29206327">{{cite journal| author=Rama-López J, Tomás-Fernandez M, García-Garza C, Martínez-Madrigal M| title=Pharyngeal perforation after anterior cervical spine surgery treated by transoral endoscopic surgery. | journal=Head Neck | year= 2018 | volume= 40 | issue= 2 | pages= E13-E16 | pmid=29206327 | doi=10.1002/hed.25030 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29206327 }}</ref><ref name="pmid29198289">{{cite journal| author=Kato MG, Isaac MJ, Gillespie MB, O'Rourke AK| title=The Incidence and Characterization of Globus Sensation, Dysphagia, and Odynophagia Following Surgery for Obstructive Sleep Apnea. | journal=J Clin Sleep Med | year= 2018 | volume= 14 | issue= 1 | pages= 127-132 | pmid=29198289 | doi=10.5664/jcsm.6898 | pmc=5734881 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29198289 }}</ref><ref name="pmid29168645">{{cite journal| author=Teixeira C, Alves AL, Cremers I| title=Esophageal lichen planus: a rare case. | journal=Rev Esp Enferm Dig | year= 2018 | volume= 110 | issue= 1 | pages= 67-68 | pmid=29168645 | doi=10.17235/reed.2017.5332/2017 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29168645 }}</ref><ref name="pmid29146495">{{cite journal| author=Chen L, Lai Y, Dong L, Kang S, Chen X| title=Polysaccharides from Citrus grandis L. Osbeck suppress inflammation and relieve chronic pharyngitis. | journal=Microb Pathog | year= 2017 | volume= 113 | issue= | pages= 365-371 | pmid=29146495 | doi=10.1016/j.micpath.2017.11.018 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29146495 }}</ref><ref name="pmid29145245">{{cite journal| author=Kim YJ, Park JY, Choi KY, Moon BJ, Lee JK| title=Case reports about an overlooked cause of neck pain: calcific tendinitis of the longus colli: Case reports. | journal=Medicine (Baltimore) | year= 2017 | volume= 96 | issue= 46 | pages= e8343 | pmid=29145245 | doi=10.1097/MD.0000000000008343 | pmc=5704790 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29145245 }}</ref><ref name="pmid29145108">{{cite journal| author=Alamoudi U, Al-Sayed AA, AlSallumi Y, Rigby MH, Taylor SM, Hart RD et al.| title=Acute calcific tendinitis of the longus colli muscle masquerading as a retropharyngeal abscess: A case report and review of the literature. | journal=Int J Surg Case Rep | year= 2017 | volume= 41 | issue= | pages= 343-346 | pmid=29145108 | doi=10.1016/j.ijscr.2017.10.063 | pmc=5686463 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29145108 }}</ref><ref name="pmid29128948">{{cite journal| author=Sopeña B, Limeres J, García-Caballero L, Diniz-Freitas M, Seoane J, Diz P| title=A Dramatic Case of Odynophagia. | journal=Dysphagia | year= 2018 | volume= 33 | issue= 1 | pages= 133-135 | pmid=29128948 | doi=10.1007/s00455-017-9861-8 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29128948 }}</ref><ref name="pmid29124648">{{cite journal| author=Fukuda S, Watanabe N, Domen T, Ishioka M, Sawaguchi M, Ohba R et al.| title=A case of esophageal actinomycosis with a unique morphology presenting as a refractory ulcer. | journal=Clin J Gastroenterol | year= 2018 | volume= 11 | issue= 1 | pages= 38-41 | pmid=29124648 | doi=10.1007/s12328-017-0797-1 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29124648 }}</ref><ref name="pmid29072250">{{cite journal| author=Chi TH, Hung CC, Chen RF, Yuan CH, Chen JC| title=Spontaneous retropharyngeal emphysema: A case report. | journal=Niger J Clin Pract | year= 2017 | volume= 20 | issue= 9 | pages= 1213-1215 | pmid=29072250 | doi=10.4103/njcp.njcp_3_16 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29072250 }}</ref><ref name="pmid29071486">{{cite journal| author=Jovov B, Reed CC, Shaheen NJ, Pruitt A, Ferrell K, Orlando GS et al.| title=Fragments of e-Cadherin as Biomarkers of Non-erosive Reflux Disease. | journal=Dig Dis Sci | year= 2017 | volume= | issue= | pages= | pmid=29071486 | doi=10.1007/s10620-017-4815-4 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29071486 }}</ref><ref name="pmid29043549">{{cite journal| author=Althuwaini S, Bamehriz F, Aldohayan A, Alshammari W, Alhaidar S, Alotaibi M et al.| title=Prevalence and Predictors of Gastroesophageal Reflux Disease After Laparoscopic Sleeve Gastrectomy. | journal=Obes Surg | year= 2017 | volume= | issue= | pages= | pmid=29043549 | doi=10.1007/s11695-017-2971-4 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29043549 }}</ref> | |||
====== Base Lines: ====== | |||
* [[Complete blood count|CBC]] | |||
* [[Erythrocyte sedimentation rate|ESR]] | |||
* [[C-reactive protein|CRP]] | |||
====== Specific tests ; ====== | |||
{| class="wikitable" | |||
|'''Cardiovascular''' | |||
| [[Mediastinitis]] | |||
|Fluid tap and C & S | |||
|- | |||
|'''Chemical / poisoning''' | |||
|[[Botulism]], [[Chemical burns]] | |||
|Toxicology and [[Botulism]] ELISA | |||
|- | |||
|'''Dermatologic''' | |||
|[[Scleroderma]] | |||
|Antitopoisomerase-1 or Anti-Scl-70 antibodies | |||
|- | |||
|'''Drug Side Effect''' | |||
|[[ibandronate]], [[Stevens-Johnson Syndrome]] | |||
|[[ANA]] profile and drug levels | |||
|- | |||
|'''Ear Nose Throat''' | |||
|[[Cricopharyngeal spasm]], [[Epiglottitis]], [[Glossitis]], [[Goiter]], [[Laryngitis]], [[Oral ulcers]] [[Stomatitis]], [[Herpangina]], [[Retropharyngeal abscess]] [[Xerostomia]] | |||
|[[Blood culture]], viral assay, throat culture, TSH | |||
|- | |||
|'''Endocrine''' | |||
|[[Diabetic neuropathy]], [[Hyperthyroidism]], [[Hypothyroidism]], [[Riedel thyroiditis]] | |||
|HBA1C, [[TSH]], [[Blood cultures]] | |||
|- | |||
|'''Gastroenterologic''' | |||
|[[Esophagitis]], [[Gastritis]], Intramural pseudodiverticulosis, [[Schatzki ring]], [[Myoneurogastrointestinal encephalopathy syndrome]], [[Crohn's disease]], [[Eosinophilic esophagitis]] | |||
|[[Electrolyte|Electrolytes]], [[Antinuclear antibodies|ANA profile]], stool H.pylori test | |||
|- | |||
|'''Genetic''' | |||
|[[Opitz-Frias syndrome]] | |||
|Genetic testing [[Polymerase chain reaction|PCR]] | |||
|- | |||
|'''Hematologic''' | |||
|[[Agranulocytosis]], [[Lymphadenopathy]] | |||
|[[Vitamin B12]], [[Red blood cell|RBC]] [[folate]], Bone marrow microscopy | |||
|- | |||
|'''Infectious Disease''' | |||
|[[Abscesses]], [[Acute pharyngitis]], [[Adenoiditis]], [[Candidiasis]], [[Chagas Disease]], [[Cytomegalovirus]], [[Diphtheria]], [[Esophageal moniliasis]], [[Flu]], [[Herpangina]], [[Herpes simplex virus (HSV)]], | |||
[[Herpes stomatitis]], [[HIV/AIDS]], [[Mononucleosis]], [[Mumps]], [[Oral candidiasis]], [[Paracoccidioidomycosis]], [[Pharyngitis]], [[Poliomyelitis]], [[Rabies]], [[Reflux esophagitis]], [[Respiratory tract infections]], | |||
[[Retropharyngeal abscess]], [[Scarlet Fever]], [[Tetanus]], [[Tonsillar abscess]], [[Typhoid fever]] | |||
|Viral markers, Blood C & S, | |||
Throat and sputum DR & CS, fungal markers | |||
|- | |||
|'''Musculoskeletal / Ortho''' | |||
|[[Schatzki ring]], [[Dermatomyositis]], [[Myasthenia Gravis]] | |||
|anti–acetylcholine receptor (AChR) antibody (Ab) | |||
Bone marrow microscopy, [[Creatine kinase|CK]], [[Aldolase]], | |||
Mi-2 (nuclear helicase protein) Antibody | |||
|- | |||
|'''Neurologic''' | |||
|[[Amyotrophic Lateral Sclerosis (ALS)]], [[Bulbar palsy]], [[Central hypoglossal nerve paralysis]], | |||
[[Central vagal nucleus lesion]], [[Cerebrovascular accident]], [[Guillain-Barre syndrome]], [[Huntington's chorea]], | |||
[[Multiple Sclerosis]], [[Myoneurogastrointestinal encephalopathy syndrome]], [[Neuroferritinopathy]], [[Peripheral neuropathy]], [[Polyradiculitis]], [[Diabetic neuropathy]], [[Poliomyelitis]] | |||
|[[anti-ganglioside antibodies]], anti GM1 antibodies and Anti-GQ1b,Stool culture for ''[[campylobacter jejuni]]'', trinucleotide repeat sequence "CAG", EMG, [[ANA]] | |||
|- | |||
|'''Nutritional / Metabolic''' | |||
|[[Gaucher's disease]], [[Plummer-Vinson Syndrome]] | |||
|Genetic testing, [[vitamin B12]], [[Red blood cell|RBC]], [[folate]], Bone marrow microscopy | |||
|- | |||
|'''Oncologic''' | |||
| [[Paraneoplastic syndrome]] | |||
|Hormone levels of [[calcium]], [[vitamin D]], [[Histamine]], IL-1 | |||
|- | |||
|'''Rheum / Immune / Allergy''' | |||
|[[Allergic swelling]], [[Amyloidosis]], [[Behcet's Syndrome]], [[CREST syndrome]] , [[Crohn's disease]], [[Dermatomyositis]], [[Eosinophilic esophagitis]], | |||
[[Esophageal sarcoidosis]], [[Graft versus host reaction]], [[Inclusion body myositis]], [[Myasthenia Gravis]], [[Parkinson's Disease]], [[Riedel thyroiditis]], | |||
[[Rheumatoid Arthritis]], [[Scleroderma]], [[Systemic Lupus Erythematosus]], [[Systemic sclerosis]], [[Xerostomia]] | |||
|[[Antinuclear antibodies|ANA]] profile, [[Rheumatoid factor|Rheumatoid factor,]] [[Bone marrow biopsy]], [[calcium]] level, [[vitamin D]] level, [[RNA polymerase]] types II and III ,RNP, Scl-70 , SS-A , SS-B | |||
|- | |||
|'''Sexual''' | |||
|Oral sex | |||
|Oral swab culture | |||
|- | |||
|'''Miscellaneous''' | |||
|[[Alcoholism]], [[Aspiration of foreign body]] | |||
|[[blood culture]], [[Blood alcohol content|blood alcohol levels]] | |||
|} | |||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
[[Category:Needs content]] | [[Category:Needs content]] | ||
[[Category:Gastroenterology]] | [[Category:Gastroenterology]] | ||
[[Category:Musculoskeletal Disease]] | [[Category:Musculoskeletal Disease]] | ||
{{WH}} | |||
{{WS}} | |||
Latest revision as of 15:31, 26 March 2018
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Odynophagia Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Odynophagia laboratory findings On the Web |
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American Roentgen Ray Society Images of Odynophagia laboratory findings |
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Risk calculators and risk factors for Odynophagia laboratory findings |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Sunny Kumar MD [2]
Overview:
Patient with odynophagia will need blood chemistry and cytology according to the supporting history and examination to rule out causes of pain in swallowing.
Laboratory Findings
Following are relevant laboratory investigations to approach a case of odynophagia:[1][2][3][4][5][6][7][8][9][10][11][12][13][14]
Base Lines:
Specific tests ;
References
- ↑ Jalisi S, Jamal BT, Grillone GA (2017). "Surgical Management of Long-standing Eagle's Syndrome". Ann Maxillofac Surg. 7 (2): 232–236. doi:10.4103/ams.ams_53_17. PMC 5717900. PMID 29264291.
- ↑ Jalisi S, Sakai O, Jamal BT, Mardirossian V (2017). "Features of Prevertebral Disease in Patients Presenting to a Head and Neck Surgery Clinic with Neck Pain". Ann Maxillofac Surg. 7 (2): 228–231. doi:10.4103/ams.ams_54_17. PMC 5717899. PMID 29264290.
- ↑ Marques S, Carmo J, Pinto D, Bispo M, Ramos S, Chagas C (2017). "Cytomegalovirus Disease of the Upper Gastrointestinal Tract: A 10-Year Retrospective Study". GE Port J Gastroenterol. 24 (6): 262–268. doi:10.1159/000479232. PMC 5731150. PMID 29255766.
- ↑ Rama-López J, Tomás-Fernandez M, García-Garza C, Martínez-Madrigal M (2018). "Pharyngeal perforation after anterior cervical spine surgery treated by transoral endoscopic surgery". Head Neck. 40 (2): E13–E16. doi:10.1002/hed.25030. PMID 29206327.
- ↑ Kato MG, Isaac MJ, Gillespie MB, O'Rourke AK (2018). "The Incidence and Characterization of Globus Sensation, Dysphagia, and Odynophagia Following Surgery for Obstructive Sleep Apnea". J Clin Sleep Med. 14 (1): 127–132. doi:10.5664/jcsm.6898. PMC 5734881. PMID 29198289.
- ↑ Teixeira C, Alves AL, Cremers I (2018). "Esophageal lichen planus: a rare case". Rev Esp Enferm Dig. 110 (1): 67–68. doi:10.17235/reed.2017.5332/2017. PMID 29168645.
- ↑ Chen L, Lai Y, Dong L, Kang S, Chen X (2017). "Polysaccharides from Citrus grandis L. Osbeck suppress inflammation and relieve chronic pharyngitis". Microb Pathog. 113: 365–371. doi:10.1016/j.micpath.2017.11.018. PMID 29146495.
- ↑ Kim YJ, Park JY, Choi KY, Moon BJ, Lee JK (2017). "Case reports about an overlooked cause of neck pain: calcific tendinitis of the longus colli: Case reports". Medicine (Baltimore). 96 (46): e8343. doi:10.1097/MD.0000000000008343. PMC 5704790. PMID 29145245.
- ↑ Alamoudi U, Al-Sayed AA, AlSallumi Y, Rigby MH, Taylor SM, Hart RD; et al. (2017). "Acute calcific tendinitis of the longus colli muscle masquerading as a retropharyngeal abscess: A case report and review of the literature". Int J Surg Case Rep. 41: 343–346. doi:10.1016/j.ijscr.2017.10.063. PMC 5686463. PMID 29145108.
- ↑ Sopeña B, Limeres J, García-Caballero L, Diniz-Freitas M, Seoane J, Diz P (2018). "A Dramatic Case of Odynophagia". Dysphagia. 33 (1): 133–135. doi:10.1007/s00455-017-9861-8. PMID 29128948.
- ↑ Fukuda S, Watanabe N, Domen T, Ishioka M, Sawaguchi M, Ohba R; et al. (2018). "A case of esophageal actinomycosis with a unique morphology presenting as a refractory ulcer". Clin J Gastroenterol. 11 (1): 38–41. doi:10.1007/s12328-017-0797-1. PMID 29124648.
- ↑ Chi TH, Hung CC, Chen RF, Yuan CH, Chen JC (2017). "Spontaneous retropharyngeal emphysema: A case report". Niger J Clin Pract. 20 (9): 1213–1215. doi:10.4103/njcp.njcp_3_16. PMID 29072250.
- ↑ Jovov B, Reed CC, Shaheen NJ, Pruitt A, Ferrell K, Orlando GS; et al. (2017). "Fragments of e-Cadherin as Biomarkers of Non-erosive Reflux Disease". Dig Dis Sci. doi:10.1007/s10620-017-4815-4. PMID 29071486.
- ↑ Althuwaini S, Bamehriz F, Aldohayan A, Alshammari W, Alhaidar S, Alotaibi M; et al. (2017). "Prevalence and Predictors of Gastroesophageal Reflux Disease After Laparoscopic Sleeve Gastrectomy". Obes Surg. doi:10.1007/s11695-017-2971-4. PMID 29043549.