Idiopathic pulmonary fibrosis surgery: Difference between revisions
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__NOTOC__ | __NOTOC__ | ||
{{Idiopathic pulmonary fibrosis}} | {{Idiopathic pulmonary fibrosis}} | ||
{{CMG}} | {{CMG}}; {{AE}} {{AEL}} | ||
==Overview== | ==Overview== | ||
[[Lung transplantation]] is essential in treatment of patients with idiopathic pulmonary fibrosis. Pulmonary fibrosis is the most common interstitial lung disease requiring lung transplant and it should be performed early in order to increase the survival rate. | |||
== Indications == | |||
Indications of [[lung transplantation]] include: | |||
* Patients younger than 65 years old | |||
* Patients with low body mass index (<26 kg/m<sup>2</sup>) | |||
==Surgery== | ==Surgery== | ||
=== Lung transplantation === | |||
* [[Lung transplantation]] is essential in treatment of patients with idiopathic pulmonary fibrosis. Pulmonary fibrosis is the most common interstitial lung disease requiring lung transplant and it should be performed early in order to increase the survival rate.<ref name="pmid12928646">{{cite journal| author=Thabut G, Mal H, Castier Y, Groussard O, Brugière O, Marrash-Chahla R et al.| title=Survival benefit of lung transplantation for patients with idiopathic pulmonary fibrosis. | journal=J Thorac Cardiovasc Surg | year= 2003 | volume= 126 | issue= 2 | pages= 469-75 | pmid=12928646 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12928646 }}</ref> | |||
* Time of referral to lung transplantation: <ref name="pmid25085497">{{cite journal| author=Weill D, Benden C, Corris PA, Dark JH, Davis RD, Keshavjee S et al.| title=A consensus document for the selection of lung transplant candidates: 2014--an update from the Pulmonary Transplantation Council of the International Society for Heart and Lung Transplantation. | journal=J Heart Lung Transplant | year= 2015 | volume= 34 | issue= 1 | pages= 1-15 | pmid=25085497 | doi=10.1016/j.healun.2014.06.014 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25085497 }}</ref> | |||
** Confirmed histopathologic or radiographic findings of usual interstitial pneumonitis (UIP) regardless of lung function | |||
** [[Forced vital capacity]] ([[FVC]]) <80% predicted | |||
** [[Diffusion capacity]] of the lung for carbon monoxide ([[DLCO]]) <40% predicted. | |||
** Lung functional limitation (eg, [[dyspnea]]) | |||
* Time of listing:<ref name="pmid250854972">{{cite journal| author=Weill D, Benden C, Corris PA, Dark JH, Davis RD, Keshavjee S et al.| title=A consensus document for the selection of lung transplant candidates: 2014--an update from the Pulmonary Transplantation Council of the International Society for Heart and Lung Transplantation. | journal=J Heart Lung Transplant | year= 2015 | volume= 34 | issue= 1 | pages= 1-15 | pmid=25085497 | doi=10.1016/j.healun.2014.06.014 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25085497 }}</ref> | |||
** Decline in [[FVC]] ≥10% during 6 months of follow-up | |||
** Decline in [[DLCO]] ≥15% during 6 months of follow-up | |||
** Development of [[pulmonary hypertension]] | |||
** [[Hospitalization]] due to acute exacerbation | |||
==References== | ==References== | ||
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[[Category:Pulmonology]] | [[Category:Pulmonology]] | ||
[[Category:Medicine]] | |||
[[Category:Up-To-Date]] | |||
[[Category:Primary Care] |
Latest revision as of 18:43, 9 April 2018
Idiopathic pulmonary fibrosis Microchapters |
Differentiating Idiopathic pulmonary fibrosis from other Diseases |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmed Elsaiey, MBBCH [2]
Overview
Lung transplantation is essential in treatment of patients with idiopathic pulmonary fibrosis. Pulmonary fibrosis is the most common interstitial lung disease requiring lung transplant and it should be performed early in order to increase the survival rate.
Indications
Indications of lung transplantation include:
- Patients younger than 65 years old
- Patients with low body mass index (<26 kg/m2)
Surgery
Lung transplantation
- Lung transplantation is essential in treatment of patients with idiopathic pulmonary fibrosis. Pulmonary fibrosis is the most common interstitial lung disease requiring lung transplant and it should be performed early in order to increase the survival rate.[1]
- Time of referral to lung transplantation: [2]
- Confirmed histopathologic or radiographic findings of usual interstitial pneumonitis (UIP) regardless of lung function
- Forced vital capacity (FVC) <80% predicted
- Diffusion capacity of the lung for carbon monoxide (DLCO) <40% predicted.
- Lung functional limitation (eg, dyspnea)
- Time of listing:[3]
- Decline in FVC ≥10% during 6 months of follow-up
- Decline in DLCO ≥15% during 6 months of follow-up
- Development of pulmonary hypertension
- Hospitalization due to acute exacerbation
References
- ↑ Thabut G, Mal H, Castier Y, Groussard O, Brugière O, Marrash-Chahla R; et al. (2003). "Survival benefit of lung transplantation for patients with idiopathic pulmonary fibrosis". J Thorac Cardiovasc Surg. 126 (2): 469–75. PMID 12928646.
- ↑ Weill D, Benden C, Corris PA, Dark JH, Davis RD, Keshavjee S; et al. (2015). "A consensus document for the selection of lung transplant candidates: 2014--an update from the Pulmonary Transplantation Council of the International Society for Heart and Lung Transplantation". J Heart Lung Transplant. 34 (1): 1–15. doi:10.1016/j.healun.2014.06.014. PMID 25085497.
- ↑ Weill D, Benden C, Corris PA, Dark JH, Davis RD, Keshavjee S; et al. (2015). "A consensus document for the selection of lung transplant candidates: 2014--an update from the Pulmonary Transplantation Council of the International Society for Heart and Lung Transplantation". J Heart Lung Transplant. 34 (1): 1–15. doi:10.1016/j.healun.2014.06.014. PMID 25085497.
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