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==Overview==
==[[Mixed connective tissue disease overview|Overview]]==
'''Mixed connective tissue disease''' ('''MCTD''') or ''Sharp's syndrome'' is a human [[autoimmune disease]] in which the [[immune system]] attacks the body. MCTD combines features of [[polymyositis]], [[systemic lupus erythematosus]], and [[systemic scleroderma]] and is thus considered an [[overlap syndrome]]. MCTD commonly causes [[arthritis|joint pain/swelling]], [[Raynaud phenomenon]], [[myositis|muscle inflammation]], and [[sclerodactyly|scarring of the skin of the hand]]. It does not typically cause [[kidney]] disease or [[seizure]]s. Distinguishing laboratory characteristics are a positive, speckled [[anti-nuclear antibody]] and an [[anti-U1-RNP antibody]].<ref>Venables PJ. ''Mixed connective tissue disease.'' Lupus. 2006;15(3):132-7. PMID 1663436</ref> 


== References ==
==[[Mixed connective tissue disease historical perspective|Historical Perspective]]==
<references />


==[[Mixed connective tissue disease classification scheme|Classification]]==


==[[Mixed connective tissue disease pathophysiology|Pathophysiology]]==


[[Category:Diseases involving the fasciae]]
==[[Mixed connective tissue disease causes|Causes]]==
 
==[[Differentiating Mixed connective tissue disease from other diseases|Differentiating Any Disease from other Diseases]]==
 
==[[Mixed connective tissue disease epidemiology and demographics|Epidemiology and Demographics]]==
 
==[[Mixed connective tissue disease risk factors|Risk Factors]]==
 
==[[Mixed connective tissue disease screening|Screening]]==
 
==[[Mixed connective tissue disease natural history, complications and prognosis|Natural History, Complications and Prognosis]]==
 
==Diagnosis==
[[Mixed connective tissue disease history and symptoms|History and Symptoms]] | [[Mixed connective tissue disease physical examination|Physical Examination]] | [[Mixed connective tissue disease laboratory tests|Laboratory Findings]] | [[Mixed connective tissue disease electrocardiogram|Electrocardiogram]] | [[Mixed connective tissue disease chest x ray|Chest X Ray]] | [[Mixed connective tissue disease CT|CT]] | [[Mixed connective tissue disease MRI|MRI]] | [[Mixed connective tissue disease ultrasound or echocardiography|ultrasound or echocardiography]] | [[Mixed connective tissue disease other imaging findings|Other Imaging Findings]] | [[Mixed connective tissue disease other diagnostic studies|Other Diagnostic Studies]]
 
==Treatment==
[[Mixed connective tissue disease medical therapy|Medical Therapy]] | [[Mixed connective tissue disease surgery|Surgery]] | [[Mixed connective tissue disease primary prevention|Primary Prevention]] | [[Mixed connective tissue disease secondary prevention|Secondary Prevention]] | [[Mixed connective tissue disease Future or Investigational Therapies|Future or Investigational Therapies]]
 
==Case Studies==
[[Type page name here case study one|Case #1]]
 
 
[[Category:Medicine]]
[[Category:Up-To-Date]]
[[Category:Rheumatology]]
[[Category:Rheumatology]]
[[fr:Syndrome de Sharp]]
[[nl:Mixed connective tissue disease]]
[[ja:混合性結合組織病]]
[[sv:Mixed Connective Tissue Disease]]


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Latest revision as of 15:36, 8 May 2018

Mixed connective tissue disease Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Mixed connective tissue disease from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Study of Choice

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

X Ray

CT

MRI

Echocardiography or Ultrasound

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Mixed connective tissue disease On the Web

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X-rays
Echo & Ultrasound
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MRI

Ongoing Trials at Clinical Trials.gov

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on Mixed connective tissue disease

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Blogs onMixed connective tissue disease

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Risk calculators and risk factors for Mixed connective tissue disease

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Shaghayegh Habibi, M.D.[2]

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Any Disease from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms | Physical Examination | Laboratory Findings | Electrocardiogram | Chest X Ray | CT | MRI | ultrasound or echocardiography | Other Imaging Findings | Other Diagnostic Studies

Treatment

Medical Therapy | Surgery | Primary Prevention | Secondary Prevention | Future or Investigational Therapies

Case Studies

Case #1

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