Lead poisoning laboratory findings: Difference between revisions
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Created page with "__NOTOC__ {{Lead poisoning}} {{CMG}}; {{AE}} ==Overview== An elevated/reduced concentration of serum/blood/urinary/CSF/other [lab test] is diagnostic of [disease name]. OR..." |
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{{Lead poisoning}} | {{Lead poisoning}} | ||
{{CMG}}; {{AE}} | {{CMG}}; {{AE}}{{AKS}} | ||
==Overview== | ==Overview== | ||
Elevated venous blood lead levels and basophilic stippling of red blood cells on peripheral smear are the the most important and diagnostic laboratory findings in [[lead poisoning]]. | |||
==Laboratory Findings== | ==Laboratory Findings== | ||
*Laboratory findings consistent with the diagnosis of [[lead poisoning]] include: | |||
**Basophilic stippling of red blood cells <ref name="pmid28620106">{{cite journal| author=Chan NCN, Chan KP| title=Coarse basophilic stippling in lead poisoning. | journal=Blood | year= 2017 | volume= 129 | issue= 24 | pages= 3270 | pmid=28620106 | doi=10.1182/blood-2017-03-773499 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=28620106 }} </ref> | |||
**[[Iron deficiency anemia]] (microcytosis and hypochromia) <ref name="pmid27172444">{{cite journal| author=Hoffmanová I, Kačírková P, Kučerová I, Ševčík R, Sánchez D| title=[Lead poisoning. A surprising cause of constipation, abdominal pain and anemia]. | journal=Vnitr Lek | year= 2016 | volume= 62 | issue= 2 | pages= 157-63 | pmid=27172444 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27172444 }} </ref> | |||
**Elevated venous blood lead levels | |||
**K-fluorescent X-ray metering can measure bone-lead. | |||
Shown below is an image depicting basophilic stippling in a blood smear of a patient with lead poisoning.<br> | |||
[[File:Lead poisoning - blood film.jpg|Basophilic stippling in a blood smear of a patient with lead poisoning]] | |||
==References== | ==References== | ||
Latest revision as of 15:47, 15 August 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aksiniya Stevasarova, M.D.
Overview
Elevated venous blood lead levels and basophilic stippling of red blood cells on peripheral smear are the the most important and diagnostic laboratory findings in lead poisoning.
Laboratory Findings
- Laboratory findings consistent with the diagnosis of lead poisoning include:
- Basophilic stippling of red blood cells [1]
- Iron deficiency anemia (microcytosis and hypochromia) [2]
- Elevated venous blood lead levels
- K-fluorescent X-ray metering can measure bone-lead.
Shown below is an image depicting basophilic stippling in a blood smear of a patient with lead poisoning.
References
- ↑ Chan NCN, Chan KP (2017). "Coarse basophilic stippling in lead poisoning". Blood. 129 (24): 3270. doi:10.1182/blood-2017-03-773499. PMID 28620106.
- ↑ Hoffmanová I, Kačírková P, Kučerová I, Ševčík R, Sánchez D (2016). "[Lead poisoning. A surprising cause of constipation, abdominal pain and anemia]". Vnitr Lek. 62 (2): 157–63. PMID 27172444.