Paroxysmal nocturnal hemoglobinuria surgery: Difference between revisions

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Latest revision as of 01:23, 22 August 2018

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmed Elsaiey, MBBCH [2]

Surgical intervention is not recommended for the management of paroxysmal nocturnal hemoglobinuria.

Surgical intervention is not recommended for the management of paroxysmal nocturnal hemoglobinuria.

@@ Line 1: / Line 1: @@
 __NOTOC__
 {{Paroxysmal nocturnal hemoglobinuria}}
-{{CMG}}; {{AE}}
+{{CMG}}; {{AE}} {{AEL}}
 ==Overview==
+Surgical intervention is not recommended for the management of paroxysmal nocturnal hemoglobinuria.
 ==Surgery==
+Surgical intervention is not recommended for the management of paroxysmal nocturnal hemoglobinuria.
-=== Hematopoietic cell transplantation ===
-* Hematopoietic stem cell transplantation is an important curative therapy for paroxysmal nocturnal hemoglobinuria.
-* Stem cell transplantation is usually reserved for the severely affected patients and is indicated for the following type of patients:<ref name="pmid28013015">{{cite journal| author=DeZern AE, Zahurak M, Symons H, Cooke K, Jones RJ, Brodsky RA| title=Alternative Donor Transplantation with High-Dose Post-Transplantation Cyclophosphamide for Refractory Severe Aplastic Anemia. | journal=Biol Blood Marrow Transplant | year= 2017 | volume= 23 | issue= 3 | pages= 498-504 | pmid=28013015 | doi=10.1016/j.bbmt.2016.12.628 | pmc=5373094 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=28013015  }}</ref>
-** Patients with severe aplastic anemia who are HLA matched donor.
-** Patients with myelodysplastic syndromes
-** Patients who are unresponsive to the anti complement therapy (eculizumab)
-* Outcomes of the transplantation therapy:
-**
 ==References==