Myasthenia gravis CT: Difference between revisions
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==Overview== | ==Overview== | ||
Findings on CT scan suggestive of MG are mostly thymic masses such as thymic hyperplasia and thymoma. | |||
==CT== | ==CT== | ||
CT scan may be helpful in the diagnosis of myasthenia gravis. Findings on CT scan suggestive of MG are mostly thymic masses. So many studies suggested a relationship between myasthenia gravis and thymus. This disease mostly occurs in patients with thymic hyperplasia and thymoma and the removal of thymus can reduce the clinical symptom of the patients. Based on this fact, detection of these thymic masses is very important in management of myasthenia gravis.<ref name="pmid7423369">{{cite journal |vauthors=Wechsler AS, Olanow CW |title=Myasthenia gravis |journal=Surg. Clin. North Am. |volume=60 |issue=4 |pages=931–45 |date=August 1980 |pmid=7423369 |doi= |url=}}</ref><ref name="pmid89275">{{cite journal |vauthors=Elias SB, Appel SH |title=Current concepts of pathogenesis and treatment of myasthenia gravis |journal=Med. Clin. North Am. |volume=63 |issue=4 |pages=745–57 |date=July 1979 |pmid=89275 |doi= |url=}}</ref><ref name="pmid7457692">{{cite journal |vauthors=Mintz S, Petersen SR, MacFarland D, Petajan J, Richards RC |title=The current role of thymectomy for myasthenia gravis |journal=Am. J. Surg. |volume=140 |issue=6 |pages=734–7 |date=December 1980 |pmid=7457692 |doi= |url=}}</ref><ref name="pmid4421048">{{cite journal |vauthors=Cohn HE, Solit RW, Schatz NJ, Schlezinger N |title=Surgical treatment in myasthenia gravis. A 27 year experience |journal=J. Thorac. Cardiovasc. Surg. |volume=68 |issue=6 |pages=876–85 |date=December 1974 |pmid=4421048 |doi= |url=}}</ref><ref name="pmid647191">{{cite journal |vauthors=Fraser K, Simpson JA, Crawford J |title=The place of surgery in the treatment of myasthenia gravis |journal=Br J Surg |volume=65 |issue=5 |pages=301–4 |date=May 1978 |pmid=647191 |doi= |url=}}</ref> CT scan is very sensitive in identifying mediastinal masses but it’s not specific and it cannot differentiate thymomas from nonthymomatous masses.<ref name="pmid6600322">{{cite journal |vauthors=Brown LR, Muhm JR, Sheedy PF, Unni KK, Bernatz PE, Hermann RC |title=The value of computed tomography in myasthenia gravis |journal=AJR Am J Roentgenol |volume=140 |issue=1 |pages=31–5 |date=January 1983 |pmid=6600322 |doi=10.2214/ajr.140.1.31 |url=}}</ref> | * CT scan may be helpful in the diagnosis of myasthenia gravis. | ||
* Findings on CT scan suggestive of MG are mostly thymic masses. | |||
* So many studies suggested a relationship between myasthenia gravis and thymus. This disease mostly occurs in patients with thymic hyperplasia and thymoma and the removal of thymus can reduce the clinical symptom of the patients. | |||
* Based on this fact, detection of these thymic masses is very important in management of myasthenia gravis.<ref name="pmid7423369">{{cite journal |vauthors=Wechsler AS, Olanow CW |title=Myasthenia gravis |journal=Surg. Clin. North Am. |volume=60 |issue=4 |pages=931–45 |date=August 1980 |pmid=7423369 |doi= |url=}}</ref><ref name="pmid89275">{{cite journal |vauthors=Elias SB, Appel SH |title=Current concepts of pathogenesis and treatment of myasthenia gravis |journal=Med. Clin. North Am. |volume=63 |issue=4 |pages=745–57 |date=July 1979 |pmid=89275 |doi= |url=}}</ref><ref name="pmid7457692">{{cite journal |vauthors=Mintz S, Petersen SR, MacFarland D, Petajan J, Richards RC |title=The current role of thymectomy for myasthenia gravis |journal=Am. J. Surg. |volume=140 |issue=6 |pages=734–7 |date=December 1980 |pmid=7457692 |doi= |url=}}</ref><ref name="pmid4421048">{{cite journal |vauthors=Cohn HE, Solit RW, Schatz NJ, Schlezinger N |title=Surgical treatment in myasthenia gravis. A 27 year experience |journal=J. Thorac. Cardiovasc. Surg. |volume=68 |issue=6 |pages=876–85 |date=December 1974 |pmid=4421048 |doi= |url=}}</ref><ref name="pmid647191">{{cite journal |vauthors=Fraser K, Simpson JA, Crawford J |title=The place of surgery in the treatment of myasthenia gravis |journal=Br J Surg |volume=65 |issue=5 |pages=301–4 |date=May 1978 |pmid=647191 |doi= |url=}}</ref> | |||
* CT scan is very sensitive in identifying mediastinal masses but it’s not specific and it cannot differentiate thymomas from nonthymomatous masses.<ref name="pmid6600322">{{cite journal |vauthors=Brown LR, Muhm JR, Sheedy PF, Unni KK, Bernatz PE, Hermann RC |title=The value of computed tomography in myasthenia gravis |journal=AJR Am J Roentgenol |volume=140 |issue=1 |pages=31–5 |date=January 1983 |pmid=6600322 |doi=10.2214/ajr.140.1.31 |url=}}</ref> | |||
==References== | ==References== | ||
Latest revision as of 18:11, 28 November 2018
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Overview
Findings on CT scan suggestive of MG are mostly thymic masses such as thymic hyperplasia and thymoma.
CT
- CT scan may be helpful in the diagnosis of myasthenia gravis.
- Findings on CT scan suggestive of MG are mostly thymic masses.
- So many studies suggested a relationship between myasthenia gravis and thymus. This disease mostly occurs in patients with thymic hyperplasia and thymoma and the removal of thymus can reduce the clinical symptom of the patients.
- Based on this fact, detection of these thymic masses is very important in management of myasthenia gravis.[1][2][3][4][5]
- CT scan is very sensitive in identifying mediastinal masses but it’s not specific and it cannot differentiate thymomas from nonthymomatous masses.[6]
References
- ↑ Wechsler AS, Olanow CW (August 1980). "Myasthenia gravis". Surg. Clin. North Am. 60 (4): 931–45. PMID 7423369.
- ↑ Elias SB, Appel SH (July 1979). "Current concepts of pathogenesis and treatment of myasthenia gravis". Med. Clin. North Am. 63 (4): 745–57. PMID 89275.
- ↑ Mintz S, Petersen SR, MacFarland D, Petajan J, Richards RC (December 1980). "The current role of thymectomy for myasthenia gravis". Am. J. Surg. 140 (6): 734–7. PMID 7457692.
- ↑ Cohn HE, Solit RW, Schatz NJ, Schlezinger N (December 1974). "Surgical treatment in myasthenia gravis. A 27 year experience". J. Thorac. Cardiovasc. Surg. 68 (6): 876–85. PMID 4421048.
- ↑ Fraser K, Simpson JA, Crawford J (May 1978). "The place of surgery in the treatment of myasthenia gravis". Br J Surg. 65 (5): 301–4. PMID 647191.
- ↑ Brown LR, Muhm JR, Sheedy PF, Unni KK, Bernatz PE, Hermann RC (January 1983). "The value of computed tomography in myasthenia gravis". AJR Am J Roentgenol. 140 (1): 31–5. doi:10.2214/ajr.140.1.31. PMID 6600322.