Sideroblastic anemia surgery: Difference between revisions
Jump to navigation
Jump to search
No edit summary |
Shyam Patel (talk | contribs) No edit summary |
||
| (5 intermediate revisions by 3 users not shown) | |||
| Line 1: | Line 1: | ||
__NOTOC__ | __NOTOC__ | ||
{{Sideroblastic anemia}} | {{Sideroblastic anemia}} | ||
{{CMG}} | {{CMG}} {{AE}} {{N.F}} | ||
==Overview== | ==Overview== | ||
In severe cases, | In severe cases, [[bone marrow]] transplant is the only option with limited information about the success rate. | ||
==Surgery== | |||
* [[Hematopoietic stem cell transplantation|Bone marrow transplantation]] | |||
* [[Liver transplantation]] | |||
== Indications == | |||
* Surgery is not the first-line treatment option for patients with sideroblastic anemia.<ref name="pmid27026139">{{cite journal |vauthors=Rouault TA |title=Mitochondrial iron overload: causes and consequences |journal=Curr. Opin. Genet. Dev. |volume=38 |issue= |pages=31–37 |date=June 2016 |pmid=27026139 |pmc=5035716 |doi=10.1016/j.gde.2016.02.004 |url=}}</ref> | |||
* The [[Indications and usage|indications]] for surgery are: | |||
** Young patients with congenital sideroblastic anemia, not responsive to [[pyridoxine]] | |||
** [[Blood transfusion|Transfusion]] dependent patients | |||
** [[Liver cirrhosis]] | |||
** [[Iron overload disorder|Iron overload]] refractory to [[iron]] chelation therapy | |||
** [[Iron overload disorder|Iron overload]] refractory to [[phlebotomy]] | |||
== Contraindications == | |||
* Patients with organ damage from secondary hemochromatosis | |||
* Poor surgical candidacy | |||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
| Line 10: | Line 29: | ||
{{WS}} | {{WS}} | ||
[[Category:Hematology]] | [[Category:Hematology]] | ||
Latest revision as of 20:03, 19 December 2018
|
Sideroblastic anemia Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Sideroblastic anemia surgery On the Web |
|
American Roentgen Ray Society Images of Sideroblastic anemia surgery |
|
Risk calculators and risk factors for Sideroblastic anemia surgery |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Nazia Fuad M.D.
Overview
In severe cases, bone marrow transplant is the only option with limited information about the success rate.
Surgery
Indications
- Surgery is not the first-line treatment option for patients with sideroblastic anemia.[1]
- The indications for surgery are:
- Young patients with congenital sideroblastic anemia, not responsive to pyridoxine
- Transfusion dependent patients
- Liver cirrhosis
- Iron overload refractory to iron chelation therapy
- Iron overload refractory to phlebotomy
Contraindications
- Patients with organ damage from secondary hemochromatosis
- Poor surgical candidacy
References
- ↑ Rouault TA (June 2016). "Mitochondrial iron overload: causes and consequences". Curr. Opin. Genet. Dev. 38: 31–37. doi:10.1016/j.gde.2016.02.004. PMC 5035716. PMID 27026139.