Disseminated intravascular coagulation Prevention: Difference between revisions
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==Prevention== | ==Prevention== | ||
There are no established measures for the prevention of [[DIC]]. The threshold of initiation of prevention therapy for [[bleeding]] in [[DIC]] is a [[platelet count]] of ≥10,000/microL. Some studies suggest a [[platelet count]] of 20,000/microL without [[bleeding]].<ref name="pmid26676927">{{cite journal |vauthors=Squizzato A, Hunt BJ, Kinasewitz GT, Wada H, Ten Cate H, Thachil J, Levi M, Vicente V, D'Angelo A, Di Nisio M |title=Supportive management strategies for disseminated intravascular coagulation. An international consensus |journal=Thromb. Haemost. |volume=115 |issue=5 |pages=896–904 |date=May 2016 |pmid=26676927 |doi=10.1160/TH15-09-0740 |url=}}</ref> There is little evidence to support preventive measures for [[thrombosis]] in [[DIC]]. | There are no established measures for the prevention of [[DIC]]. The threshold of initiation of prevention therapy for [[bleeding]] in [[DIC]] is a [[platelet count]] of ≥10,000/microL. Some studies suggest a [[platelet count]] of 20,000/microL without [[bleeding]].<ref name="pmid26676927">{{cite journal |vauthors=Squizzato A, Hunt BJ, Kinasewitz GT, Wada H, Ten Cate H, Thachil J, Levi M, Vicente V, D'Angelo A, Di Nisio M |title=Supportive management strategies for disseminated intravascular coagulation. An international consensus |journal=Thromb. Haemost. |volume=115 |issue=5 |pages=896–904 |date=May 2016 |pmid=26676927 |doi=10.1160/TH15-09-0740 |url=}}</ref> There is little evidence to support preventive measures for [[thrombosis]] in [[DIC]]. Some experts maintain a fibrinogen level above 100 mg/dl in order to prevent complications of DIC. This can be achieved via transfusion of cryoprecipitate. | ||
==References== | ==References== | ||
Latest revision as of 03:16, 24 December 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Omer Kamal, M.D.[2]
Overview
There are no established measures for the prevention of DIC. The threshold of initiation of prevention therapy for bleeding in DIC is a platelet count of ≥10,000/microL. Some studies suggest a platelet count of 20,000/microL without bleeding. There is little evidence to support preventive measures for thrombosis in DIC.
Prevention
There are no established measures for the prevention of DIC. The threshold of initiation of prevention therapy for bleeding in DIC is a platelet count of ≥10,000/microL. Some studies suggest a platelet count of 20,000/microL without bleeding.[1] There is little evidence to support preventive measures for thrombosis in DIC. Some experts maintain a fibrinogen level above 100 mg/dl in order to prevent complications of DIC. This can be achieved via transfusion of cryoprecipitate.
References
- ↑ Squizzato A, Hunt BJ, Kinasewitz GT, Wada H, Ten Cate H, Thachil J, Levi M, Vicente V, D'Angelo A, Di Nisio M (May 2016). "Supportive management strategies for disseminated intravascular coagulation. An international consensus". Thromb. Haemost. 115 (5): 896–904. doi:10.1160/TH15-09-0740. PMID 26676927.