Sarcomatoid carcinoma of the lung causes: Difference between revisions

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__NOTOC__
__NOTOC__
{{Sarcomatoid carcinoma of the lung causes}}
{{Sarcomatoid carcinoma of the lung}}
 
{{CMG}}; {{AE}} {{Trusha}}


{{CMG}}; {{AE}}
==Overview==
==Overview==
There are no direct causes of sarcomatoid carcinoma of the lung. However, there are a few risk factors that can lead to genetic mutation and cause sarcomatoid carcinoma of the lung.
The direct cause of sarcomatoid carcinoma of the lung is [[DNA mutations]] that often result in either activation of [[Proto-oncogene|proto-oncogenes]] (e.g. [[KRAS|K-RAS]]) or the inactivation of [[Tumor suppressor gene|tumor suppressor genes]] (e.g. [[TP53]]) or both. The risk of these genetic mutations may be increased following exposure to environmental components.


==Causes==
==Causes==
===Life-threatening Causes===
*The direct cause of lung cancers is DNA mutations that often result in either activation of proto-oncogenes (e.g. [[KRAS|K-RAS]]) or the inactivation of [[Tumor suppressor gene|tumor suppressor genes]] (e.g. [[TP53]]) or both.<ref name="pmid23122493">{{cite journal |vauthors=Karachaliou N, Mayo C, Costa C, Magrí I, Gimenez-Capitan A, Molina-Vila MA, Rosell R |title=KRAS mutations in lung cancer |journal=Clin Lung Cancer |volume=14 |issue=3 |pages=205–14 |year=2013 |pmid=23122493 |doi=10.1016/j.cllc.2012.09.007 |url=}}</ref>
*There are no direct causes of sarcomatoid carcinoma of the lung. However, there are a few risk factors that can lead to genetic mutation and cause sarcomatoid carcinoma of the lung.
*The risk of these genetic [[Mutation|mutations]] may be increased following exposure to environmental components, which are regarded as risk factors that predispose to the development of [[lung cancer]].
 
===Common Causes===
Common causes of [disease name] may include:
*[Cause1]
*[Cause2]
*[Cause3]
 
 
OR
 
 
*[Disease name] is caused by an infection with [pathogen name].
*[Pathogen name] is caused by [pathogen name].
 
===Less Common Causes===
Less common causes of [disease name] include:
*[Cause1]
*[Cause2]
*[Cause3]
 
===Genetic Causes===
*[Disease name] is caused by a mutation in the [gene name] gene.
 
===Causes by Organ System===
 
{|style="width:80%; height:100px" border="1"
|style="height:100px"; style="width:25%" border="1" bgcolor="LightSteelBlue" |'''Cardiovascular'''
|style="height:100px"; style="width:75%" border="1" bgcolor="Beige" | No underlying causes
|-
|bgcolor="LightSteelBlue"| '''Chemical/Poisoning'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Dental'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Dermatologic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Drug Side Effect'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Ear Nose Throat'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Endocrine'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Environmental'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Gastroenterologic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Genetic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Hematologic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Iatrogenic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Infectious Disease'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Musculoskeletal/Orthopedic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Neurologic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Nutritional/Metabolic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Obstetric/Gynecologic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Oncologic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Ophthalmologic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Overdose/Toxicity'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Psychiatric'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Pulmonary'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Renal/Electrolyte'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Rheumatology/Immunology/Allergy'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Sexual'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Trauma'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Urologic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Miscellaneous'''
|bgcolor="Beige"| No underlying causes
|-
|}


 
*To view a comprehensive list of risk factors that increase the risk of lung cancer, click [[Lung cancer risk factors|'''here''']].
===Causes in Alphabetical Order===
List the causes of the disease in alphabetical order:
<div style="-moz-column-count:3; column-count:3;">
* Cause 1
* Cause 2
* Cause 3
* Cause 4
* Cause 5
* Cause 6
* Cause 7
* Cause 8
* Cause 9
* Cause 10
</div>


==References==
==References==
{{Reflist|2}}
{{reflist|2}}


{{WH}}
{{WH}}
{{WS}}
{{WS}}
[[Category: (name of the system)]]
{{Tumors}}
 
[[Category:Disease]]
[[Category:Types of cancer]]
[[Category:Pulmonology]]
[[Category:Lung cancer]]
[[Category:Oncology]]
[[Category:Medicine]]
[[Category:Surgery]]

Latest revision as of 20:01, 3 January 2019

Sarcomatoid Carcinoma of the Lung Microchapters

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Overview

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Causes

Differentiating Sarcomatoid Carcinoma of the Lung from other Diseases

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Risk calculators and risk factors for Sarcomatoid carcinoma of the lung causes

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Trusha Tank, M.D.[2]

Overview

The direct cause of sarcomatoid carcinoma of the lung is DNA mutations that often result in either activation of proto-oncogenes (e.g. K-RAS) or the inactivation of tumor suppressor genes (e.g. TP53) or both. The risk of these genetic mutations may be increased following exposure to environmental components.

Causes

  • The direct cause of lung cancers is DNA mutations that often result in either activation of proto-oncogenes (e.g. K-RAS) or the inactivation of tumor suppressor genes (e.g. TP53) or both.[1]
  • The risk of these genetic mutations may be increased following exposure to environmental components, which are regarded as risk factors that predispose to the development of lung cancer.
  • To view a comprehensive list of risk factors that increase the risk of lung cancer, click here.

References

  1. ↑ Karachaliou N, Mayo C, Costa C, Magrí I, Gimenez-Capitan A, Molina-Vila MA, Rosell R (2013). "KRAS mutations in lung cancer". Clin Lung Cancer. 14 (3): 205–14. doi:10.1016/j.cllc.2012.09.007. PMID 23122493.

Template:WH Template:WS Template:Tumors

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