Blue rubber bleb nevus syndrome history and symptoms: Difference between revisions
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__NOTOC__ | __NOTOC__ | ||
{{Blue rubber bleb nevus syndrome}} | |||
{{CMG}} ; {{AE}} {{VKG}} | |||
== Overview == | == Overview == | ||
The majority of patients with [[blue rubber bleb nevus syndrome]] present with symptoms typically at birth like [[blisters]] on the skin, bleeding and [[anemia]]. | The majority of patients with [[blue rubber bleb nevus syndrome]] present with symptoms typically at birth like [[blisters]] on the skin, bleeding and [[anemia]]. | ||
== History and Symptoms == | == History and Symptoms == | ||
* Symptoms of [[blue rubber bleb nevus syndrome]] include [[blisters]] on the skin, bleeding and [[anemia]] | * Symptoms of [[blue rubber bleb nevus syndrome]] include [[blisters]] on the skin, bleeding and [[anemia]]. | ||
=== Common Symptoms === | === Common Symptoms === | ||
Common symptoms of [[blue rubber bleb nevus syndrome]] include: | Common symptoms of [[blue rubber bleb nevus syndrome]] include:<ref name="pmid10881076">{{cite journal |vauthors=Rodrigues D, Bourroul ML, Ferrer AP, Monteiro Neto H, Gonçalves ME, Cardoso SR |title=Blue rubber bleb nevus syndrome |journal=Rev Hosp Clin Fac Med Sao Paulo |volume=55 |issue=1 |pages=29–34 |date=2000 |pmid=10881076 |doi= |url=}}</ref><ref name="pmid15097941">{{cite journal |vauthors=Nahm WK, Moise S, Eichenfield LF, Paller AS, Nathanson L, Malicki DM, Friedlander SF |title=Venous malformations in blue rubber bleb nevus syndrome: variable onset of presentation |journal=J. Am. Acad. Dermatol. |volume=50 |issue=5 Suppl |pages=S101–6 |date=May 2004 |pmid=15097941 |doi=10.1016/S0190 |url=}}</ref><ref name="pmid25493043">{{cite journal |vauthors=Jin XL, Wang ZH, Xiao XB, Huang LS, Zhao XY |title=Blue rubber bleb nevus syndrome: a case report and literature review |journal=World J. Gastroenterol. |volume=20 |issue=45 |pages=17254–9 |date=December 2014 |pmid=25493043 |doi=10.3748/wjg.v20.i45.17254 |url=}}</ref><ref name="pmid27999128">{{cite journal |vauthors=Lybecker MB, Stawowy M, Clausen N |title=Blue rubber bleb naevus syndrome: a rare cause of chronic occult blood loss and iron deficiency anaemia |journal=BMJ Case Rep |volume=2016 |issue= |pages= |date=December 2016 |pmid=27999128 |doi=10.1136/bcr-2016-216963 |url=}}</ref> | ||
* Skin spots which are called [[nevi]] found hundreds in number | * Skin spots which are called [[nevi]] found hundreds in number | ||
* [[Blisters]] on the skin | * [[Blisters]] on the skin | ||
| Line 20: | Line 21: | ||
=== Less Common Symptoms === | === Less Common Symptoms === | ||
Less common symptoms of [[blue rubber bleb nevus syndrome]] include | Less common symptoms of [[blue rubber bleb nevus syndrome]] include:<ref name="pmid108810762">{{cite journal |vauthors=Rodrigues D, Bourroul ML, Ferrer AP, Monteiro Neto H, Gonçalves ME, Cardoso SR |title=Blue rubber bleb nevus syndrome |journal=Rev Hosp Clin Fac Med Sao Paulo |volume=55 |issue=1 |pages=29–34 |date=2000 |pmid=10881076 |doi= |url=}}</ref> | ||
*[[Vascular malformations]] when occur in the joint spaces may result in the following: | |||
** [[Joint pain]] due to damage to the [[cartilage]] | |||
** [[Swelling]] of the involved joints | |||
** Restriction of the joint movement | |||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
Latest revision as of 18:04, 23 January 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Vamsikrishna Gunnam M.B.B.S [2]
Overview
The majority of patients with blue rubber bleb nevus syndrome present with symptoms typically at birth like blisters on the skin, bleeding and anemia.
History and Symptoms
- Symptoms of blue rubber bleb nevus syndrome include blisters on the skin, bleeding and anemia.
Common Symptoms
Common symptoms of blue rubber bleb nevus syndrome include:[1][2][3][4]
- Skin spots which are called nevi found hundreds in number
- Blisters on the skin
- Rubbery feel of nevi due to wrinkled surface
- Severe bleeding from GI tract
- Anemia due to bleeding
- Melena
- Blebs in the eye may cause vision related symptoms
- Blebs in the central nervous system may result in neurological manifestations
Less Common Symptoms
Less common symptoms of blue rubber bleb nevus syndrome include:[5]
- Vascular malformations when occur in the joint spaces may result in the following:
- Joint pain due to damage to the cartilage
- Swelling of the involved joints
- Restriction of the joint movement
References
- ↑ Rodrigues D, Bourroul ML, Ferrer AP, Monteiro Neto H, Gonçalves ME, Cardoso SR (2000). "Blue rubber bleb nevus syndrome". Rev Hosp Clin Fac Med Sao Paulo. 55 (1): 29–34. PMID 10881076.
- ↑ Nahm WK, Moise S, Eichenfield LF, Paller AS, Nathanson L, Malicki DM, Friedlander SF (May 2004). "Venous malformations in blue rubber bleb nevus syndrome: variable onset of presentation". J. Am. Acad. Dermatol. 50 (5 Suppl): S101–6. doi:10.1016/S0190. PMID 15097941.
- ↑ Jin XL, Wang ZH, Xiao XB, Huang LS, Zhao XY (December 2014). "Blue rubber bleb nevus syndrome: a case report and literature review". World J. Gastroenterol. 20 (45): 17254–9. doi:10.3748/wjg.v20.i45.17254. PMID 25493043.
- ↑ Lybecker MB, Stawowy M, Clausen N (December 2016). "Blue rubber bleb naevus syndrome: a rare cause of chronic occult blood loss and iron deficiency anaemia". BMJ Case Rep. 2016. doi:10.1136/bcr-2016-216963. PMID 27999128.
- ↑ Rodrigues D, Bourroul ML, Ferrer AP, Monteiro Neto H, Gonçalves ME, Cardoso SR (2000). "Blue rubber bleb nevus syndrome". Rev Hosp Clin Fac Med Sao Paulo. 55 (1): 29–34. PMID 10881076.