Paget's disease of the breast MRI: Difference between revisions
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{{Paget's disease of the breast}} | {{Paget's disease of the breast}} | ||
{{CMG}} | {{CMG}};{{AE}} {{Preeti}} | ||
==Overview== | ==Overview== | ||
[[MRI]] may be performed to detect the [[breast cancer]] associated with Paget's disease of the breast. In the setting of clinically and [[Mammography|mammographically]] [[occult]] Paget's disease [[MRI]] can be very useful, mainly since [[mammography]] and [[ultrasonography]] have limitations in the evaluation of patients with Paget's disease. [[MRI]] also has a role in the [[preoperative evaluation]] of patients and might be helpful in facilitating [[treatment]] decisions. | |||
==MRI== | |||
*[[MRI]] may be performed to detect the [[breast cancer]] associated with Paget's disease of the breast. | |||
*[[MRI]] is highly sensitive in the detection of clinically occult cancer with no [[Mammogram|mammographic]] and ultrasonographic signs of [[malignancy]]. | |||
*[[MRI]] has a sensitivity of 95% compared to 70% of [[mammography]] in the detection of [[Breast lumps|breast lesions]].<ref name="GaspariRicci2013">{{cite journal|last1=Gaspari|first1=Eleonora|last2=Ricci|first2=Aurora|last3=Liberto|first3=Valeria|last4=Scarano|first4=Angela Lia|last5=Fornari|first5=Maria|last6=Simonetti|first6=Giovanni|title=An Unusual Case of Mammary Paget’s Disease Diagnosed Using Dynamic Contrast-Enhanced MRI|journal=Case Reports in Radiology|volume=2013|year=2013|pages=1–5|issn=2090-6862|doi=10.1155/2013/206235}}</ref> | |||
*[[MRI]] is useful not only to differentiate the normal [[nipple]] from the abnormal one but also to evaluate the extension of the [[tumor]]. | |||
*It may show abnormal [[nipple]] enhancement, thickening of the [[nipple]] [[areola]] complex. | |||
*Even when clinically unsuspected it can show associated enhancment for [[DCIS]] or invasive [[tumor]], or a combination of both. | |||
*[[MRI]] also has a role in the [[preoperative evaluation]] of patients and might be helpful in facilitating [[treatment]] decisions.<ref name="pmid15905723">{{cite journal |vauthors=Frei KA, Bonel HM, Pelte MF, Hylton NM, Kinkel K |title=Paget disease of the breast: findings at magnetic resonance imaging and histopathologic correlation |journal=Invest Radiol |volume=40 |issue=6 |pages=363–7 |date=June 2005 |pmid=15905723 |doi= |url=}}</ref><ref name="pmid17896158">{{cite journal |vauthors=Morrogh M, Morris EA, Liberman L, Borgen PI, King TA |title=The predictive value of ductography and magnetic resonance imaging in the management of nipple discharge |journal=Ann. Surg. Oncol. |volume=14 |issue=12 |pages=3369–77 |date=December 2007 |pmid=17896158 |doi=10.1245/s10434-007-9530-5 |url=}}</ref><ref name="pmid15741305">{{cite journal |vauthors=Amano G, Yajima M, Moroboshi Y, Kuriya Y, Ohuchi N |title=MRI accurately depicts underlying DCIS in a patient with Paget's disease of the breast without palpable mass and mammography findings |journal=Jpn. J. Clin. Oncol. |volume=35 |issue=3 |pages=149–53 |date=March 2005 |pmid=15741305 |doi=10.1093/jjco/hyi044 |url=}}</ref><ref name="pmid15741305">{{cite journal |vauthors=Amano G, Yajima M, Moroboshi Y, Kuriya Y, Ohuchi N, Worathumrong N, Grimes AJ, Smith RJ, Bryant RG, Autrup H, Warwick GP, van Dam-Mieras MC, Slotboom AJ, Pieterson WA, de Haas GH, Daniels LK, Amano G, Yajima M, Moroboshi Y, Kuriya Y, Ohuchi N, Schmoldt A, Benthe HF, Haberland G, Fleet GH, Phaff HJ, McPhie P |title=MRI accurately depicts underlying DCIS in a patient with Paget's disease of the breast without palpable mass and mammography findings |journal=Jpn. J. Clin. Oncol. |volume=35 |issue=3 |pages=149–53 |date=March 2005 |pmid=15741305 |doi=10.1093/jjco/hyi044 |url=}}</ref> | |||
[[File:Paget-disease-of-the-nipple.jpg|250px|thumb|left|MRI showing Paget's disease of the breast [https://radiopaedia.org/cases/paget-disease-of-the-nipple?lang=us source:Case courtesy of Dr Roberto Schubert, Radiopaedia.org, rID: 16098]]] | |||
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==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
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[[Category:Dermatology]] | [[Category:Dermatology]] | ||
[[Category:Breast]] | [[Category:Breast]] | ||
[[Category:Dermatology patient information]] | [[Category:Dermatology patient information]] | ||
[[Category:Oncology patient information]] | [[Category:Oncology patient information]] | ||
[[Category:Patient information]] | [[Category:Patient information]] | ||
[[Category:Mature chapter]] | [[Category:Mature chapter]] | ||
[[Category:Up-To-Date]] | |||
[[Category:Oncology]] | |||
[[Category:Medicine]] | |||
[[Category:Gynecology]] | |||
[[Category:Surgery]] | |||
Latest revision as of 05:44, 26 March 2019
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Paget's disease of the breast Microchapters |
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Differentiating Paget's disease of the breast from other Diseases |
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Diagnosis |
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Treatment |
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Case Studies |
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Paget's disease of the breast MRI On the Web |
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American Roentgen Ray Society Images of Paget's disease of the breast MRI |
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Directions to Hospitals Treating Paget's disease of the breast |
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Risk calculators and risk factors for Paget's disease of the breast MRI |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Preeti Singh, M.B.B.S.[2]
Overview
MRI may be performed to detect the breast cancer associated with Paget's disease of the breast. In the setting of clinically and mammographically occult Paget's disease MRI can be very useful, mainly since mammography and ultrasonography have limitations in the evaluation of patients with Paget's disease. MRI also has a role in the preoperative evaluation of patients and might be helpful in facilitating treatment decisions.
MRI
- MRI may be performed to detect the breast cancer associated with Paget's disease of the breast.
- MRI is highly sensitive in the detection of clinically occult cancer with no mammographic and ultrasonographic signs of malignancy.
- MRI has a sensitivity of 95% compared to 70% of mammography in the detection of breast lesions.[1]
- MRI is useful not only to differentiate the normal nipple from the abnormal one but also to evaluate the extension of the tumor.
- It may show abnormal nipple enhancement, thickening of the nipple areola complex.
- Even when clinically unsuspected it can show associated enhancment for DCIS or invasive tumor, or a combination of both.
- MRI also has a role in the preoperative evaluation of patients and might be helpful in facilitating treatment decisions.[2][3][4][4]
References
- ↑ Gaspari, Eleonora; Ricci, Aurora; Liberto, Valeria; Scarano, Angela Lia; Fornari, Maria; Simonetti, Giovanni (2013). "An Unusual Case of Mammary Paget's Disease Diagnosed Using Dynamic Contrast-Enhanced MRI". Case Reports in Radiology. 2013: 1–5. doi:10.1155/2013/206235. ISSN 2090-6862.
- ↑ Frei KA, Bonel HM, Pelte MF, Hylton NM, Kinkel K (June 2005). "Paget disease of the breast: findings at magnetic resonance imaging and histopathologic correlation". Invest Radiol. 40 (6): 363–7. PMID 15905723.
- ↑ Morrogh M, Morris EA, Liberman L, Borgen PI, King TA (December 2007). "The predictive value of ductography and magnetic resonance imaging in the management of nipple discharge". Ann. Surg. Oncol. 14 (12): 3369–77. doi:10.1245/s10434-007-9530-5. PMID 17896158.
- ↑ 4.0 4.1 Amano G, Yajima M, Moroboshi Y, Kuriya Y, Ohuchi N (March 2005). "MRI accurately depicts underlying DCIS in a patient with Paget's disease of the breast without palpable mass and mammography findings". Jpn. J. Clin. Oncol. 35 (3): 149–53. doi:10.1093/jjco/hyi044. PMID 15741305.