Paget's disease of the breast epidemiology and demographics: Difference between revisions
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__NOTOC__ | __NOTOC__ | ||
{{Paget's disease of the breast}} | {{Paget's disease of the breast}} | ||
{{CMG}} | {{CMG}};{{AE}} {{Preeti}} | ||
==Overview== | ==Overview== | ||
Paget's disease of the breast occurs in 0.5–5% of all breast [[cancer]] cases and is invariably associated with underlying [[Cancer|malignancy]] either overt or occult. [[WHO]] revealed that there are 800,000 up to 1 million new cases of [[breast cancer]] each year. An underlying breast [[carcinoma]] is found in >90% of patients with Paget's disease. The majority of these cases are [[invasive]] [[disease]] although 40 – 45% are associated with [[ductal carcinoma in situ]]. Paget's disease of the breast is more prevalent in postmenopausal women, usually after the sixth decade of life, but it has also been reported in adolescent and elderly patients. [[Females]] are more commonly affected with Paget's disease of the breast than [[males]]. [[Male]] [[breast cancer]] accounts for less than 1% of all [[breast cancer]] and Paget's disease represents 1-3% of all breast malignancies. | |||
==Epidemiology and Demographics== | ==Epidemiology and Demographics== | ||
Paget's disease of the breast occurs in | *Paget's disease of the breast occurs in 0.5–5% of all [[breast cancer]] cases and is invariably associated with underlying [[malignancy]] either overt or occult. | ||
* [[WHO]] revealed that there are 800,000 up to 1 million new cases of [[breast cancer]] each year.<ref name="DelalogeBachelot2016">{{cite journal|last1=Delaloge|first1=Suzette|last2=Bachelot|first2=Thomas|last3=Bidard|first3=François-Clément|last4=Espie|first4=Marc|last5=Brain|first5=Etienne|last6=Bonnefoi|first6=Hervé|last7=Gligorov|first7=Joseph|last8=Dalenc|first8=Florence|last9=Hardy-Bessard|first9=Anne-Claire|last10=Azria|first10=David|last11=Jacquin|first11=Jean-Philippe|last12=Lemonnier|first12=Jérôme|last13=Jacot|first13=William|last14=Goncalves|first14=Anthony|last15=Coutant|first15=Charles|last16=Ganem|first16=Gérard|last17=Petit|first17=Thierry|last18=Penault-Lorca|first18=Frédérique|last19=Debled|first19=Marc|last20=Campone|first20=Mario|last21=Levy|first21=Christelle|last22=Coudert|first22=Bruno|last23=Lortholary|first23=Alain|last24=Venat-Bouvet|first24=Laurence|last25=Grenier|first25=Julien|last26=Bourgeois|first26=Hugues|last27=Asselain|first27=Bernard|last28=Arvis|first28=Johanna|last29=Castro|first29=Martine|last30=Tardivon|first30=Anne|last31=Cox|first31=David G.|last32=Arveux|first32=Patrick|last33=Balleyguier|first33=Corinne|last34=André|first34=Fabrice|last35=Rouzier|first35=Roman|title=Dépistage du cancer du sein : en route vers le futur|journal=Bulletin du Cancer|volume=103|issue=9|year=2016|pages=753–763|issn=00074551|doi=10.1016/j.bulcan.2016.06.005}}</ref> | |||
*An underlying breast carcinoma is found in >90% of patients with Paget's disease. | |||
*The majority of these cases are [[Invasive (medical)|invasive]] [[disease]] although 40 – 45% are associated with [[ductal carcinoma in situ]].<ref name="SubramanianBirch2007">{{cite journal|last1=Subramanian|first1=Ashok|last2=Birch|first2=Hilary|last3=McAvinchey|first3=Rita|last4=Stacey-Clear|first4=Adam|title=Pagets disease of uncertain origin: case report|journal=International Seminars in Surgical Oncology|volume=4|issue=1|year=2007|pages=12|issn=14777800|doi=10.1186/1477-7800-4-12}}</ref> | |||
===Age=== | ===Age=== | ||
* | *Paget's disease of the [[breast]] is more prevalent in [[postmenopausal]] women, usually after the sixth decade of life, but it has also been reported in [[adolescent]] and [[Old age|elderly patients]]. | ||
===Gender=== | ===Gender=== | ||
*Females are more commonly affected with Paget's disease of the breast than males. | *[[Females]] are more commonly affected with Paget's disease of the [[breast]] than [[males]].<ref name="pmid1648987">{{cite journal |vauthors=Dixon AR, Galea MH, Ellis IO, Elston CW, Blamey RW |title=Paget's disease of the nipple |journal=Br J Surg |volume=78 |issue=6 |pages=722–3 |date=June 1991 |pmid=1648987 |doi= |url=}}</ref> | ||
*Male breast cancer represents | *[[Male]] [[breast cancer]] accounts for less than 1% of all breast cancer and Paget's disease represents 1-3% of all [[breast]] malignancies.<ref name="Fouad2011">{{cite journal|last1=Fouad|first1=Dina|title=Paget's disease of the breast in a male with lymphomatoid papulosis: a case report|journal=Journal of Medical Case Reports|volume=5|issue=1|year=2011|pages=43|issn=1752-1947|doi=10.1186/1752-1947-5-43}}</ref> | ||
==References== | ==References== | ||
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[[Category:Breast]] | [[Category:Breast]] | ||
[[Category:Mature chapter]] | [[Category:Mature chapter]] | ||
[[Category:Up-To-Date]] | |||
[[Category:Oncology]] | |||
[[Category:Medicine]] | |||
[[Category:Gynecology]] | |||
[[Category:Surgery]] | |||
Latest revision as of 15:05, 28 March 2019
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Paget's disease of the breast Microchapters |
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Differentiating Paget's disease of the breast from other Diseases |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Preeti Singh, M.B.B.S.[2]
Overview
Paget's disease of the breast occurs in 0.5–5% of all breast cancer cases and is invariably associated with underlying malignancy either overt or occult. WHO revealed that there are 800,000 up to 1 million new cases of breast cancer each year. An underlying breast carcinoma is found in >90% of patients with Paget's disease. The majority of these cases are invasive disease although 40 – 45% are associated with ductal carcinoma in situ. Paget's disease of the breast is more prevalent in postmenopausal women, usually after the sixth decade of life, but it has also been reported in adolescent and elderly patients. Females are more commonly affected with Paget's disease of the breast than males. Male breast cancer accounts for less than 1% of all breast cancer and Paget's disease represents 1-3% of all breast malignancies.
Epidemiology and Demographics
- Paget's disease of the breast occurs in 0.5–5% of all breast cancer cases and is invariably associated with underlying malignancy either overt or occult.
- WHO revealed that there are 800,000 up to 1 million new cases of breast cancer each year.[1]
- An underlying breast carcinoma is found in >90% of patients with Paget's disease.
- The majority of these cases are invasive disease although 40 – 45% are associated with ductal carcinoma in situ.[2]
Age
- Paget's disease of the breast is more prevalent in postmenopausal women, usually after the sixth decade of life, but it has also been reported in adolescent and elderly patients.
Gender
- Females are more commonly affected with Paget's disease of the breast than males.[3]
- Male breast cancer accounts for less than 1% of all breast cancer and Paget's disease represents 1-3% of all breast malignancies.[4]
References
- ↑ Delaloge, Suzette; Bachelot, Thomas; Bidard, François-Clément; Espie, Marc; Brain, Etienne; Bonnefoi, Hervé; Gligorov, Joseph; Dalenc, Florence; Hardy-Bessard, Anne-Claire; Azria, David; Jacquin, Jean-Philippe; Lemonnier, Jérôme; Jacot, William; Goncalves, Anthony; Coutant, Charles; Ganem, Gérard; Petit, Thierry; Penault-Lorca, Frédérique; Debled, Marc; Campone, Mario; Levy, Christelle; Coudert, Bruno; Lortholary, Alain; Venat-Bouvet, Laurence; Grenier, Julien; Bourgeois, Hugues; Asselain, Bernard; Arvis, Johanna; Castro, Martine; Tardivon, Anne; Cox, David G.; Arveux, Patrick; Balleyguier, Corinne; André, Fabrice; Rouzier, Roman (2016). "Dépistage du cancer du sein : en route vers le futur". Bulletin du Cancer. 103 (9): 753–763. doi:10.1016/j.bulcan.2016.06.005. ISSN 0007-4551.
- ↑ Subramanian, Ashok; Birch, Hilary; McAvinchey, Rita; Stacey-Clear, Adam (2007). "Pagets disease of uncertain origin: case report". International Seminars in Surgical Oncology. 4 (1): 12. doi:10.1186/1477-7800-4-12. ISSN 1477-7800.
- ↑ Dixon AR, Galea MH, Ellis IO, Elston CW, Blamey RW (June 1991). "Paget's disease of the nipple". Br J Surg. 78 (6): 722–3. PMID 1648987.
- ↑ Fouad, Dina (2011). "Paget's disease of the breast in a male with lymphomatoid papulosis: a case report". Journal of Medical Case Reports. 5 (1): 43. doi:10.1186/1752-1947-5-43. ISSN 1752-1947.