Hamartoma natural history: Difference between revisions

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{{Hamartoma}}
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==Overview==
==Overview==


If left untreated, hamartomas normally grow slowly and may progress to develop a considerable size, however pulmonary hamartomas have low or no malignant potential. Nevertheless, it is essential to rule out the presence of cancer. Common complications of hamartomas will depend on the location and size. Prognosis is generally regraded as excellent.<ref name="pmid15615988">{{cite journal |vauthors=Marchiori E, Souza AS, Franquet T, Müller NL |title=Diffuse high-attenuation pulmonary abnormalities: a pattern-oriented diagnostic approach on high-resolution CT |journal=AJR Am J Roentgenol |volume=184 |issue=1 |pages=273–82 |year=2005 |pmid=15615988 |doi=10.2214/ajr.184.1.01840273 |url=}}</ref>
If left untreated, [[hamartomas]] normally grow slowly and may progress to develop a considerable size, however [[pulmonary]] [[hamartomas]] have low or no [[malignant]] potential. Nevertheless, it is essential to rule out the presence of [[cancer]]. Common [[complications]] of [[hamartomas]] will depend on the location and size.[[Prognosis]] is generally regarded as excellent.


==Natural History==
==Natural History==


If left untreated, hamartomas normally grow slowly and may progress to develop a considerable size, however pulmonary hamartomas have low or no malignant potential. Nevertheless, it is essential to rule out the presence of cancer.<ref name="pmid15615988">{{cite journal |vauthors=Marchiori E, Souza AS, Franquet T, Müller NL |title=Diffuse high-attenuation pulmonary abnormalities: a pattern-oriented diagnostic approach on high-resolution CT |journal=AJR Am J Roentgenol |volume=184 |issue=1 |pages=273–82 |year=2005 |pmid=15615988 |doi=10.2214/ajr.184.1.01840273 |url=}}</ref>
*If left untreated, [[hamartomas]] normally grow slowly and may progress to develop a considerable size, however [[hamartomas]] no [[malignant]] potential. Nevertheless, it is essential to rule out the presence of [[cancer]].<ref name="pmid15615988">{{cite journal |vauthors=Marchiori E, Souza AS, Franquet T, Müller NL |title=Diffuse high-attenuation pulmonary abnormalities: a pattern-oriented diagnostic approach on high-resolution CT |journal=AJR Am J Roentgenol |volume=184 |issue=1 |pages=273–82 |year=2005 |pmid=15615988 |doi=10.2214/ajr.184.1.01840273 |url=}}</ref>


==Complications==
==Complications==
*Common complications of hamartomas will depend on the location and size of the tumor.<ref name=“wiki"> Hamartomas. Wikipedia https://en.wikipedia.org/wiki/Hamartoma Accessed on December 08, 2015 </ref>
*Common complications of [[hamartomas]] will depend on the location and size of the [[tumor]].<ref name="“wiki&quot;">Hamartomas. Wikipedia https://en.wikipedia.org/wiki/Hamartoma Accessed on December 08, 2015 </ref>
*Large size hamartomas are related with more complications.
*Large [[hamartomas]] are associated with more [[complications]].
*Hamartomas are particularly likely to cause major complications when located in the [[hypothalamus]], [[spleen]], or kidneys.
*[[Hamartomas]] are more likely to cause major [[complications]] when located in the [[hypothalamus]], [[spleen]], or [[kidney]]s.


==Prognosis==
==Prognosis==
*Prognosis is generally regarded as excellent.<ref name="pmid15615988">{{cite journal |vauthors=Marchiori E, Souza AS, Franquet T, Müller NL |title=Diffuse high-attenuation pulmonary abnormalities: a pattern-oriented diagnostic approach on high-resolution CT |journal=AJR Am J Roentgenol |volume=184 |issue=1 |pages=273–82 |year=2005 |pmid=15615988 |doi=10.2214/ajr.184.1.01840273 |url=}}</ref>  
*[[Prognosis]] is generally regarded as excellent because most [[osteochondromas]] cease to grow when skeletal [[Maturity (psychological)|maturity]] is achieved<ref name="pmid15615988">{{cite journal |vauthors=Marchiori E, Souza AS, Franquet T, Müller NL |title=Diffuse high-attenuation pulmonary abnormalities: a pattern-oriented diagnostic approach on high-resolution CT |journal=AJR Am J Roentgenol |volume=184 |issue=1 |pages=273–82 |year=2005 |pmid=15615988 |doi=10.2214/ajr.184.1.01840273 |url=}}</ref>  
*The prognosis varies with the size and location of tumor; small hamartomas have the most favorable prognosis.
*The [[prognosis]] of patients with [[Enchondroma|enchondromatosis]] is difficult to assess.
*The [[prognosis]] also varies with the size and location of [[tumor]], small [[hamartomas]] have the most favorable [[prognosis]].


==References==
==References==
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Latest revision as of 19:35, 5 April 2019

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Maria Fernanda Villarreal, M.D. [2] Vamsikrishna Gunnam M.B.B.S [3]

Overview

If left untreated, hamartomas normally grow slowly and may progress to develop a considerable size, however pulmonary hamartomas have low or no malignant potential. Nevertheless, it is essential to rule out the presence of cancer. Common complications of hamartomas will depend on the location and size.Prognosis is generally regarded as excellent.

Natural History

  • If left untreated, hamartomas normally grow slowly and may progress to develop a considerable size, however hamartomas no malignant potential. Nevertheless, it is essential to rule out the presence of cancer.[1]

Complications

Prognosis

References

  1. 1.0 1.1 Marchiori E, Souza AS, Franquet T, Müller NL (2005). "Diffuse high-attenuation pulmonary abnormalities: a pattern-oriented diagnostic approach on high-resolution CT". AJR Am J Roentgenol. 184 (1): 273–82. doi:10.2214/ajr.184.1.01840273. PMID 15615988.
  2. Hamartomas. Wikipedia https://en.wikipedia.org/wiki/Hamartoma Accessed on December 08, 2015


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