Duchenne muscular dystrophy epidemiology and demographics: Difference between revisions
Jump to navigation
Jump to search
Created page with "__NOTOC__ {{Duchenne muscular dystrophy}} {{CMG}}; {{AE}} {{Fs}} ==Overview== ==Epidemiology and Demographics== ===Incidence=== *The incidence/prevalence of [disease name] i..." |
No edit summary |
||
| (9 intermediate revisions by the same user not shown) | |||
| Line 4: | Line 4: | ||
{{CMG}}; {{AE}} {{Fs}} | {{CMG}}; {{AE}} {{Fs}} | ||
==Overview== | ==Overview== | ||
The incidence of Duchenne [[muscular dystrophy]] is approximately 20 per 100,00 births worldwide. In 2010, the prevalence of Duchenne/ [[Becker's muscular dystrophy|Becker muscular dystrophy]] was estimated to be 1.38 per 10,000 male individuals, ages 5 to 24 years. The [[mortality rate]] of Duchenne [[muscular dystrophy]] is 100%. The [[Symptom|symptoms]] of Duchenne [[muscular dystrophy]] commonly presents in [[children]] younger than 5 years of age. Duchenne [[muscular dystrophy]] usually affects individuals of the Hispanic race. Non-Hispanic white or black individuals are less likely to develop DMD. Since the disease is [[X-linked|X-link recessive]], almost all of the [[patients]] are male but we may have some [[female]] [[Carrier|carriers]] with [[Symptom|symptoms]] as well. | |||
==Epidemiology and Demographics== | ==Epidemiology and Demographics== | ||
===Incidence=== | ===Incidence=== | ||
*The incidence | *The incidence of Duchenne [[muscular dystrophy]] is approximately 20 per 100,00 births worldwide.<ref name="pmid26697447">{{cite journal |vauthors=Stark AE |title=Determinants of the incidence of Duchenne muscular dystrophy |journal=Ann Transl Med |volume=3 |issue=19 |pages=287 |date=November 2015 |pmid=26697447 |pmc=4671860 |doi=10.3978/j.issn.2305-5839.2015.10.45 |url=}}</ref><ref name="RyderLeadley2017">{{cite journal|last1=Ryder|first1=S.|last2=Leadley|first2=R. M.|last3=Armstrong|first3=N.|last4=Westwood|first4=M.|last5=de Kock|first5=S.|last6=Butt|first6=T.|last7=Jain|first7=M.|last8=Kleijnen|first8=J.|title=The burden, epidemiology, costs and treatment for Duchenne muscular dystrophy: an evidence review|journal=Orphanet Journal of Rare Diseases|volume=12|issue=1|year=2017|issn=1750-1172|doi=10.1186/s13023-017-0631-3}}</ref> | ||
===Prevalence=== | ===Prevalence=== | ||
*In 2010, the prevalence of Duchenne/ [[Becker's muscular dystrophy|Becker muscular dystrophy]] was estimated to be 1.38 per 10,000 male individuals, ages 5 to 24 years.<ref name="pmid256871442">{{cite journal |vauthors=Romitti PA, Zhu Y, Puzhankara S, James KA, Nabukera SK, Zamba GK, Ciafaloni E, Cunniff C, Druschel CM, Mathews KD, Matthews DJ, Meaney FJ, Andrews JG, Conway KM, Fox DJ, Street N, Adams MM, Bolen J |title=Prevalence of Duchenne and Becker muscular dystrophies in the United States |journal=Pediatrics |volume=135 |issue=3 |pages=513–21 |date=March 2015 |pmid=25687144 |pmc=4477633 |doi=10.1542/peds.2014-2044 |url=}}</ref> | |||
*In | |||
===Case-fatality rate/Mortality rate=== | ===Case-fatality rate/Mortality rate=== | ||
* | *The [[mortality rate]] of Duchenne [[muscular dystrophy]] is 100%. | ||
===Age=== | ===Age=== | ||
* | *The [[Symptom|symptoms]] of Duchenne [[muscular dystrophy]] commonly presents in [[children]] younger than 5 years of age.<ref name="pmid25687144">{{cite journal |vauthors=Romitti PA, Zhu Y, Puzhankara S, James KA, Nabukera SK, Zamba GK, Ciafaloni E, Cunniff C, Druschel CM, Mathews KD, Matthews DJ, Meaney FJ, Andrews JG, Conway KM, Fox DJ, Street N, Adams MM, Bolen J |title=Prevalence of Duchenne and Becker muscular dystrophies in the United States |journal=Pediatrics |volume=135 |issue=3 |pages=513–21 |date=March 2015 |pmid=25687144 |pmc=4477633 |doi=10.1542/peds.2014-2044 |url=}}</ref> | ||
===Race=== | ===Race=== | ||
* | *Duchenne [[muscular dystrophy]] usually affects individuals of the Hispanic race. Non-Hispanic white or black individuals are less likely to develop DMD. | ||
===Gender=== | ===Gender=== | ||
*[ | *Since the disease is [[X-linked|X-link recessive]], almost all of the [[patients]] are male but we may have some [[female]] [[Carrier|carriers]] with [[Symptom|symptoms]] as well <ref name="Yoshioka2008">{{cite journal|last1=Yoshioka|first1=Mieko|title=Clinically manifesting carriers in Duchenne muscular dystrophy|journal=Clinical Genetics|volume=20|issue=1|year=2008|pages=6–12|issn=00099163|doi=10.1111/j.1399-0004.1981.tb01799.x}}</ref> | ||
=== | |||
=== | |||
==References== | ==References== | ||
Latest revision as of 14:07, 8 May 2019
|
Duchenne muscular dystrophy Microchapters |
|
Differentiating Duchenne muscular dystrophy from other Diseases |
|---|
|
Diagnosis |
|
Treatment |
|
Case Studies |
|
Duchenne muscular dystrophy epidemiology and demographics On the Web |
|
American Roentgen Ray Society Images of Duchenne muscular dystrophy epidemiology and demographics |
|
FDA on Duchenne muscular dystrophy epidemiology and demographics |
|
CDC on Duchenne muscular dystrophy epidemiology and demographics |
|
Duchenne muscular dystrophy epidemiology and demographics in the news |
|
Blogs on Duchenne muscular dystrophy epidemiology and demographics |
|
Risk calculators and risk factors for Duchenne muscular dystrophy epidemiology and demographics |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Fahimeh Shojaei, M.D.
Overview
The incidence of Duchenne muscular dystrophy is approximately 20 per 100,00 births worldwide. In 2010, the prevalence of Duchenne/ Becker muscular dystrophy was estimated to be 1.38 per 10,000 male individuals, ages 5 to 24 years. The mortality rate of Duchenne muscular dystrophy is 100%. The symptoms of Duchenne muscular dystrophy commonly presents in children younger than 5 years of age. Duchenne muscular dystrophy usually affects individuals of the Hispanic race. Non-Hispanic white or black individuals are less likely to develop DMD. Since the disease is X-link recessive, almost all of the patients are male but we may have some female carriers with symptoms as well.
Epidemiology and Demographics
Incidence
- The incidence of Duchenne muscular dystrophy is approximately 20 per 100,00 births worldwide.[1][2]
Prevalence
- In 2010, the prevalence of Duchenne/ Becker muscular dystrophy was estimated to be 1.38 per 10,000 male individuals, ages 5 to 24 years.[3]
Case-fatality rate/Mortality rate
- The mortality rate of Duchenne muscular dystrophy is 100%.
Age
- The symptoms of Duchenne muscular dystrophy commonly presents in children younger than 5 years of age.[4]
Race
- Duchenne muscular dystrophy usually affects individuals of the Hispanic race. Non-Hispanic white or black individuals are less likely to develop DMD.
Gender
- Since the disease is X-link recessive, almost all of the patients are male but we may have some female carriers with symptoms as well [5]
References
- ↑ Stark AE (November 2015). "Determinants of the incidence of Duchenne muscular dystrophy". Ann Transl Med. 3 (19): 287. doi:10.3978/j.issn.2305-5839.2015.10.45. PMC 4671860. PMID 26697447.
- ↑ Ryder, S.; Leadley, R. M.; Armstrong, N.; Westwood, M.; de Kock, S.; Butt, T.; Jain, M.; Kleijnen, J. (2017). "The burden, epidemiology, costs and treatment for Duchenne muscular dystrophy: an evidence review". Orphanet Journal of Rare Diseases. 12 (1). doi:10.1186/s13023-017-0631-3. ISSN 1750-1172.
- ↑ Romitti PA, Zhu Y, Puzhankara S, James KA, Nabukera SK, Zamba GK, Ciafaloni E, Cunniff C, Druschel CM, Mathews KD, Matthews DJ, Meaney FJ, Andrews JG, Conway KM, Fox DJ, Street N, Adams MM, Bolen J (March 2015). "Prevalence of Duchenne and Becker muscular dystrophies in the United States". Pediatrics. 135 (3): 513–21. doi:10.1542/peds.2014-2044. PMC 4477633. PMID 25687144.
- ↑ Romitti PA, Zhu Y, Puzhankara S, James KA, Nabukera SK, Zamba GK, Ciafaloni E, Cunniff C, Druschel CM, Mathews KD, Matthews DJ, Meaney FJ, Andrews JG, Conway KM, Fox DJ, Street N, Adams MM, Bolen J (March 2015). "Prevalence of Duchenne and Becker muscular dystrophies in the United States". Pediatrics. 135 (3): 513–21. doi:10.1542/peds.2014-2044. PMC 4477633. PMID 25687144.
- ↑ Yoshioka, Mieko (2008). "Clinically manifesting carriers in Duchenne muscular dystrophy". Clinical Genetics. 20 (1): 6–12. doi:10.1111/j.1399-0004.1981.tb01799.x. ISSN 0009-9163.