Testicular cancer classification: Difference between revisions
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! style="background:#4479BA; color: #FFFFFF;" align="center" + |Tumors containing both germ cell and sex-cord stromal elements | ! style="background:#4479BA; color: #FFFFFF;" align="center" + |Tumors containing both germ cell and sex-cord stromal elements | ||
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|'''Germ cell tumors derived from germ cell neoplasia in situ:''' | |'''[[Germ cell tumors]] derived from [[Germ cell neoplasm|germ cell neoplasia]] [[in situ]]:''' | ||
* Non-invasive germ cell neoplasia | * Non-invasive [[germ cell]] [[neoplasia]] | ||
**Germ cell neoplasia in situ | **[[Germ cell]] [[neoplasia]] [[in situ]] | ||
**Specific forms of intratubular germ cell tumor neoplasia | **Specific forms of intratubular [[germ cell]] tumor [[neoplasia]] | ||
* Tumors of a single histological type (pure forms) | * [[Tumor|Tumors]] of a single [[histological]] type (pure forms) | ||
**[[Seminoma]] | **[[Seminoma]] | ||
**[[Seminoma with syncytiotrophoblast cells]] | **[[Seminoma|Seminoma with syncytiotrophoblast cells]] | ||
** | **Non-seminomatous [[germ cell]] [[tumors]] | ||
**[[Embryonal carcinoma]] | **[[Embryonal carcinoma]] | ||
** | **[[Yolk sac tumor]], postpubertal-type | ||
**Trophoblastic tumors | **[[Trophoblastic|Trophoblastic tumors]] | ||
***Choriocarcinoma | ***[[Choriocarcinoma]] | ||
***Non-choriocarcinomatous trophoblastic tumors | ***Non-choriocarcinomatous [[Trophoblastic|trophoblastic tumors]] | ||
***Placental site trophoblastic tumor | ***[[Placental]] site [[trophoblastic]] [[tumor]] | ||
***Epitheliol trophoblastic tumor | ***Epitheliol [[Trophoblastic|trophoblastic tumor]] | ||
***Cystic trophoblastic tumor | ***[[Cystic]] [[trophoblastic]] tumor | ||
**Teratoma, postpubertal-type | **[[Teratoma]], postpubertal-type | ||
**Teratoma with somatic-type | **[[Teratoma]] with somatic-type | ||
*Non-seminomatous germ cell type tumor of more than one histological type | *Non-seminomatous [[Germ cell tumor|germ cell type tumor]] of more than one [[histological]] type | ||
**Mixed germ cell tumors | **[[Germ cell tumors|Mixed germ cell tumors]] | ||
*Germ cell tumors of unknown type | *[[Germ cell tumors]] of unknown type | ||
**Regressed germ cell tumors | **Regressed [[germ cell tumors]] | ||
'''Germ cell tumors unrelated to germ cell neoplasia in situ:''' | '''[[Germ cell tumors]] unrelated to [[Germ cell neoplasm|germ cell neoplasia]] [[in situ]]:''' | ||
*Spermatocytic tumor | *Spermatocytic [[tumor]] | ||
*Teratoma, prepubertal-type | *[[Teratoma]], prepubertal-type | ||
**Dermoid cyst | **[[Dermoid cyst]] | ||
**Epidermoid cyst | **[[Epidermoid cyst]] | ||
**Well-differentiated neuroendocrine tumor (monodermal teratoma) | **Well-differentiated [[neuroendocrine]] [[tumor]] ([[monodermal teratoma]]) | ||
*Mixed teratoma and yolk sac tumor, prepubertal-type | *Mixed [[teratoma]] and [[yolk sac tumor]], prepubertal-type | ||
*Yolk sac tumor, prepubertal-type | *[[Yolk sac tumor]], prepubertal-type | ||
| | | | ||
*Pure tumors | *Pure [[tumors]] | ||
*Leydig cell tumor | *[[Leydig cell tumor]] | ||
**Malignant leydig cell tumor | **[[Leydig cell tumor|Malignant leydig cell tumor]] | ||
*Sertoli cell tumor | *[[Sertoli cell|Sertoli cell tumor]] | ||
**Malignant Sertoli cell tumor | **[[Malignant]] [[Sertoli cell]] [[tumor]] | ||
**Large cell calcifying Sertoli cell tumor | **[[Large cell]] calcifying [[Sertoli cell]] [[tumor]] | ||
**Intratubular large cell hyalinizing Sertoli cell neoplasia | **Intratubular large cell hyalinizing [[Sertoli cell]] [[neoplasia]] | ||
*Granulosa cell tumor | *[[Granulosa cell tumor]] | ||
**Adult granulosa cell tumor | **[[Granulosa cell tumor|Adult granulosa cell tumor]] | ||
**Juvenile granulosa cell tumor | **[[Granulosa cell tumor|Juvenile granulosa cell tumor]] | ||
*Tumors in the fibroma-thecoma group | *[[Tumors]] in the [[fibroma]]-[[thecoma]] group | ||
*Mixed and unclassified sex-stromal tumors | *Mixed and unclassified sex-[[Stromal|stromal tumors]] | ||
*Mixed sex cord-stromal tumor | *Mixed [[sex cord-stromal tumor]] | ||
*Unclassified sex cord-stromal tumor | *Unclassified [[sex cord-stromal tumor]] | ||
|'''Ovarian epithelial-type tumors''' | |'''[[Ovarian]] epithelial-type tumors''' | ||
*Serous cystadenoma | *[[Serous]] cystadenoma | ||
*Serous tumor of borderline malignancy | *Serous [[tumor]] of borderline [[malignancy]] | ||
*Serous cystadenocarcinoma | *Serous cystadenocarcinoma | ||
*Mucinous borderline tumor | *[[Mucinous]] borderline [[tumor]] | ||
*Mucinous cystadenocarcinoma | *Mucinous cystadenocarcinoma | ||
*Endometrioid adenocarcinoma | *[[Endometrioid tumor|Endometrioid]] [[adenocarcinoma]] | ||
*Clear cell adenocarcinoma | *[[Adenocarcinoma|Clear cell adenocarcinoma]] | ||
*Brenner tumor | *Brenner tumor | ||
'''Juvenile Xanthogranuloma''' | '''Juvenile Xanthogranuloma''' | ||
'''Hemangioma''' | '''Hemangioma''' | ||
| | | | ||
*Diffuse large B-cell lymphoma | *[[Diffuse large B-cell lymphoma]] | ||
*Follicular lymphoma, NOS | *[[Follicular lymphoma]], NOS | ||
*Extranodal NK/T-cell lymphoma, nasal type | *[[Extranodal NK-T-cell lymphoma|Extranodal]] [[Lymphoma|NK/T-cell lymphoma]], nasal type | ||
*Plasmacytoma | *[[Plasmacytoma]] | ||
*Myeloid sarcoma | *[[Myeloid]] [[sarcoma]] | ||
*Rosai-Dorfman disease | *[[Rosai-Dorfman disease]] | ||
| | | | ||
*Adenoma | *[[Adenoma]] | ||
*Adenocarcinoma | *[[Adenocarcinoma]] | ||
| | | | ||
*Gonadoblastoma | *[[Gonadoblastoma]] | ||
|} | |} | ||
Latest revision as of 16:19, 28 May 2019
Testicular cancer Microchapters |
Diagnosis |
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Treatment |
Case Studies |
Testicular cancer classification On the Web |
American Roentgen Ray Society Images of Testicular cancer classification |
Risk calculators and risk factors for Testicular cancer classification |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Gertrude Djouka, M.D.[2], Shanshan Cen, M.D. [3]
Overview
Testicular cancer is a very rare type of cancer. Based on the histopathological features, testicular cancer may be classified into six subtypes: germ cell tumors, sex-cord stromal tumors, tumors containing both germ cell and sex-cord stromal elements, miscellaneous tumors of the testis, hematolymphoid tumors, and tumors of collecting duct and rete testis.
Classification
WHO Classification of testicular Tumors
WHO classifies testicular tumors as follows:[1][2]
Testicular Cancer | |||||
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Germ cell tumors | Sex-cord stromal tumors | Miscellaneous tumors of the testis | Hematolymphoid tumors | Tumors of collecting duct and rete testis | Tumors containing both germ cell and sex-cord stromal elements |
Germ cell tumors derived from germ cell neoplasia in situ:
Germ cell tumors unrelated to germ cell neoplasia in situ:
|
|
Ovarian epithelial-type tumors
Juvenile Xanthogranuloma Hemangioma |
References
- ↑ Williamson SR, Delahunt B, Magi-Galluzzi C, Algaba F, Egevad L, Ulbright TM, Tickoo SK, Srigley JR, Epstein JI, Berney DM (February 2017). "The World Health Organization 2016 classification of testicular germ cell tumours: a review and update from the International Society of Urological Pathology Testis Consultation Panel". Histopathology. 70 (3): 335–346. doi:10.1111/his.13102. PMID 27747907.
- ↑ Moch H, Cubilla AL, Humphrey PA, Reuter VE, Ulbright TM (July 2016). "The 2016 WHO Classification of Tumours of the Urinary System and Male Genital Organs-Part A: Renal, Penile, and Testicular Tumours". Eur. Urol. 70 (1): 93–105. doi:10.1016/j.eururo.2016.02.029. PMID 26935559.