Testicular cancer history and symptoms: Difference between revisions
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==Overview== | ==Overview== | ||
The most common symptoms of testicular cancer include a painless [[lump]] in the [[testicle]], [[swelling]] of the testicle, and [[weight loss]]. | The most common [[symptoms]] of testicular cancer include a painless [[lump]] in the [[testicle]], [[swelling]] of the [[Testicles|testicle]], and [[weight loss]]. | ||
==History and Symptoms== | ==History and Symptoms== | ||
===Common Symptoms=== | ===Common Symptoms=== | ||
Common symptoms of testicular cancer include:<ref name="MotzerAgarwal2012">{{cite journal|last1=Motzer|first1=Robert J.|last2=Agarwal|first2=Neeraj|last3=Beard|first3=Clair|last4=Bhayani|first4=Sam|last5=Bolger|first5=Graeme B.|last6=Buyyounouski|first6=Mark K.|last7=Carducci|first7=Michael A.|last8=Chang|first8=Sam S.|last9=Choueiri|first9=Toni K.|last10=Gupta|first10=Shilpa|last11=Hancock|first11=Steven L.|last12=Hudes|first12=Gary R.|last13=Jonasch|first13=Eric|last14=Kuzel|first14=Timothy M.|last15=Lau|first15=Clayton|last16=Levine|first16=Ellis G.|last17=Lin|first17=Daniel W.|last18=Margolin|first18=Kim A.|last19=Michaelson|first19=M. Dror|last20=Olencki|first20=Thomas|last21=Pili|first21=Roberto|last22=Ratliff|first22=Thomas W.|last23=Redman|first23=Bruce G.|last24=Robertson|first24=Cary N.|last25=Ryan|first25=Charles J.|last26=Sheinfeld|first26=Joel|last27=Wang|first27=Jue|last28=Wilder|first28=Richard B.|title=Testicular Cancer|journal=Journal of the National Comprehensive Cancer Network|volume=10|issue=4|year=2012|pages=502–535|issn=1540-1405|doi=10.6004/jnccn.2012.0050}}</ref><ref name="pmid9227931">{{cite journal |vauthors=Bosl GJ, Motzer RJ |title=Testicular germ-cell cancer |journal=N. Engl. J. Med. |volume=337 |issue=4 |pages=242–53 |date=July 1997 |pmid=9227931 |doi=10.1056/NEJM199707243370406 |url=}}</ref> | Common [[symptoms]] of testicular cancer include:<ref name="MotzerAgarwal2012">{{cite journal|last1=Motzer|first1=Robert J.|last2=Agarwal|first2=Neeraj|last3=Beard|first3=Clair|last4=Bhayani|first4=Sam|last5=Bolger|first5=Graeme B.|last6=Buyyounouski|first6=Mark K.|last7=Carducci|first7=Michael A.|last8=Chang|first8=Sam S.|last9=Choueiri|first9=Toni K.|last10=Gupta|first10=Shilpa|last11=Hancock|first11=Steven L.|last12=Hudes|first12=Gary R.|last13=Jonasch|first13=Eric|last14=Kuzel|first14=Timothy M.|last15=Lau|first15=Clayton|last16=Levine|first16=Ellis G.|last17=Lin|first17=Daniel W.|last18=Margolin|first18=Kim A.|last19=Michaelson|first19=M. Dror|last20=Olencki|first20=Thomas|last21=Pili|first21=Roberto|last22=Ratliff|first22=Thomas W.|last23=Redman|first23=Bruce G.|last24=Robertson|first24=Cary N.|last25=Ryan|first25=Charles J.|last26=Sheinfeld|first26=Joel|last27=Wang|first27=Jue|last28=Wilder|first28=Richard B.|title=Testicular Cancer|journal=Journal of the National Comprehensive Cancer Network|volume=10|issue=4|year=2012|pages=502–535|issn=1540-1405|doi=10.6004/jnccn.2012.0050}}</ref><ref name="pmid9227931">{{cite journal |vauthors=Bosl GJ, Motzer RJ |title=Testicular germ-cell cancer |journal=N. Engl. J. Med. |volume=337 |issue=4 |pages=242–53 |date=July 1997 |pmid=9227931 |doi=10.1056/NEJM199707243370406 |url=}}</ref> | ||
* Painless [[lump]] in the [[testicle]] (pathognomonic of the testicular cancer) | * Painless [[lump]] in the [[testicle]] (pathognomonic of the testicular cancer) | ||
* [[Swelling]] of the testicle | * [[Swelling]] of the [[Testicles|testicle]] | ||
* Feeling of heaviness in the [[scrotum]] or [[abdomen]] | * Feeling of heaviness in the [[scrotum]] or [[abdomen]] | ||
* [[Lymphadenopathy]] | * [[Lymphadenopathy]] | ||
| Line 25: | Line 25: | ||
* [[Hemoptysis]] | * [[Hemoptysis]] | ||
* [[Chest pain]] | * [[Chest pain]] | ||
===Leydig cell tumors=== | |||
*[[Testicular mass]] | |||
*[[Endocrine]] involvement such as:<ref name="pmid18660859">{{cite journal| author=Tazi MF, Mellas S, El Fassi MJ, Farih MH| title=Leydig cell hyperplasia revealed by gynecomastia. | journal=Rev Urol | year= 2008 | volume= 10 | issue= 2 | pages= 164-7 | pmid=18660859 | doi= | pmc=2483322 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18660859 }}</ref><ref name="pmid2024387">{{cite journal| author=Dilworth JP, Farrow GM, Oesterling JE| title=Non-germ cell tumors of testis. | journal=Urology | year= 1991 | volume= 37 | issue= 5 | pages= 399-417 | pmid=2024387 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=2024387 }}</ref> | |||
**[[Gynecomastia]] in both prepubertal and adult [[patients]] | |||
**Loss of [[fertility]] and [[libido]] in aldult [[patients]] | |||
**[[Precocious Puberty|Precocious]] [[virilization]] in infants | |||
**Loss of [[body]] [[hair]] | |||
**[[Areola]] [[hyperpigmentation]] | |||
===Sertoli cell tumors=== | |||
*[[Scrotal mass|Scrotal]] [[mass]] | |||
*[[Gynecomastia]] in [[pediatric]] population<ref name="pmid7003168">{{cite journal| author=Gabrilove JL, Freiberg EK, Leiter E, Nicolis GL| title=Feminizing and non-feminizing Sertoli cell tumors. | journal=J Urol | year= 1980 | volume= 124 | issue= 6 | pages= 757-67 | pmid=7003168 | doi=10.1016/s0022-5347(17)55652-9 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=7003168 }}</ref> | |||
==References== | ==References== | ||
Latest revision as of 10:45, 1 July 2019
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Gertrude Djouka, M.D.[2], Shanshan Cen, M.D. [3]
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Overview
The most common symptoms of testicular cancer include a painless lump in the testicle, swelling of the testicle, and weight loss.
History and Symptoms
Common Symptoms
Common symptoms of testicular cancer include:[1][2]
- Painless lump in the testicle (pathognomonic of the testicular cancer)
- Swelling of the testicle
- Feeling of heaviness in the scrotum or abdomen
- Lymphadenopathy
- Pain in the back or abdomen
- Ascites
- Weight loss
- Gynecomastia
- Precocious Puberty
- Infertility
Less Common Symptoms
Leydig cell tumors
- Testicular mass
- Endocrine involvement such as:[3][4]
- Gynecomastia in both prepubertal and adult patients
- Loss of fertility and libido in aldult patients
- Precocious virilization in infants
- Loss of body hair
- Areola hyperpigmentation
Sertoli cell tumors
- Scrotal mass
- Gynecomastia in pediatric population[5]
References
- ↑ Motzer, Robert J.; Agarwal, Neeraj; Beard, Clair; Bhayani, Sam; Bolger, Graeme B.; Buyyounouski, Mark K.; Carducci, Michael A.; Chang, Sam S.; Choueiri, Toni K.; Gupta, Shilpa; Hancock, Steven L.; Hudes, Gary R.; Jonasch, Eric; Kuzel, Timothy M.; Lau, Clayton; Levine, Ellis G.; Lin, Daniel W.; Margolin, Kim A.; Michaelson, M. Dror; Olencki, Thomas; Pili, Roberto; Ratliff, Thomas W.; Redman, Bruce G.; Robertson, Cary N.; Ryan, Charles J.; Sheinfeld, Joel; Wang, Jue; Wilder, Richard B. (2012). "Testicular Cancer". Journal of the National Comprehensive Cancer Network. 10 (4): 502–535. doi:10.6004/jnccn.2012.0050. ISSN 1540-1405.
- ↑ Bosl GJ, Motzer RJ (July 1997). "Testicular germ-cell cancer". N. Engl. J. Med. 337 (4): 242–53. doi:10.1056/NEJM199707243370406. PMID 9227931.
- ↑ Tazi MF, Mellas S, El Fassi MJ, Farih MH (2008). "Leydig cell hyperplasia revealed by gynecomastia". Rev Urol. 10 (2): 164–7. PMC 2483322. PMID 18660859.
- ↑ Dilworth JP, Farrow GM, Oesterling JE (1991). "Non-germ cell tumors of testis". Urology. 37 (5): 399–417. PMID 2024387.
- ↑ Gabrilove JL, Freiberg EK, Leiter E, Nicolis GL (1980). "Feminizing and non-feminizing Sertoli cell tumors". J Urol. 124 (6): 757–67. doi:10.1016/s0022-5347(17)55652-9. PMID 7003168.