Uveal melanoma MRI: Difference between revisions

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Latest revision as of 18:11, 14 August 2019

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Fahimeh Shojaei, M.D.

Overview

MRI may be helpful in the diagnosis of uveal melanoma. Findings on MRI suggestive of uveal melanoma include high intensity mass lesion (due to melanin and hemorrhage) on T1, and low intensity mass lesion on T2. The lesion enhances with gadolinium.

MRI

MRI may be helpful in the diagnosis of uveal melanoma. Findings on MRI suggestive of uveal melanoma include:

High intensity mass lesion (due to melanin and hemorrhage) on T1
Low intensity mass lesion on T2
The lesion enhances with gadolinium

Iris/ ciliary body melanoma

Case courtesy of Dr Dalia Ibrahim, <a href="https://radiopaedia.org/">Radiopaedia.org</a>. From the case <a href="https://radiopaedia.org/cases/31362">rID: 31362</a>

Chroida; melanoma

Case courtesy of Dr Ammar Haouimi, <a href="https://radiopaedia.org/">Radiopaedia.org</a>. From the case <a href="https://radiopaedia.org/cases/60192">rID: 60192</a>

References

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 __NOTOC__
 {{Uveal melanoma}}
-{{CMG}}{{AE}}{{Simrat}}
+{{CMG}}{{AE}} {{Fs}}
 ==Overview==
-Head and neck MRI may be helpful in the diagnosis of uveal melanoma. Head and neck MRI scan is diagnostic of uveal melanoma. On [[head]] and [[neck]] [[MRI]], uveal melanoma is characterized by isointense to hypointense mass on T1-weighted MRI and hyperintense mass on T2-weighted MRI.<ref name="radio">  Retinoblastoma. Radiopedia(2015) http://radiopaedia.org/articles/primary-uveal-malignant-melanoma Accessed on October 21, 2015</ref>
+[[MRI]] may be helpful in the [[diagnosis]] of uveal melanoma. Findings on [[MRI]] suggestive of uveal melanoma include high intensity [[mass]] [[lesion]] (due to [[melanin]] and [[hemorrhage]]) on [[T1]], and low intensity [[mass]] lesion on T2. The [[lesion]] enhances with [[gadolinium]].
 ==MRI==
-MRI is the modality of choice for assessment of malignant uveal melanomas 5-6.
-T1 or PD
-uveal melanomas are seen as moderately high signal mass lesion
-associated exudative retinal detachment is moderately high signal
-T2
-moderately low signal mass lesion
-associated exudative retinal detachment is moderately high signal
-haemorrhagic subretinal fluid has variable signal pattern
-T1 C+ (Gd)
-tumours enhance
-fat suppression useful in detecting extraocular extention
-[[MRI]] is the modality of choice for pre-treatment staging on retinoblastoma.
-*The MRI features of retinoblastoma include:<ref name="radio">  Retinoblastoma. Radiopedia(2015) http://radiopaedia.org/articles/retinoblastoma Accessed on October 10, 2015</ref>
-{| style="border: 0px; font-size: 90%; margin: 3px; width: 600px" align=center
-|valign=top|
-|+
-! style="background: #4479BA; width: 200px;" | {{fontcolor|#FFF|MRI component}}
-! style="background: #4479BA; width: 400px;" | {{fontcolor|#FFF|Features}}
-|-
-| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |
-:T1
-| style="padding: 5px 5px; background: #F5F5F5;" |
-*Intermediate signal intensity, hyperintense c.f. vitreous
-|-
-| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |
-:T2
-| style="padding: 5px 5px; background: #F5F5F5;" |
-*Hypointense c.f. vitreous
-|-
-| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |
-:T1 contrast with gadolinium
-| style="padding: 5px 5px; background: #F5F5F5;" |
-*The mass usually enhances relatively homogeneously when small
-*Larger tumors often have areas of necrosis, rendering it heterogeneous
-*Linear enhancement of the choroid beyond the margins of the tumour should raise the possibility of choroidal involvement, although inflammation may lead to similar appearance
-*Enhancement of the anterior chamber need not represent tumour involvement, with hyperaemia, uveitis and iris neovascularisation all leading to asymmetric enhancement
-*Careful assessment of the optic disc and optic nerve should be carried out to assess for involvement
-*Extra-ocular extension through the sclera will be visible as interruption of the otherwise hypointense non-enhancing sclera by enhancing tumour
-|-
-| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |
-:Diffusion Weighted Imaging
-| style="padding: 5px 5px; background: #F5F5F5;" |
-*The tumour shows restricted diffusion on DWI at high b values. It exhibits low ADC values in contrast to the high intensity of the vitreous in the ADC maps
-*ADC map can be used to differentiate viable and necrotic tumour
-*DWI is valuable in evaluating the response to eye-preservation treatment
-|-
-|}
+[[MRI]] may be helpful in the [[diagnosis]] of uveal melanoma. Findings on [[MRI]] suggestive of uveal melanoma include:
+* High intensity [[mass]] [[lesion]] (due to [[melanin]] and [[hemorrhage]]) on T1
+* Low intensity [[mass]] [[lesion]] on T2
+* The lesion enhances with [[gadolinium]]
+=== Iris/ ciliary body melanoma ===
+[[File:5af151cc86aa97d54c3897001c7e60 big gallery.jpg|400px|none|thumb|Case courtesy of Dr Dalia Ibrahim, <a href="https://radiopaedia.org/">Radiopaedia.org</a>. From the case <a href="https://radiopaedia.org/cases/31362">rID: 31362</a>]]<br />
+=== Chroida; melanoma ===
+[[File:50e2182c105bc220b390fefd13fb16 big gallery.jpeg|400px|none|thumb|Case courtesy of Dr Ammar Haouimi, <a href="https://radiopaedia.org/">Radiopaedia.org</a>. From the case <a href="https://radiopaedia.org/cases/60192">rID: 60192</a>]]
+<br />
 ==References==
 {{reflist|2}}
 {{WikiDoc Help Menu}}
 {{WikiDoc Sources}}
 [[Category:Disease]]
+[[Category:Ophthalmology]]
+ [[Category:Up-To-Date]]
+[[Category:Oncology]]
+[[Category:Medicine]]
 [[Category:Ophthalmology]]