Gliomatosis cerebri MRI: Difference between revisions

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==Overview==
==Overview==
 
Brain MRI is helpful in the diagnosis of gliomatosis cerebri. On brain MRI, gliomatosis cerebri is characterized by bilateral and diffuse infiltrative tumor which is isointense or hypointense on T1-weighted images and hyperintense on T2-weighted and FLAIR images.
==MRI==
==MRI==
 
Brain MRI is helpful in the diagnosis of gliomatosis cerebri. On brain MRI, gliomatosis cerebri is characterized by:<ref name="ddd">Radiographic features of gliomatosis cerebri. Dr Henry Knipe and Dr Frank Gaillard et al. Radiopaedia 2015. http://radiopaedia.org/articles/gliomatosis-cerebri</ref><ref name="pmid9075253">{{cite journal| author=Onal C, Bayindir C, Siraneci R, Izgi N, Yalçin I, Altinel Z et al.| title=A serial CT scan and MRI verification of diffuse cerebrospinal gliomatosis: a case report with stereotactic diagnosis and radiological confirmation. | journal=Pediatr Neurosurg | year= 1996 | volume= 25 | issue= 2 | pages= 94-9 | pmid=9075253 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9075253  }} </ref><br>
 
Brain MRI is helpful in the diagnosis of gliomatosis cerebri. On brain MRI, gliomatosis cerebri is characterized by:<ref name=ddd>Radiographic features of gliomatosis cerebri. Dr Henry Knipe and Dr Frank Gaillard et al. Radiopaedia 2015. http://radiopaedia.org/articles/gliomatosis-cerebri</ref>
 
{| style="border: 0px; font-size: 90%; margin: 3px; width: 600px" align=center
{| style="border: 0px; font-size: 90%; margin: 3px; width: 600px" align=center
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! style="background: #4479BA; width: 400px;" | {{fontcolor|#FFF|Findings}}
! style="background: #4479BA; width: 400px;" | {{fontcolor|#FFF|Findings}}
|-
|-
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |
! style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |
T1
T1
| style="padding: 5px 5px; background: #F5F5F5;" |
| style="padding: 5px 5px; background: #F5F5F5;" |
*Iso to hypointense to grey matter
*Iso to hypointense to grey matter
|-
|-
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |
! style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |
T2
T2
| style="padding: 5px 5px; background: #F5F5F5;" |
| style="padding: 5px 5px; background: #F5F5F5;" |
*Hyperintense to grey matter
*Hyperintense to grey matter
|-
|-
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |
! style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |
T1C+
T1 with contrast
| style="padding: 5px 5px; background: #F5F5F5;" |
| style="padding: 5px 5px; background: #F5F5F5;" |
*No or minimal enhancement
*No or minimal enhancement
|-
|-
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |
! style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |
DWI
Diffusion weighted imaging
| style="padding: 5px 5px; background: #F5F5F5;" |  
| style="padding: 5px 5px; background: #F5F5F5;" |  
*No restriction
*No restriction
|-
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |
MR spectroscopy
| style="padding: 5px 5px; background: #F5F5F5;" |
*E​levated [[choline]]/[[creatine]] and [[choline]]/NAA ratios
*Marked elevation of myo-inositol
|-
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |
MR perfusion
| style="padding: 5px 5px; background: #F5F5F5;" |
*​Low/normal rCBV
*Correlates with no vascular hyperplasia
|}
|}
 
<br>
 
===Gallery===
[[file:Axial FLAIR Gliomatosis cerebri.jpg| Thumb|none|250px]] Axial FLAIR gliomatosis cerebri MRI.<ref>Image courtesy of  Dr. Henry Knipe and Dr. Frank Gaillard et al. [http://www.radiopaedia.org Radiopaedia] (original file [http://radiopaedia.org/articles/gliomatosis-cerebri ''here']).[http://radiopaedia.org/licence Creative Commons BY-SA-NC]</ref>
<gallery>
[[File:T1 Gliomatosis cerebri.jpg| thumb|none|250px]] T1 MRI of gliomatosis cerebri.<ref>Image courtesy of  Dr. Henry Knipe and Dr. Frank Gaillard et al. [http://www.radiopaedia.org Radiopaedia] (original file [http://radiopaedia.org/articles/gliomatosis-cerebri ''here']).[http://radiopaedia.org/licence Creative Commons BY-SA-NC]</ref>
Image:Axial FLAIR Gliomatosis cerebri.jpg|Axial FLAIR gliomatosis cerebri MRI.<ref name=zzz>Image courtesy of  Dr. Henry Knipe and Dr. Frank Gaillard et al. [http://www.radiopaedia.org Radiopaedia] (original file [http://radiopaedia.org/articles/gliomatosis-cerebri ''here']).[http://radiopaedia.org/licence Creative Commons BY-SA-NC]</ref>  
Image:T1 Gliomatosis cerebri.jpg|T1 MRI of gliomatosis cerebri.<ref name=zzz>Image courtesy of  Dr. Henry Knipe and Dr. Frank Gaillard et al. [http://www.radiopaedia.org Radiopaedia] (original file [http://radiopaedia.org/articles/gliomatosis-cerebri ''here']).[http://radiopaedia.org/licence Creative Commons BY-SA-NC]</ref>
Image:Coronal T2 Gliomatosis cerebri.jpg|Coronal T2 gliomatosis cerebri MRI.<ref name=zzz>Image courtesy of  Dr. Henry Knipe and Dr. Frank Gaillard et al. [http://www.radiopaedia.org Radiopaedia] (original file [http://radiopaedia.org/articles/gliomatosis-cerebri ''here']).[http://radiopaedia.org/licence Creative Commons BY-SA-NC]</ref>
Image:T2 MRI gliomatosis cerebri.jpg|T2 MRI of gliomatosis cerebri.<ref name=zzz>Image courtesy of  Dr. Henry Knipe and Dr. Frank Gaillard et al. [http://www.radiopaedia.org Radiopaedia] (original file [http://radiopaedia.org/articles/gliomatosis-cerebri ''here']).[http://radiopaedia.org/licence Creative Commons BY-SA-NC]</ref>
Image:Axial T1.jpg|Axial T1 MRI of gliomatosis cerebri.<ref name=zzz>Image courtesy of  Dr. Henry Knipe and Dr. Frank Gaillard et al. [http://www.radiopaedia.org Radiopaedia] (original file [http://radiopaedia.org/articles/gliomatosis-cerebri ''here']).[http://radiopaedia.org/licence Creative Commons BY-SA-NC]</ref>
Image:Axial ADC.jpg|Axial ADC of gliomatosis cerebri.<ref name=zzz>Image courtesy of  Dr. Henry Knipe and Dr. Frank Gaillard et al. [http://www.radiopaedia.org Radiopaedia] (original file [http://radiopaedia.org/articles/gliomatosis-cerebri ''here']).[http://radiopaedia.org/licence Creative Commons BY-SA-NC]</ref>
Image:MR spectroscopy.jpg|MR spectroscopy of gliomatosis cerebri.<ref name=zzz>Image courtesy of  Dr. Henry Knipe and Dr. Frank Gaillard et al. [http://www.radiopaedia.org Radiopaedia] (original file [http://radiopaedia.org/articles/gliomatosis-cerebri ''here']).[http://radiopaedia.org/licence Creative Commons BY-SA-NC]</ref>
</gallery>


==References==
==References==
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Latest revision as of 16:41, 7 October 2019

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]

Overview

Brain MRI is helpful in the diagnosis of gliomatosis cerebri. On brain MRI, gliomatosis cerebri is characterized by bilateral and diffuse infiltrative tumor which is isointense or hypointense on T1-weighted images and hyperintense on T2-weighted and FLAIR images.

MRI

Brain MRI is helpful in the diagnosis of gliomatosis cerebri. On brain MRI, gliomatosis cerebri is characterized by:[1][2]
MRI component Findings

T1

  • Iso to hypointense to grey matter

T2

  • Hyperintense to grey matter

T1 with contrast

  • No or minimal enhancement

Diffusion weighted imaging

  • No restriction


Gallery

  • Axial FLAIR gliomatosis cerebri MRI.[3]
    Axial FLAIR gliomatosis cerebri MRI.[3]
  • T1 MRI of gliomatosis cerebri.[3]
    T1 MRI of gliomatosis cerebri.[3]
  • Coronal T2 gliomatosis cerebri MRI.[3]
    Coronal T2 gliomatosis cerebri MRI.[3]
  • T2 MRI of gliomatosis cerebri.[3]
    T2 MRI of gliomatosis cerebri.[3]
  • Axial T1 MRI of gliomatosis cerebri.[3]
    Axial T1 MRI of gliomatosis cerebri.[3]
  • Axial ADC of gliomatosis cerebri.[3]
    Axial ADC of gliomatosis cerebri.[3]
  • MR spectroscopy of gliomatosis cerebri.[3]
    MR spectroscopy of gliomatosis cerebri.[3]

References

  1. ↑ Radiographic features of gliomatosis cerebri. Dr Henry Knipe and Dr Frank Gaillard et al. Radiopaedia 2015. http://radiopaedia.org/articles/gliomatosis-cerebri
  2. ↑ Onal C, Bayindir C, Siraneci R, Izgi N, Yalçin I, Altinel Z; et al. (1996). "A serial CT scan and MRI verification of diffuse cerebrospinal gliomatosis: a case report with stereotactic diagnosis and radiological confirmation". Pediatr Neurosurg. 25 (2): 94–9. PMID 9075253.
  3. ↑ 3.0 3.1 3.2 3.3 3.4 3.5 3.6 Image courtesy of Dr. Henry Knipe and Dr. Frank Gaillard et al. Radiopaedia (original file here').Creative Commons BY-SA-NC


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