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{{Subependymal giant cell astrocytoma}}
{{Subependymal giant cell astrocytoma}}
{{CMG}}{{AE}}{{SR}}
{{CMG}}, {{AE}}{{IO}}, {{SR}}


==Overview==
==Overview==
On head [[Computed tomography|CT]], some of the findings that are suggestive of subependymal giant cell astrocytoma include a heterogenous [[mass]] with uniform post [[contrast]] enhancement, enlargement of the ventricles, and iso- or slightly hypoattenuating to [[grey matter]].


==CT==
==CT==
Head CT scan may be helpful in the diagnosis of subependymal giant cell astrocytoma. On head CT scan, subependymal giant cell astrocytoma is characterized by:<ref name=CTfindings1>Radiographic CT features of subependymal giant cell astrocytoma. Dr Bruno Di Muzio and Dr Jeremy Jones et al. Radiopaedia 2015. http://radiopaedia.org/articles/subependymal-giant-cell-astrocytoma. Accessed on November 4, 2015</ref>
Head [[Computed tomography|CT scan]] may be helpful in the [[diagnosis]] of subependymal giant cell astrocytoma. Findings on [[Computed tomography|CT scan]] suggestive of/diagnostic of subependymal giant cell astrocytoma include:<ref name="pmid25977907">{{cite journal| author=Jung TY, Kim YH, Jung S, Baek HJ, Lee KH| title=The clinical characteristics of subependymal giant cell astrocytoma: five cases. | journal=Brain Tumor Res Treat | year= 2015 | volume= 3 | issue= 1 | pages= 44-7 | pmid=25977907 | doi=10.14791/btrt.2015.3.1.44 | pmc=4426277 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25977907  }} </ref><ref name="pmid26942030">{{cite journal| author=Stein JR, Reidman DA| title=Imaging Manifestations of a Subependymal Giant Cell Astrocytoma in Tuberous Sclerosis. | journal=Case Rep Radiol | year= 2016 | volume= 2016 | issue=  | pages= 3750450 | pmid=26942030 | doi=10.1155/2016/3750450 | pmc=4752974 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26942030  }} </ref><ref name="pmid3791849">{{cite journal| author=Moran V, O'Keeffe F| title=Giant cell astrocytoma in tuberous sclerosis: computed tomographic findings. | journal=Clin Radiol | year= 1986 | volume= 37 | issue= 6 | pages= 543-5 | pmid=3791849 | doi=10.1016/s0009-9260(86)80009-5 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=3791849  }} </ref><ref name="BeaumontGodzik2015">{{cite journal|last1=Beaumont|first1=Thomas L.|last2=Godzik|first2=Jakub|last3=Dahiya|first3=Sonika|last4=Smyth|first4=Matthew D.|title=Subependymal giant cell astrocytoma in the absence of tuberous sclerosis complex: case report|journal=Journal of Neurosurgery: Pediatrics|volume=16|issue=2|year=2015|pages=134–137|issn=1933-0707|doi=10.3171/2015.1.PEDS13146}}</ref>
*Intraventricular mass near the [[foramen of Monro]]
*Round, heterogeneous [[mass]]
*Usually larger than 1 cm
*Uniform post-[[contrast]] enhancement
*Iso- or slightly hypoattenuating to grey matter
*[[Cyst]]
*[[Calcification]] is common
*[[Calcification]]
*[[Hemorrhage]]
*Iso- or slightly hypoattenuating to [[grey matter]]
*Accompanying [[hydrocephalus]] may be present
*Enlargement of the ventricles
*Marked contrast enhancement
*Perilesional [[edema]]


==Gallery==
[[File:SEGA CT 1.jpg|400px|thumb|left|Axial brain CT scan showing an intraventricular mass in the right foramen of Monro area, with cystic and solid components and small areas of calcification. There is a contrast enhancement of solid component. Also multiple calcified subependymal nodules are seen [https://radiopaedia.org/cases/subependymal-giant-cell-astrocytoma-associated-with-tuberous-sclerosis?lang=us source:Case courtesy of Dr Ilkhom Nalibaev, <a href="https://radiopaedia.org/">Radiopaedia.org</a>. From the case <a href="https://radiopaedia.org/cases/48054">rID: 48054</a> ]]]
<gallery>
<br style="clear:left" />


Image:Subependymal giant cell astrocytoma CT scan 1.jpg|<sub>There is an intraventricular mass in the foramem of Monro area, on the left, with contrast enhancement and irregular calcifications. Multiple subependymal calcified nodules are also seem.<ref name=radioCTsega1>Image courtesy of Dr. Paresh K Desai. Radiopaedia (original file [http://radiopaedia.org/cases/sgca-in-tuberous-sclerosis-3 here]). Creative Commons BY-SA-NC</ref></sub>
==References==
 
{{reflist|2}}
</gallery>
==Reference=={{reflist|2}}


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Latest revision as of 16:47, 7 November 2019

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1], Associate Editor(s)-in-Chief: Ifeoma Odukwe, M.D. [2], Sujit Routray, M.D. [3]

Overview

On head CT, some of the findings that are suggestive of subependymal giant cell astrocytoma include a heterogenous mass with uniform post contrast enhancement, enlargement of the ventricles, and iso- or slightly hypoattenuating to grey matter.

CT

Head CT scan may be helpful in the diagnosis of subependymal giant cell astrocytoma. Findings on CT scan suggestive of/diagnostic of subependymal giant cell astrocytoma include:[1][2][3][4]

Axial brain CT scan showing an intraventricular mass in the right foramen of Monro area, with cystic and solid components and small areas of calcification. There is a contrast enhancement of solid component. Also multiple calcified subependymal nodules are seen source:Case courtesy of Dr Ilkhom Nalibaev, <a href="https://radiopaedia.org/">Radiopaedia.org</a>. From the case <a href="https://radiopaedia.org/cases/48054">rID: 48054</a>


References

  1. Jung TY, Kim YH, Jung S, Baek HJ, Lee KH (2015). "The clinical characteristics of subependymal giant cell astrocytoma: five cases". Brain Tumor Res Treat. 3 (1): 44–7. doi:10.14791/btrt.2015.3.1.44. PMC 4426277. PMID 25977907.
  2. Stein JR, Reidman DA (2016). "Imaging Manifestations of a Subependymal Giant Cell Astrocytoma in Tuberous Sclerosis". Case Rep Radiol. 2016: 3750450. doi:10.1155/2016/3750450. PMC 4752974. PMID 26942030.
  3. Moran V, O'Keeffe F (1986). "Giant cell astrocytoma in tuberous sclerosis: computed tomographic findings". Clin Radiol. 37 (6): 543–5. doi:10.1016/s0009-9260(86)80009-5. PMID 3791849.
  4. Beaumont, Thomas L.; Godzik, Jakub; Dahiya, Sonika; Smyth, Matthew D. (2015). "Subependymal giant cell astrocytoma in the absence of tuberous sclerosis complex: case report". Journal of Neurosurgery: Pediatrics. 16 (2): 134–137. doi:10.3171/2015.1.PEDS13146. ISSN 1933-0707.


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