Idiopathic pulmonary fibrosis causes: Difference between revisions

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__NOTOC__
__NOTOC__
{{Idiopathic pulmonary fibrosis }}
{{Idiopathic pulmonary fibrosis }}
{{CMG}} {{AE}} Jacquelyne DiTroia
{{CMG}}; {{AE}} {{AEL}}
==Overview==
==Overview==
==Pulmonary Fibrosis Causes==
Common causes of pulmonary fibrosis include autoimmunity, rheumatoid arthritis, scleroderma, tuberculosis, SLE, sarocoidosis, and polymyoisitis. Other causes of pulmonary fibrosis include environmental factors as cigarette smoking and dust exposure.
 
==Causes==
===Common Causes===
===Common Causes===
The most common causes of pulmonary fibrosis are:
The most common causes of pulmonary fibrosis are:<ref name="pmid22365244">{{cite journal| author=Olson AL, Swigris JJ| title=Idiopathic pulmonary fibrosis: diagnosis and epidemiology. | journal=Clin Chest Med | year= 2012 | volume= 33 | issue= 1 | pages= 41-50 | pmid=22365244 | doi=10.1016/j.ccm.2011.12.001 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22365244  }}</ref><ref name="pmid24569614">{{cite journal| author=Williams KJ| title=Gammaherpesviruses and pulmonary fibrosis: evidence from humans, horses, and rodents. | journal=Vet Pathol | year= 2014 | volume= 51 | issue= 2 | pages= 372-84 | pmid=24569614 | doi=10.1177/0300985814521838 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24569614  }}</ref>
*[[Autoimmune diseases]]:
*[[Autoimmune diseases]]:
*[[Rheumatoid arthritis]]
*[[Rheumatoid arthritis]]
Line 15: Line 17:
*[[Polymyositis]]
*[[Polymyositis]]
*[[Dermatomyositis]]
*[[Dermatomyositis]]
*[[Anti-synthetase syndrome]]
*Anti-synthetase syndrome
*[[GERD]] - Gastroesophageal Reflux Disease
*[[Gastroesophageal reflux disease]]
===Environmental Factors===
===Environmental Factors===
*[[Cigarette smoking]]
*Cigarette [[smoke]]
*[[Asbestos]] exposure
*[[Asbestos]] exposure
*[[Silica]] exposure
*[[Silica]] exposure
*[[Coal dust]] exposure
*[[Coal dust]] exposure
*[[Beryllium]] exposure
*[[Beryllium]] exposure
*[[Hard metal dusts]] exposure
*Hard metal dusts exposure
*[[Animal protein]] exposure
*Animal protein exposure
*[[Bacteria]], [[molds]] exposure
*[[Bacteria]], [[mold]] exposure
*[[Radiation]]
*[[Radiation]]


===Drugs===
===Drugs===
*[[lomustine]]
*[[lomustine]]
*[[panitumumab]]
*[[Panitumumab]]
*[[penicillamine]]
*[[Penicillamine]]
*[[rifapentin]]
*[[Rifapentine|Rifapentin]]
*[[methotrexate]] ([[Trexall]])
*[[Methotrexate]] ([[Trexall]])
*[[cyclophosphamide]] ([[Cytoxan]])
*[[Cyclophosphamide]] ([[Cytoxan]])
*[[amiodarone]] ([[Cordarone]]
*[[Amiodarone]] ([[Cordarone]])
*[[Nexterone]], ([[Pacerone]])
*[[Nexterone]] ([[Pacerone]])
*[[propranolol]] ([[Inderol]], [[Innopran]])
*[[Propranolol]] ([[Inderol]], [[Innopran]])
*[[nitrofurantoin]] ([[Macrobid]], [[Macrodantin]])
*[[Nitrofurantoin]] ([[Macrobid]], [[Macrodantin]])
*[[sulfasalazine]] ([[Azulfidine]])     
*[[Sulfasalazine]] ([[Azulfidine]])     


Genetic and Inherited Diseases also make up 10-15% of idiopathic pulmonary fibrosis diagnosis'.
Genetic and Inherited Diseases also make up 10-15% of idiopathic pulmonary fibrosis diagnosis.


===Causes by Organ System===
{| style="width:80%; height:100px" border="1"
| style="width:25%" bgcolor="LightSteelBlue" ; border="1" | '''Cardiovascular'''
| style="width:75%" bgcolor="Beige" ; border="1" | No underlying causes
|-
|- bgcolor="LightSteelBlue"
| '''Chemical / poisoning'''
| bgcolor="Beige" | No underlying causes
|-
|- bgcolor="LightSteelBlue"
| '''Dermatologic'''
| bgcolor="Beige" | No underlying causes
|-
|- bgcolor="LightSteelBlue"
| '''Drug Side Effect'''
| bgcolor="Beige" | [[Methotrexate]], [[Trexall]], [[Cyclophosphamide]], [[Cytoxan]], [[Amiodarone]], [[Cordarone]], [[Nexterone]], [[Pacerone]], [[propranolol]], [[Inderol]], [[Innopran]], [[Nitrofurantoin]], [[Macrobid]], [[Macrodantin]], [[Sulfasalazine]], [[Azulfidine]]
|-
|- bgcolor="LightSteelBlue"
| '''Ear Nose Throat'''
| bgcolor="Beige" | No underlying causes
|-
|- bgcolor="LightSteelBlue"
| '''Endocrine'''
| bgcolor="Beige" | No underlying causes
|-
|- bgcolor="LightSteelBlue"
| '''Environmental'''
| bgcolor="Beige" | Cigarette [[Smoke]], [[Asbestos]], [[silica]], Coal dust, [[Beryllium]], heavy metal dusts, Animal proteins, [[Bacteria]], Molds, [[Radiation]] 
|-
|- bgcolor="LightSteelBlue"
| '''Gastroenterologic'''
| bgcolor="Beige" | [[Gastroesophageal reflux disease]]
|-
|- bgcolor="LightSteelBlue"
| '''Genetic'''
| bgcolor="Beige" | No underlying causes
|-
|- bgcolor="LightSteelBlue"
| '''Hematologic'''
| bgcolor="Beige" | No underlying causes
|-
|- bgcolor="LightSteelBlue"
| '''Iatrogenic'''
| bgcolor="Beige" | No underlying causes
|-
|- bgcolor="LightSteelBlue"
| '''Infectious Disease'''
| bgcolor="Beige" | [[Dermatomyositis]], [[Polymyositis]]
|-
|- bgcolor="LightSteelBlue"
| '''Musculoskeletal / Ortho'''
| bgcolor="Beige" | [[Rheumatoid arthritis]]
|-
|- bgcolor="LightSteelBlue"
| '''Neurologic'''
| bgcolor="Beige" | No underlying causes
|-
|- bgcolor="LightSteelBlue"
| '''Nutritional / Metabolic'''
| bgcolor="Beige" | No underlying causes
|-
|- bgcolor="LightSteelBlue"
| '''Obstetric/Gynecologic'''
| bgcolor="Beige" | No underlying causes
|-
|- bgcolor="LightSteelBlue"
| '''Oncologic'''
| bgcolor="Beige" |No underlying causes
|-
|- bgcolor="LightSteelBlue"
| '''Opthalmologic'''
| bgcolor="Beige" | No underlying causes
|-
|- bgcolor="LightSteelBlue"
| '''Overdose / Toxicity'''
| bgcolor="Beige" | No underlying causes
|-
|- bgcolor="LightSteelBlue"
| '''Psychiatric'''
| bgcolor="Beige" | No underlying causes
|-
|- bgcolor="LightSteelBlue"
| '''Pulmonary'''
| bgcolor="Beige" | [[Tuberculosis]], [[Pneumonia]], [[Anti-synthetase syndrome]]
|-
|- bgcolor="LightSteelBlue"
| '''Renal / Electrolyte'''
| bgcolor="Beige" | No underlying causes
|-
|- bgcolor="LightSteelBlue"
| '''Rheum / Immune / Allergy'''
| bgcolor="Beige" | [[Sarcoidosis]], [[Systemic lupus erythematosus]], [[Rheumatoid arthritis]], Lupus pleuritis
|-
|- bgcolor="LightSteelBlue"
| '''Sexual'''
| bgcolor="Beige" | No underlying causes
|-
|- bgcolor="LightSteelBlue"
| '''Trauma'''
| bgcolor="Beige" | No underlying causes
|-
|- bgcolor="LightSteelBlue"
| '''Urologic'''
| bgcolor="Beige" | No underlying causes
|-
|- bgcolor="LightSteelBlue"
| '''Dental'''
| bgcolor="Beige" | No underlying causes
|-
|- bgcolor="LightSteelBlue"
| '''Miscellaneous'''
| bgcolor="Beige" | No underlying causes
|-
|}


===Causes in Alphabetical Order===
{{columns-list|
*[[Amiodarone]]
*Animal protein exposure
*[[Anti-synthetase syndrome]]
*[[Asbestos]]
*[[Autoimmune diseases]]
*[[Azulfidine]]
*[[Bacteria]]
*[[Beryllium]]
*Cigarette [[smoke]]
*[[Coal]] dust exposure
*[[Cordarone]]
*[[Cyclophosphamide]]
*[[Cytoxan]]
*[[Dermatomyositis]]
*[[Gastroesophageal reflux disease]]
*Heavy metal dusts exposure
*Inderol
*Innopran
*[[lomustine]]
*[[Macrobid]]
*[[Macrodantin]]
*[[Methotrexate]]
*[[Mold]]
*Nexterone
*[[Nitrofurantoin]]
*[[Pacerone]]
*[[Panitumumab]]
*[[Penicillamine]]
*[[Pneumonia]]
*[[Polymyositis]]
*[[Propranolol]]
*[[Radiation]]
*[[Rheumatoid arthritis]]
*[[Rifapentine adverse reactions|Rifapentin]]
*[[Sarcoidosis]]
*[[Scleroderma]]
*[[Silica]] exposure
*[[sulfasalazine]]
*[[Systemic lupus erythematosus]]
*[[systemic sclerosis]]
*[[Trexall]]
*[[Tuberculosis]]
}}
==References==
==References==
{{reflist|2}}
{{reflist|2}}
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[[Category:Pulmonology]]
[[Category:Pulmonology]]
[[Category:Disease]]
[[Category:Medicine]]
 
[[Category:Up-To-Date]]
[[Category:Needs content]]
[[Category:Primary Care]

Latest revision as of 21:23, 10 January 2020

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmed Elsaiey, MBBCH [2]

Overview

Common causes of pulmonary fibrosis include autoimmunity, rheumatoid arthritis, scleroderma, tuberculosis, SLE, sarocoidosis, and polymyoisitis. Other causes of pulmonary fibrosis include environmental factors as cigarette smoking and dust exposure.

Causes

Common Causes

The most common causes of pulmonary fibrosis are:[1][2]

Environmental Factors

Drugs

Genetic and Inherited Diseases also make up 10-15% of idiopathic pulmonary fibrosis diagnosis.

Causes by Organ System

Cardiovascular No underlying causes
Chemical / poisoning No underlying causes
Dermatologic No underlying causes
Drug Side Effect Methotrexate, Trexall, Cyclophosphamide, Cytoxan, Amiodarone, Cordarone, Nexterone, Pacerone, propranolol, Inderol, Innopran, Nitrofurantoin, Macrobid, Macrodantin, Sulfasalazine, Azulfidine
Ear Nose Throat No underlying causes
Endocrine No underlying causes
Environmental Cigarette Smoke, Asbestos, silica, Coal dust, Beryllium, heavy metal dusts, Animal proteins, Bacteria, Molds, Radiation
Gastroenterologic Gastroesophageal reflux disease
Genetic No underlying causes
Hematologic No underlying causes
Iatrogenic No underlying causes
Infectious Disease Dermatomyositis, Polymyositis
Musculoskeletal / Ortho Rheumatoid arthritis
Neurologic No underlying causes
Nutritional / Metabolic No underlying causes
Obstetric/Gynecologic No underlying causes
Oncologic No underlying causes
Opthalmologic No underlying causes
Overdose / Toxicity No underlying causes
Psychiatric No underlying causes
Pulmonary Tuberculosis, Pneumonia, Anti-synthetase syndrome
Renal / Electrolyte No underlying causes
Rheum / Immune / Allergy Sarcoidosis, Systemic lupus erythematosus, Rheumatoid arthritis, Lupus pleuritis
Sexual No underlying causes
Trauma No underlying causes
Urologic No underlying causes
Dental No underlying causes
Miscellaneous No underlying causes

Causes in Alphabetical Order

References

  1. ↑ Olson AL, Swigris JJ (2012). "Idiopathic pulmonary fibrosis: diagnosis and epidemiology". Clin Chest Med. 33 (1): 41–50. doi:10.1016/j.ccm.2011.12.001. PMID 22365244.
  2. ↑ Williams KJ (2014). "Gammaherpesviruses and pulmonary fibrosis: evidence from humans, horses, and rodents". Vet Pathol. 51 (2): 372–84. doi:10.1177/0300985814521838. PMID 24569614.

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