Patent ductus arteriosus causes: Difference between revisions

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__NOTOC__
__NOTOC__
{{Patent ductus arteriosus}}
{{Patent ductus arteriosus}}
{{CMG}}; '''Associate Editor-In-Chief:''' [[Priyamvada Singh|Priyamvada Singh, M.B.B.S.]] [mailto:psingh13579@gmail.com], {{CZ}}, '''Assistant Editor-In-Chief:''' [[Kristin Feeney|Kristin Feeney, B.S.]] [mailto:kfeeney@elon.edu]
{{CMG}}; '''Associate Editor-In-Chief:''' [[Priyamvada Singh|Priyamvada Singh, M.B.B.S.]] [mailto:psingh13579@gmail.com], {{CZ}}, '''Assistant Editor-In-Chief:''' [[Kristin Feeney|Kristin Feeney, B.S.]] [mailto:kfeeney@elon.edu] {{RG}}
==Overview==
==Overview==
Causes of Patent ductus arteriosus is not known. However, increased [[incidence]] have been associated with mother's [[rubella]] and [[genetic]] causes
Causes of [[Patent ductus arteriosus]] is not known. However, increased [[incidence]] have been associated with mother's [[rubella]] and [[genetic]] causes


==Causes==
==Causes==
*Genetic factors - It has been found to occur with increased frequencies in some families, indicating some association with [[autosomal dominant]] inheritence <ref name="pmid8326495">{{cite journal| author=Davidson HR| title=A large family with patent ductus arteriosus and unusual face. | journal=J Med Genet | year= 1993 | volume= 30 | issue= 6 | pages= 503-5 | pmid=8326495 | doi= | pmc=PMC1016426 | url= }} </ref>. The exact gene location for patent ductus arteriosus has not yet been determined.  
===Common Causes===
*[[Congenital rubella]] (associated with PDA and [[pulmonary artery]] stenosis)
Common causes of [[patent ductus arteriosus]] may include:
*[[Fetal alcohol syndrome]]
*[[Genetics|Genetic]] factors<ref name="pmid8326495">{{cite journal| author=Davidson HR| title=A large family with patent ductus arteriosus and unusual face. | journal=J Med Genet | year= 1993 | volume= 30 | issue= 6 | pages= 503-5 | pmid=8326495 | doi= | pmc=PMC1016426 | url= }} </ref>
*Maternal [[drug]] use
**[[Patent ductus arteriosus|PDA]] has is highly familial. It is shown that with the effect of environmental elements.
**Studies shown the [[inheritance]] is more contributed to [[autosomal dominant]].<ref name="BhandariZhou2009">{{cite journal|last1=Bhandari|first1=V.|last2=Zhou|first2=G.|last3=Bizzarro|first3=M. J.|last4=Buhimschi|first4=C.|last5=Hussain|first5=N.|last6=Gruen|first6=J. R.|last7=Zhang|first7=H.|title=Genetic Contribution to Patent Ductus Arteriosus in the Premature Newborn|journal=PEDIATRICS|volume=123|issue=2|year=2009|pages=669–673|issn=0031-4005|doi=10.1542/peds.2008-1117}}</ref>
*[[Congenital rubella]]<ref name="Mekonnen2017">{{cite journal|last1=Mekonnen|first1=Demeke|title=Clinically confirmed congenital rubella syndrome: the role of echocardiography|journal=Ethiopian Journal of Health Sciences|volume=27|issue=2|year=2017|pages=197|issn=1029-1857|doi=10.4314/ejhs.v27i2.13}}</ref>
*[[Fetal alcohol syndrome]]<ref name="ArishimaYamamoto1993">{{cite journal|last1=Arishima|first1=Kazuyoshi|last2=Yamamoto|first2=Masako|last3=Takizawa|first3=Tatsuya|last4=Sohmiya|first4=Hiroaki|last5=Eguchi|first5=Yasunobu|last6=Shiota|first6=Kohei|title=Effect of Acute Maternal Alcohol Consumption on the Fetal Ductus arteriosus in the Rat|journal=Neonatology|volume=63|issue=1|year=1993|pages=40–43|issn=1661-7800|doi=10.1159/000243906}}</ref>
 
===Less Common Causes===
Less common causes of [[Patent ductus arteriosus|PDA]] include:
*Maternal [[teratogen]] drug use<ref name="ReeseVeldman2010">{{cite journal|last1=Reese|first1=Jeff|last2=Veldman|first2=Alex|last3=Shah|first3=Lisa|last4=Vucovich|first4=Megan|last5=Cotton|first5=Robert B.|title=Inadvertent Relaxation of the Ductus Arteriosus by Pharmacologic Agents that are Commonly Used in the Neonatal Period|journal=Seminars in Perinatology|volume=34|issue=3|year=2010|pages=222–230|issn=01460005|doi=10.1053/j.semperi.2010.02.007}}</ref>:
**[[Amphetamine]]
**[[Amphetamine]]
**[[Clomifene]]
**[[Phenytoin]]
**[[Phenytoin]]
===Causes by Organ System===
{|style="width:80%; height:100px" border="1"
|style="height:100px"; style="width:25%" border="1" bgcolor="LightSteelBlue" |'''Cardiovascular'''
|style="height:100px"; style="width:75%" border="1" bgcolor="Beige" | No underlying causes
|-
|bgcolor="LightSteelBlue"| '''Chemical/Poisoning'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Dental'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Dermatologic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Drug Side Effect'''
|bgcolor="Beige"| Maternal [[Amphetamine]], [[Clomifene]], [[Phenytoin]], [[Fetal alcohol spectrum disorder|Alcohol]] use
|-
|-bgcolor="LightSteelBlue"
| '''Ear Nose Throat'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Endocrine'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Environmental'''
|bgcolor="Beige"| Many underlying co founders in research
|-
|-bgcolor="LightSteelBlue"
| '''Gastroenterologic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Genetic'''
|bgcolor="Beige"|[[Autosomal dominant]] inheritance reported
|-
|-bgcolor="LightSteelBlue"
| '''Hematologic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Iatrogenic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Infectious Disease'''
|bgcolor="Beige"|[[Congenital rubella syndrome|Congenital rubella]] infection
|-
|-bgcolor="LightSteelBlue"
| '''Musculoskeletal/Orthopedic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Neurologic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Nutritional/Metabolic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Obstetric/Gynecologic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Oncologic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Ophthalmologic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Overdose/Toxicity'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Psychiatric'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Pulmonary'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Renal/Electrolyte'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Rheumatology/Immunology/Allergy'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Sexual'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Trauma'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Urologic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Miscellaneous'''
|bgcolor="Beige"| No underlying causes
|-
|}
<div style="-moz-column-count:3; column-count:3;">
*
</div>


==References==
==References==

Latest revision as of 22:45, 9 March 2020

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor-In-Chief: Priyamvada Singh, M.B.B.S. [2], Cafer Zorkun, M.D., Ph.D. [3], Assistant Editor-In-Chief: Kristin Feeney, B.S. [4] Ramyar Ghandriz MD[5]

Overview

Causes of Patent ductus arteriosus is not known. However, increased incidence have been associated with mother's rubella and genetic causes

Causes

Common Causes

Common causes of patent ductus arteriosus may include:

Less Common Causes

Less common causes of PDA include:

Causes by Organ System

Cardiovascular No underlying causes
Chemical/Poisoning No underlying causes
Dental No underlying causes
Dermatologic No underlying causes
Drug Side Effect Maternal Amphetamine, Clomifene, Phenytoin, Alcohol use
Ear Nose Throat No underlying causes
Endocrine No underlying causes
Environmental Many underlying co founders in research
Gastroenterologic No underlying causes
Genetic Autosomal dominant inheritance reported
Hematologic No underlying causes
Iatrogenic No underlying causes
Infectious Disease Congenital rubella infection
Musculoskeletal/Orthopedic No underlying causes
Neurologic No underlying causes
Nutritional/Metabolic No underlying causes
Obstetric/Gynecologic No underlying causes
Oncologic No underlying causes
Ophthalmologic No underlying causes
Overdose/Toxicity No underlying causes
Psychiatric No underlying causes
Pulmonary No underlying causes
Renal/Electrolyte No underlying causes
Rheumatology/Immunology/Allergy No underlying causes
Sexual No underlying causes
Trauma No underlying causes
Urologic No underlying causes
Miscellaneous No underlying causes

References

  1. Davidson HR (1993). "A large family with patent ductus arteriosus and unusual face". J Med Genet. 30 (6): 503–5. PMC 1016426. PMID 8326495.
  2. Bhandari, V.; Zhou, G.; Bizzarro, M. J.; Buhimschi, C.; Hussain, N.; Gruen, J. R.; Zhang, H. (2009). "Genetic Contribution to Patent Ductus Arteriosus in the Premature Newborn". PEDIATRICS. 123 (2): 669–673. doi:10.1542/peds.2008-1117. ISSN 0031-4005.
  3. Mekonnen, Demeke (2017). "Clinically confirmed congenital rubella syndrome: the role of echocardiography". Ethiopian Journal of Health Sciences. 27 (2): 197. doi:10.4314/ejhs.v27i2.13. ISSN 1029-1857.
  4. Arishima, Kazuyoshi; Yamamoto, Masako; Takizawa, Tatsuya; Sohmiya, Hiroaki; Eguchi, Yasunobu; Shiota, Kohei (1993). "Effect of Acute Maternal Alcohol Consumption on the Fetal Ductus arteriosus in the Rat". Neonatology. 63 (1): 40–43. doi:10.1159/000243906. ISSN 1661-7800.
  5. Reese, Jeff; Veldman, Alex; Shah, Lisa; Vucovich, Megan; Cotton, Robert B. (2010). "Inadvertent Relaxation of the Ductus Arteriosus by Pharmacologic Agents that are Commonly Used in the Neonatal Period". Seminars in Perinatology. 34 (3): 222–230. doi:10.1053/j.semperi.2010.02.007. ISSN 0146-0005.

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