Heart transplantation epidemiology and demographics: Difference between revisions

Jump to navigation Jump to search
VisualWikitext
No edit summary
 
(13 intermediate revisions by the same user not shown)
Line 2: Line 2:
{{Heart transplantation}}
{{Heart transplantation}}


'''Editor(s)-in-Chief:''' [[C. Michael  Gibson, M.S., M.D.]]; '''Associate Editor-In-Chief:''' {{CZ}}
'''Editor(s)-in-Chief:''' [[C. Michael  Gibson, M.S., M.D.]]; '''Associate Editor-In-Chief:''' {{CZ}}{{IF}}
==Overview==
==Overview==
About 4,000 [[Heart transplantation|heart transplant]]<nowiki/>s occur annually and about 2,200 per year in the [[United States]]. The leading [[Indication (medicine)|indications]] for transplant in [[adult]] recipients is
non-ischemic [[dilated cardiomyopathy]]. The median recipient age is 55 years. Death due to acute [[Transplant rejection|graft rejection]] is highest in the first 30 days and [[Infection|infectious]] [[complications]] are the leading cause in the first year. Post-transplant [[Survival analysis|survival]] has improved over time.


==Epidemiology and Demographics==
==Epidemiology and Demographics==
Reporting of transplant statistics to the Registry of the International Society for Heart and Lung Transplantation (ISHLT) is required in the US, but not other countries. According to The International Thoracic Organ Transplant Registry of the International Society for Heart and Lung Transplantation: Thirty-sixth adult heart transplantation report — 2019: <ref name="pmid31548031">{{cite journal| author=Khush KK, Cherikh WS, Chambers DC, Harhay MO, Hayes D, Hsich E | display-authors=etal| title=The International Thoracic Organ Transplant Registry of the International Society for Heart and Lung Transplantation: Thirty-sixth adult heart transplantation report - 2019; focus theme: Donor and recipient size match. | journal=J Heart Lung Transplant | year= 2019 | volume= 38 | issue= 10 | pages= 1056-1066 | pmid=31548031 | doi=10.1016/j.healun.2019.08.004 | pmc=6816343 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=31548031  }} </ref> <ref> https://ishlt.org/ </ref>
===Incidence===
===Incidence===
*The incidence/prevalence of [disease name] is approximately [number range] per 100,000 individuals worldwide.
* The incidence of heart transplants is approximately 4,000 heart transplants worldwide and about 2,200 per year in the United States, according to the [https://ishlt.org/ ISHLT]
*In [year], the incidence/prevalence of [disease name] was estimated to be [number range] cases per 100,000 individuals worldwide.
* The volume of heart [[Organ transplant|transplants]] reported to the [https://ishlt.org/ ISHLT] Registry is significantly higher owing to higher donor availability.
* In the year 1980s-1990s, the incidence of heart transplants saw a steady increase, but numbers have since stabilized because of the limited number of donors.


===Prevalence===
===Prevalence===
*The incidence/prevalence of [disease name] is approximately [number range] per 100,000 individuals worldwide.
*The prevalence of heart transplants is approximately 4,000 heart transplants worldwide and about 2,200 per year in the United States, according to the [https://ishlt.org/ ISHLT]
*In [year], the incidence/prevalence of [disease name] was estimated to be [number range] cases per 100,000 individuals worldwide.
*The prevalence of [disease/malignancy] is estimated to be [number] cases annually.


===Case-fatality rate/Mortality rate===
===Case-fatality rate/Mortality rate===
*In [year], the incidence of [disease name] is approximately [number range] per 100,000 individuals with a case-fatality rate/mortality rate of [number range]%.
* The survival rate of post-transplant patients was approximately 12.5 years, between 2002 and 2009. <ref name="pmid31548031">{{cite journal| author=Khush KK, Cherikh WS, Chambers DC, Harhay MO, Hayes D, Hsich E | display-authors=etal| title=The International Thoracic Organ Transplant Registry of the International Society for Heart and Lung Transplantation: Thirty-sixth adult heart transplantation report - 2019; focus theme: Donor and recipient size match. | journal=J Heart Lung Transplant | year= 2019 | volume= 38 | issue= 10 | pages= 1056-1066 | pmid=31548031 | doi=10.1016/j.healun.2019.08.004 | pmc=6816343 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=31548031  }} </ref>
*The case-fatality rate/mortality rate of [disease name] is approximately [number range].
* The 1-year survival is 84.5% and 5-year survival is 72.5%. <ref name="pmid25242124">{{cite journal| author=Lund LH, Edwards LB, Kucheryavaya AY, Benden C, Christie JD, Dipchand AI | display-authors=etal| title=The registry of the International Society for Heart and Lung Transplantation: thirty-first official adult heart transplant report--2014; focus theme: retransplantation. | journal=J Heart Lung Transplant | year= 2014 | volume= 33 | issue= 10 | pages= 996-1008 | pmid=25242124 | doi=10.1016/j.healun.2014.08.003 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25242124  }} </ref>
* Post-transplant [[Survival analysis|survival]] has improved over time.
* Causes of death in the long term have not changed in recent years. Death due to [[Graft rejection|acute graft rejection]] is highest in the first 30 days and [[Infection|infectious]] [[Complication (medicine)|complications]] are the leading cause in the first year.


===Age===
===Age===
*Patients of all age groups may develop [disease name].
* The incidence of cardiac transplantation increases with age; median recipient age is 55 years.  
*The incidence of [disease name] increases with age; the median age at diagnosis is [#] years.
* Median [[donor]] age in Europe has increased to 45 years and remains relatively stable in North America at 28 years and other countries at 31 years.
*[Disease name] commonly affects individuals younger than/older than [number of years] years of age.  
*[Chronic disease name] is usually first diagnosed among [age group].
*[Acute disease name] commonly affects [age group].


===Race===
===Race===
*There is no racial predilection to [disease name].
*There is no racial predilection to [[cardiac transplantation]].  
*[Disease name] usually affects individuals of the [race 1] race. [Race 2] individuals are less likely to develop [disease name].
 
===Gender===
===Gender===
*[Disease name] affects men and women equally.
* [[Male|males]] undergo [[Heart transplantation|cardiac transplant]] more commonly than women, according to the data from the [https://ishlt.org/ ISHLT] between 2009-2016. <ref name="pmid29968430">{{cite journal| author=Kim IC, Youn JC, Kobashigawa JA| title=The Past, Present and Future of Heart Transplantation. | journal=Korean Circ J | year= 2018 | volume= 48 | issue= 7 | pages= 565-590 | pmid=29968430 | doi=10.4070/kcj.2018.0189 | pmc=6031715 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29968430  }} </ref>
*[Gender 1] are more commonly affected by [disease name] than [gender 2]. The [gender 1] to [gender 2] ratio is approximately [number > 1] to 1.


===Region===
===Region===
*The majority of [disease name] cases are reported in [geographical region].
* The majority of heart transplant cases are reported in the United States.
 
* The [https://ishlt.org/ International Society for Heart and Lung Transplantation (ISHLT)] compiles the data of cardiac transplants and other involved statistics in the United States.
*[Disease name] is a common/rare disease that tends to affect [patient population 1] and [patient population 2].
* Reporting of transplant statistics to the Registry of the [https://ishlt.org/ International Society for Heart and Lung Transplantation (ISHLT)] is required in the US, but not other countries.


===Developed Countries===
===Developed Countries===
* Reporting of transplant statistics to the Registry of the [https://ishlt.org/ International Society for Heart and Lung Transplantation (ISHLT)] is required in the US, but not other countries. <ref name="pmid31548031">{{cite journal| author=Khush KK, Cherikh WS, Chambers DC, Harhay MO, Hayes D, Hsich E | display-authors=etal| title=The International Thoracic Organ Transplant Registry of the International Society for Heart and Lung Transplantation: Thirty-sixth adult heart transplantation report - 2019; focus theme: Donor and recipient size match. | journal=J Heart Lung Transplant | year= 2019 | volume= 38 | issue= 10 | pages= 1056-1066 | pmid=31548031 | doi=10.1016/j.healun.2019.08.004 | pmc=6816343 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=31548031  }} </ref>


===Developing Countries===
===Developing Countries===
 
* Reporting of transplant statistics to the Registry of the [https://ishlt.org/ International Society for Heart and Lung Transplantation (ISHLT)] is required in the US, but not other countries. <ref name="pmid31548031">{{cite journal| author=Khush KK, Cherikh WS, Chambers DC, Harhay MO, Hayes D, Hsich E | display-authors=etal| title=The International Thoracic Organ Transplant Registry of the International Society for Heart and Lung Transplantation: Thirty-sixth adult heart transplantation report - 2019; focus theme: Donor and recipient size match. | journal=J Heart Lung Transplant | year= 2019 | volume= 38 | issue= 10 | pages= 1056-1066 | pmid=31548031 | doi=10.1016/j.healun.2019.08.004 | pmc=6816343 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=31548031  }} </ref>
==Epidemiology and Demographics==
Reporting of transplant statistics to the Registry of the International Society for Heart and Lung Transplantation (ISHLT) is required in the US, but not other countries. According to The International Thoracic Organ Transplant Registry of the International Society for Heart and Lung Transplantation: Thirty-sixth adult heart transplantation report — 2019: <ref name="pmid31548031">{{cite journal| author=Khush KK, Cherikh WS, Chambers DC, Harhay MO, Hayes D, Hsich E | display-authors=etal| title=The International Thoracic Organ Transplant Registry of the International Society for Heart and Lung Transplantation: Thirty-sixth adult heart transplantation report - 2019; focus theme: Donor and recipient size match. | journal=J Heart Lung Transplant | year= 2019 | volume= 38 | issue= 10 | pages= 1056-1066 | pmid=31548031 | doi=10.1016/j.healun.2019.08.004 | pmc=6816343 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=31548031  }} </ref>
 
* The volume of heart transplants reported to the ISHLT Registry is significantly higher owing to increased donor availability.
* Median recipient age is 55 years
* Median donor age in Europe has increased to 45 years and remains relatively stable in North America at 28 years and other countries at 31 years.
* The leading indications for transplant in adult recipients are
**non-ischemic [[dilated cardiomyopathy]]- 51%
**[[ischemic cardiomyopathy]] 32%
* Post transplant survival has improved and the median survival after adult heart transplants performed between 2002 and 2009 is 12.5 years.
* Causes of death in the long term have not changed in recent years. Death due to acute graft rejection is highest in the first 30 days and infectious complications is leading cause in the first year.


==References==
==References==

Latest revision as of 17:50, 21 July 2020

Heart transplantation Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Epidemiology and Demographics

Risk Factors

Screening

Complications and Prognosis

Diagnosis

Indications

Evaluation

Contraindications

Criteria for Cardiac Transplantation

Equitable Distribution of Donor Hearts to those Awaiting Transplantation and the Process of Being Listed for a Transplant

Treatment

Medical Therapy

Surgery

Follow-Up

Electrocardiogram and Pacing After Cardiac Transplantation

Heart transplantation epidemiology and demographics On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Heart transplantation epidemiology and demographics

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Heart transplantation epidemiology and demographics

CDC onHeart transplantation epidemiology and demographics

Heart transplantation epidemiology and demographics in the news

Blogs on Heart transplantation epidemiology and demographics

Directions to Hospitals Treating Heart transplantation

Risk calculators and risk factors for Heart transplantation epidemiology and demographics

Editor(s)-in-Chief: C. Michael Gibson, M.S., M.D.; Associate Editor-In-Chief: Cafer Zorkun, M.D., Ph.D. [1]Ifrah Fatima, M.B.B.S[2]

Overview

About 4,000 heart transplants occur annually and about 2,200 per year in the United States. The leading indications for transplant in adult recipients is non-ischemic dilated cardiomyopathy. The median recipient age is 55 years. Death due to acute graft rejection is highest in the first 30 days and infectious complications are the leading cause in the first year. Post-transplant survival has improved over time.

Epidemiology and Demographics

Reporting of transplant statistics to the Registry of the International Society for Heart and Lung Transplantation (ISHLT) is required in the US, but not other countries. According to The International Thoracic Organ Transplant Registry of the International Society for Heart and Lung Transplantation: Thirty-sixth adult heart transplantation report — 2019: [1] [2]

Incidence

  • The incidence of heart transplants is approximately 4,000 heart transplants worldwide and about 2,200 per year in the United States, according to the ISHLT
  • The volume of heart transplants reported to the ISHLT Registry is significantly higher owing to higher donor availability.
  • In the year 1980s-1990s, the incidence of heart transplants saw a steady increase, but numbers have since stabilized because of the limited number of donors.

Prevalence

  • The prevalence of heart transplants is approximately 4,000 heart transplants worldwide and about 2,200 per year in the United States, according to the ISHLT

Case-fatality rate/Mortality rate

  • The survival rate of post-transplant patients was approximately 12.5 years, between 2002 and 2009. [1]
  • The 1-year survival is 84.5% and 5-year survival is 72.5%. [3]
  • Post-transplant survival has improved over time.
  • Causes of death in the long term have not changed in recent years. Death due to acute graft rejection is highest in the first 30 days and infectious complications are the leading cause in the first year.

Age

  • The incidence of cardiac transplantation increases with age; median recipient age is 55 years.
  • Median donor age in Europe has increased to 45 years and remains relatively stable in North America at 28 years and other countries at 31 years.

Race

Gender

Region

Developed Countries

Developing Countries

References

  1. ↑ 1.0 1.1 1.2 1.3 Khush KK, Cherikh WS, Chambers DC, Harhay MO, Hayes D, Hsich E; et al. (2019). "The International Thoracic Organ Transplant Registry of the International Society for Heart and Lung Transplantation: Thirty-sixth adult heart transplantation report - 2019; focus theme: Donor and recipient size match". J Heart Lung Transplant. 38 (10): 1056–1066. doi:10.1016/j.healun.2019.08.004. PMC 6816343 Check |pmc= value (help). PMID 31548031.
  2. ↑ https://ishlt.org/
  3. ↑ Lund LH, Edwards LB, Kucheryavaya AY, Benden C, Christie JD, Dipchand AI; et al. (2014). "The registry of the International Society for Heart and Lung Transplantation: thirty-first official adult heart transplant report--2014; focus theme: retransplantation". J Heart Lung Transplant. 33 (10): 996–1008. doi:10.1016/j.healun.2014.08.003. PMID 25242124.
  4. ↑ Kim IC, Youn JC, Kobashigawa JA (2018). "The Past, Present and Future of Heart Transplantation". Korean Circ J. 48 (7): 565–590. doi:10.4070/kcj.2018.0189. PMC 6031715. PMID 29968430.


Template:WikiDoc Sources

Retrieved from "https://www.wikidoc.org/index.php?title=Heart_transplantation_epidemiology_and_demographics&oldid=1630493"