Amoebic liver abscess history and symptoms: Difference between revisions
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==Overview== | ==Overview== | ||
Specific areas of focus when obtaining a history from the patient include history of recent travel to or resident of [[endemic|endemic areas]], time of onset (duration of symptoms <14 days), history of [[dysentery]] within the previous few months, [[fever]] and [[abdominal pain]].<ref name="pmid14557296">{{cite journal| author=Tanyuksel M, Petri WA| title=Laboratory diagnosis of amebiasis. | journal=Clin Microbiol Rev | year= 2003 | volume= 16 | issue= 4 | pages= 713-29 | pmid=14557296 | doi= | pmc=207118 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=14557296 }} </ref>[[Symptom]]s of amoebic liver abscess include moderate to severe [[abdominal pain]], [[malaise]], [[Appetite loss|loss of appetite]], sweating, [[weight loss]], [[epigastric pain]] (Commonly seen in [[Left lobe of liver|left lobe]] [[abscess|abscesses]]), [[fever]] (high [[fever]] with [[chills]] is suggestive of [[Bacterial infection|secondary bacterial infection]]), [[anorexia]], [[pleuritic chest pain]], [[Cough]] with or without expectoration and [[chest pain]] (may be due to [[abscess]] rupture into the [[pleural cavity]]), [[jaundice]], [[confusion]], [[abdominal distension]], [[nausea]] and [[vomiting]], [[diarrhea]] and [[constipation]]<ref name="pmid2219891">{{cite journal| author=Lyche KD, Jensen WA, Kirsch CM, Yenokida GG, Maltz GS, Knauer CM| title=Pleuropulmonary manifestations of hepatic amebiasis. | journal=West J Med | year= 1990 | volume= 153 | issue= 3 | pages= 275-8 | pmid=2219891 | doi= | pmc=1002529 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=2219891 }} </ref><ref name="pmid21731305">{{cite journal| author=Ximénez C, Morán P, Rojas L, Valadez A, Gómez A, Ramiro M et al.| title=Novelties on amoebiasis: a neglected tropical disease. | journal=J Glob Infect Dis | year= 2011 | volume= 3 | issue= 2 | pages= 166-74 | pmid=21731305 | doi=10.4103/0974-777X.81695 | pmc=3125031 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21731305 }} </ref><ref name="pmid19540361">{{cite journal| author=Ximénez C, Morán P, Rojas L, Valadez A, Gómez A| title=Reassessment of the epidemiology of amebiasis: state of the art. | journal=Infect Genet Evol | year= 2009 | volume= 9 | issue= 6 | pages= 1023-32 | pmid=19540361 | doi=10.1016/j.meegid.2009.06.008 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19540361 }} </ref><ref name="pmid18828976">{{cite journal| author=Pritt BS, Clark CG| title=Amebiasis. | journal=Mayo Clin Proc | year= 2008 | volume= 83 | issue= 10 | pages= 1154-9; quiz 1159-60 | pmid=18828976 | doi=10.4065/83.10.1154 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18828976 }} </ref><ref name="pmid18398490">{{cite journal| author=Ali IK, Solaymani-Mohammadi S, Akhter J, Roy S, Gorrini C, Calderaro A et al.| title=Tissue invasion by Entamoeba histolytica: evidence of genetic selection and/or DNA reorganization events in organ tropism. | journal=PLoS Negl Trop Dis | year= 2008 | volume= 2 | issue= 4 | pages= e219 | pmid=18398490 | doi=10.1371/journal.pntd.0000219 | pmc=2274956 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18398490 }} </ref><ref name="pmid20617021">{{cite journal| author=Ximénez C, Cerritos R, Rojas L, Dolabella S, Morán P, Shibayama M et al.| title=Human amebiasis: breaking the paradigm? | journal=Int J Environ Res Public Health | year= 2010 | volume= 7 | issue= 3 | pages= 1105-20 | pmid=20617021 | doi=10.3390/ijerph7031105 | pmc=2872301 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20617021 }} </ref> | |||
==History== | ==History== | ||
Specific areas of focus when obtaining a history from the patient include history of amoebic liver abscess include:<ref name="pmid14557296">{{cite journal| author=Tanyuksel M, Petri WA| title=Laboratory diagnosis of amebiasis. | journal=Clin Microbiol Rev | year= 2003 | volume= 16 | issue= 4 | pages= 713-29 | pmid=14557296 | doi= | pmc=207118 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=14557296 }} </ref> | |||
*History of recent travel to or resident of [[endemic|endemic areas]] | |||
*Time of onset (duration of symptoms <14 days) | *Time of onset (duration of symptoms <14 days) | ||
*History of dysentery within the previous few months | *History of [[dysentery]] within the previous few months | ||
*History of fever and abdominal pain | *History of [[fever]] and [[abdominal pain]] | ||
==Symptoms== | ==Symptoms== | ||
After exposure, 80% of infected patients develop symptoms with in few days to 4-5 weeks. Symptoms of amoebic liver abscess include:<ref name="pmid21731305">{{cite journal| author=Ximénez C, Morán P, Rojas L, Valadez A, Gómez A, Ramiro M et al.| title=Novelties on amoebiasis: a neglected tropical disease. | journal=J Glob Infect Dis | year= 2011 | volume= 3 | issue= 2 | pages= 166-74 | pmid=21731305 | doi=10.4103/0974-777X.81695 | pmc=3125031 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21731305 }} </ref><ref name="pmid19540361">{{cite journal| author=Ximénez C, Morán P, Rojas L, Valadez A, Gómez A| title=Reassessment of the epidemiology of amebiasis: state of the art. | journal=Infect Genet Evol | year= 2009 | volume= 9 | issue= 6 | pages= 1023-32 | pmid=19540361 | doi=10.1016/j.meegid.2009.06.008 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19540361 }} </ref><ref name="pmid18828976">{{cite journal| author=Pritt BS, Clark CG| title=Amebiasis. | journal=Mayo Clin Proc | year= 2008 | volume= 83 | issue= 10 | pages= 1154-9; quiz 1159-60 | pmid=18828976 | doi=10.4065/83.10.1154 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18828976 }} </ref><ref name="pmid18398490">{{cite journal| author=Ali IK, Solaymani-Mohammadi S, Akhter J, Roy S, Gorrini C, Calderaro A et al.| title=Tissue invasion by Entamoeba histolytica: evidence of genetic selection and/or DNA reorganization events in organ tropism. | journal=PLoS Negl Trop Dis | year= 2008 | volume= 2 | issue= 4 | pages= e219 | pmid=18398490 | doi=10.1371/journal.pntd.0000219 | pmc=2274956 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18398490 }} </ref><ref name="pmid20617021">{{cite journal| author=Ximénez C, Cerritos R, Rojas L, Dolabella S, Morán P, Shibayama M et al.| title=Human amebiasis: breaking the paradigm? | journal=Int J Environ Res Public Health | year= 2010 | volume= 7 | issue= 3 | pages= 1105-20 | pmid=20617021 | doi=10.3390/ijerph7031105 | pmc=2872301 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20617021 }} </ref> | After exposure, 80% of [[infected|infection]] patients develop symptoms with in few days to 4-5 weeks. Symptoms of [[amoebic liver abscess]] include:<ref name="pmid21731305">{{cite journal| author=Ximénez C, Morán P, Rojas L, Valadez A, Gómez A, Ramiro M et al.| title=Novelties on amoebiasis: a neglected tropical disease. | journal=J Glob Infect Dis | year= 2011 | volume= 3 | issue= 2 | pages= 166-74 | pmid=21731305 | doi=10.4103/0974-777X.81695 | pmc=3125031 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21731305 }} </ref><ref name="pmid19540361">{{cite journal| author=Ximénez C, Morán P, Rojas L, Valadez A, Gómez A| title=Reassessment of the epidemiology of amebiasis: state of the art. | journal=Infect Genet Evol | year= 2009 | volume= 9 | issue= 6 | pages= 1023-32 | pmid=19540361 | doi=10.1016/j.meegid.2009.06.008 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19540361 }} </ref><ref name="pmid18828976">{{cite journal| author=Pritt BS, Clark CG| title=Amebiasis. | journal=Mayo Clin Proc | year= 2008 | volume= 83 | issue= 10 | pages= 1154-9; quiz 1159-60 | pmid=18828976 | doi=10.4065/83.10.1154 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18828976 }} </ref><ref name="pmid18398490">{{cite journal| author=Ali IK, Solaymani-Mohammadi S, Akhter J, Roy S, Gorrini C, Calderaro A et al.| title=Tissue invasion by Entamoeba histolytica: evidence of genetic selection and/or DNA reorganization events in organ tropism. | journal=PLoS Negl Trop Dis | year= 2008 | volume= 2 | issue= 4 | pages= e219 | pmid=18398490 | doi=10.1371/journal.pntd.0000219 | pmc=2274956 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18398490 }} </ref><ref name="pmid20617021">{{cite journal| author=Ximénez C, Cerritos R, Rojas L, Dolabella S, Morán P, Shibayama M et al.| title=Human amebiasis: breaking the paradigm? | journal=Int J Environ Res Public Health | year= 2010 | volume= 7 | issue= 3 | pages= 1105-20 | pmid=20617021 | doi=10.3390/ijerph7031105 | pmc=2872301 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20617021 }} </ref> | ||
*Moderate to severe abdominal pain | |||
:* | '''Common symptoms''' | ||
:* | *Moderate to severe [[abdominal pain]] | ||
:*Pain aggravates with coughing, deep breathing, walking and while resting on right side | :*Localized to [[right upper quadrant]] radiated to right shoulder or diffuse | ||
*Malaise (uneasiness, or ill feeling) | :*Pain is intense, continuous or stabbing | ||
*Loss of appetite | :*Pain aggravates with [[cough|coughing]], deep breathing, walking and while resting on right side | ||
*Sweating | *[[Malaise]] (uneasiness, or ill feeling) | ||
*Weight loss | *[[Loss of appetite]] | ||
*Epigastric pain (Commonly seen in left lobe abscesses) | *[[Nausea]] and [[vomiting]] | ||
*Fever (high fever with chills is suggestive of secondary bacterial infection) | *[[Sweating]] | ||
*Anorexia | *[[Weight loss]] | ||
*Pleuritic chest pain | *[[Epigastric]] pain (Commonly seen in left lobe [[abscess|abscesses]]) | ||
*Cough with or without expectoration and chest pain (may be due to abscess rupture into the pleural cavity) | *[[Fever]] (high [[fever]] with chills is suggestive of secondary [[bacterial infection]]) | ||
:*Cough with odorless brown sputum indicates hepatopulmonary fistula<ref name="pmid2219891">{{cite journal| author=Lyche KD, Jensen WA, Kirsch CM, Yenokida GG, Maltz GS, Knauer CM| title=Pleuropulmonary manifestations of hepatic amebiasis. | journal=West J Med | year= 1990 | volume= 153 | issue= 3 | pages= 275-8 | pmid=2219891 | doi= | pmc=1002529 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=2219891 }} </ref> | *[[Anorexia]] | ||
*Yellow discoloration of skin (Jaundice is seen in 1/3 of patients) | *[[Constipation]] | ||
*Confusion (due to encephalopathy) | |||
*Abdominal distension (due to ascites) | '''Symptoms associated with complications''' | ||
* | *[[Pleuritic chest pain]] | ||
*[[Cough]] with or without expectoration and [[chest pain]] (may be due to [[abscess]] rupture into the [[pleural cavity]]) | |||
:*[[Cough]] with odorless brown sputum indicates hepatopulmonary [[fistula]]<ref name="pmid2219891">{{cite journal| author=Lyche KD, Jensen WA, Kirsch CM, Yenokida GG, Maltz GS, Knauer CM| title=Pleuropulmonary manifestations of hepatic amebiasis. | journal=West J Med | year= 1990 | volume= 153 | issue= 3 | pages= 275-8 | pmid=2219891 | doi= | pmc=1002529 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=2219891 }} </ref> | |||
*Yellow discoloration of skin ([[Jaundice]] is seen in 1/3 of patients) | |||
*[[Confusion]] (due to [[encephalopathy]]) | |||
*[[Abdominal distension]] (due to [[ascites]]) | |||
*[[Diarrhea]] | |||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
[[Category:Disease]] | |||
[[Category:Up-To-Date]] | |||
[[Category:Gastroenterology]] | |||
[[Category:Surgery]] | |||
[[Category:Emergency medicine]] | |||
[[Category:Infectious disease]] | |||
[[Category:Hepatology]] | |||
Latest revision as of 20:23, 29 July 2020
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Amoebic liver abscess history and symptoms On the Web |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Yamuna Kondapally, M.B.B.S[2]
Overview
Specific areas of focus when obtaining a history from the patient include history of recent travel to or resident of endemic areas, time of onset (duration of symptoms <14 days), history of dysentery within the previous few months, fever and abdominal pain.[1]Symptoms of amoebic liver abscess include moderate to severe abdominal pain, malaise, loss of appetite, sweating, weight loss, epigastric pain (Commonly seen in left lobe abscesses), fever (high fever with chills is suggestive of secondary bacterial infection), anorexia, pleuritic chest pain, Cough with or without expectoration and chest pain (may be due to abscess rupture into the pleural cavity), jaundice, confusion, abdominal distension, nausea and vomiting, diarrhea and constipation[2][3][4][5][6][7]
History
Specific areas of focus when obtaining a history from the patient include history of amoebic liver abscess include:[1]
- History of recent travel to or resident of endemic areas
- Time of onset (duration of symptoms <14 days)
- History of dysentery within the previous few months
- History of fever and abdominal pain
Symptoms
After exposure, 80% of infection patients develop symptoms with in few days to 4-5 weeks. Symptoms of amoebic liver abscess include:[3][4][5][6][7]
Common symptoms
- Moderate to severe abdominal pain
- Localized to right upper quadrant radiated to right shoulder or diffuse
- Pain is intense, continuous or stabbing
- Pain aggravates with coughing, deep breathing, walking and while resting on right side
- Malaise (uneasiness, or ill feeling)
- Loss of appetite
- Nausea and vomiting
- Sweating
- Weight loss
- Epigastric pain (Commonly seen in left lobe abscesses)
- Fever (high fever with chills is suggestive of secondary bacterial infection)
- Anorexia
- Constipation
Symptoms associated with complications
- Pleuritic chest pain
- Cough with or without expectoration and chest pain (may be due to abscess rupture into the pleural cavity)
- Yellow discoloration of skin (Jaundice is seen in 1/3 of patients)
- Confusion (due to encephalopathy)
- Abdominal distension (due to ascites)
- Diarrhea
References
- ↑ 1.0 1.1 Tanyuksel M, Petri WA (2003). "Laboratory diagnosis of amebiasis". Clin Microbiol Rev. 16 (4): 713–29. PMC 207118. PMID 14557296.
- ↑ 2.0 2.1 Lyche KD, Jensen WA, Kirsch CM, Yenokida GG, Maltz GS, Knauer CM (1990). "Pleuropulmonary manifestations of hepatic amebiasis". West J Med. 153 (3): 275–8. PMC 1002529. PMID 2219891.
- ↑ 3.0 3.1 Ximénez C, Morán P, Rojas L, Valadez A, Gómez A, Ramiro M; et al. (2011). "Novelties on amoebiasis: a neglected tropical disease". J Glob Infect Dis. 3 (2): 166–74. doi:10.4103/0974-777X.81695. PMC 3125031. PMID 21731305.
- ↑ 4.0 4.1 Ximénez C, Morán P, Rojas L, Valadez A, Gómez A (2009). "Reassessment of the epidemiology of amebiasis: state of the art". Infect Genet Evol. 9 (6): 1023–32. doi:10.1016/j.meegid.2009.06.008. PMID 19540361.
- ↑ 5.0 5.1 Pritt BS, Clark CG (2008). "Amebiasis". Mayo Clin Proc. 83 (10): 1154–9, quiz 1159-60. doi:10.4065/83.10.1154. PMID 18828976.
- ↑ 6.0 6.1 Ali IK, Solaymani-Mohammadi S, Akhter J, Roy S, Gorrini C, Calderaro A; et al. (2008). "Tissue invasion by Entamoeba histolytica: evidence of genetic selection and/or DNA reorganization events in organ tropism". PLoS Negl Trop Dis. 2 (4): e219. doi:10.1371/journal.pntd.0000219. PMC 2274956. PMID 18398490.
- ↑ 7.0 7.1 Ximénez C, Cerritos R, Rojas L, Dolabella S, Morán P, Shibayama M; et al. (2010). "Human amebiasis: breaking the paradigm?". Int J Environ Res Public Health. 7 (3): 1105–20. doi:10.3390/ijerph7031105. PMC 2872301. PMID 20617021.