Blindness causes: Difference between revisions
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__NOTOC__ | __NOTOC__ | ||
{{Blindness}} | {{Blindness}} | ||
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{{CMG}} {{AE}} {{SME}} | {{CMG}} {{AE}} {{SME}} | ||
==Common Causes== | ==Causes== | ||
===Common Causes=== | |||
Serious visual impairment has a variety of causes: | Serious visual impairment has a variety of causes: | ||
===Diseases=== | ====Diseases==== | ||
Most visual impairment is caused by [[disease]] and [[malnutrition]]. According to [[World Health Organization|WHO]] estimates in 2002, the most common causes of blindness around the world are: | Most visual impairment is caused by [[disease]] and [[malnutrition]]. According to [[World Health Organization|WHO]] estimates in 2002, the most common causes of blindness around the world are: | ||
*[[cataracts]] (47.8%), | *[[cataracts]] (47.8%), | ||
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*[[cornea]]l opacity (5.1%), and | *[[cornea]]l opacity (5.1%), and | ||
*[[diabetic retinopathy]] (4.8%), among other causes. | *[[diabetic retinopathy]] (4.8%), among other causes. | ||
*[[Medications]]- [[Dexamethasone]] | |||
People in developing countries are significantly more likely to experience visual impairment as a consequence of treatable or preventable conditions than are their counterparts in the developed world. While vision impairment is most common in people over age 60 across all regions, children in poorer communities are more likely to be affected by blinding diseases than are their more affluent peers. | People in developing countries are significantly more likely to experience visual impairment as a consequence of treatable or preventable conditions than are their counterparts in the developed world. While vision impairment is most common in people over age 60 across all regions, children in poorer communities are more likely to be affected by blinding diseases than are their more affluent peers. | ||
The link between | The link between poverty and treatable visual impairment is most obvious when conducting regional comparisons of cause. Most adult visual impairment in North America and Western Europe is related to age-related [[macular degeneration]] and [[diabetic retinopathy]]. While both of these conditions are subject to treatment, neither can be cured. Another common cause is [[retinopathy of prematurity]]. | ||
In developing countries, wherein people have shorter life expectancies, cataracts and water-borne parasites—both of which can be treated effectively—are most often the culprits (see [[Onchocerciasis|River blindness]], for example). Of the estimated 40 million blind people located around the world, 70–80% can have some or all of their sight restored through treatment. | In developing countries, wherein people have shorter life expectancies, [[cataracts]] and water-borne [[parasites]]—both of which can be treated effectively—are most often the culprits (see [[Onchocerciasis|River blindness]], for example). Of the estimated 40 million blind people located around the world, 70–80% can have some or all of their sight restored through treatment. | ||
In developed countries where parasitic diseases are less common and [[cataract surgery]] is more available, age-related macular degeneration, glaucoma, and diabetic retinopathy are usually the leading causes of blindness<ref name="Bunce">Bunce C, Wormald R. [http://www.pubmedcentral.gov/articlerender.fcgi?tool=pubmed&pubmedid=16524463 "Leading Causes of Certification for Blindness and Partial Sight in England & Wales."] ''BMC Public Health.'' 2006 Mar 8;6(1):58 [Epub ahead of print]. PMID 16524463.</ref>. | In developed countries where parasitic diseases are less common and [[cataract surgery]] is more available, age-related macular degeneration, glaucoma, and diabetic retinopathy are usually the leading causes of blindness<ref name="Bunce">Bunce C, Wormald R. [http://www.pubmedcentral.gov/articlerender.fcgi?tool=pubmed&pubmedid=16524463 "Leading Causes of Certification for Blindness and Partial Sight in England & Wales."] ''BMC Public Health.'' 2006 Mar 8;6(1):58 [Epub ahead of print]. PMID 16524463.</ref>. | ||
===Abnormalities and | ====Abnormalities and Injuries==== | ||
Eye injuries, most often occurring in people under 30, are the leading cause of monocular blindness (vision loss in one eye) throughout the [[United States]]. Injuries and cataracts affect the eye itself, while abnormalities such as [[optic nerve hypoplasia]] affect the nerve bundle that sends signals from the eye to the back of the brain, which can lead to decreased visual acuity. | Eye injuries, most often occurring in people under 30, are the leading cause of [[monocular blindness]] (vision loss in one eye) throughout the [[United States]]. Injuries and cataracts affect the eye itself, while abnormalities such as [[optic nerve hypoplasia]] affect the [[nerve]] bundle that sends signals from the eye to the back of the brain, which can lead to decreased [[visual acuity]]. | ||
People with injuries to the [[occipital lobe]] of the [[brain]] can, despite having undamaged eyes and [[optic nerve]]s, still be legally or totally blind. | People with injuries to the [[occipital lobe]] of the [[brain]] can, despite having undamaged eyes and [[optic nerve]]s, still be legally or totally blind. | ||
===Genetic | ====Genetic Defects==== | ||
People with [[albinism]] often suffer from visual impairment to the extent that many are legally blind, though few of them actually cannot see. [[Leber's congenital amaurosis]] can cause total blindness or severe sight loss from birth or early childhood. | People with [[albinism]] often suffer from visual impairment to the extent that many are legally blind, though few of them actually cannot see. [[Leber's congenital amaurosis]] can cause total blindness or severe sight loss from birth or early childhood. | ||
Recent advances in [[genetic map|mapping]] the [[human genome]] have identified other genetic causes of [[low vision]] or blindness. One such example is [[Bardet-Biedl syndrome]]. | Recent advances in [[genetic map|mapping]] the [[human genome]] have identified other genetic causes of [[low vision]] or blindness. One such example is [[Bardet-Biedl syndrome]]. | ||
===Poisoning=== | ====Poisoning==== | ||
A small portion of all cases of blindness are caused by the intake of certain chemicals. A well-known example is [[methanol]] <ref Name="Methanol">{{cite web | A small portion of all cases of blindness are caused by the intake of certain chemicals. A well-known example is [[methanol]] <ref Name="Methanol">{{cite web | ||
| title = Methanol | | title = Methanol | ||
| Line 45: | Line 48: | ||
, found in [[methylated spirits]], which are sometimes used by [[Alcoholism|alcoholics]] as a cheap substitute for regular [[alcoholic beverages]]. | , found in [[methylated spirits]], which are sometimes used by [[Alcoholism|alcoholics]] as a cheap substitute for regular [[alcoholic beverages]]. | ||
===Willful | ====Willful Actions==== | ||
Blinding has been used as an act of vengeance and [[torture]] in some instances, to deprive a person of a major sense by which they can navigate or interact within the world, act fully independently, and be aware of events surrounding them. An example from the classical realm is Oedipus, who gouges out his own eyes after realizing that he fulfilled the awful prophecy spoken of him. | Blinding has been used as an act of vengeance and [[torture]] in some instances, to deprive a person of a major sense by which they can navigate or interact within the world, act fully independently, and be aware of events surrounding them. An example from the classical realm is Oedipus, who gouges out his own eyes after realizing that he fulfilled the awful prophecy spoken of him. | ||
====Drugs==== | |||
*[[Cidofovir]] | |||
*[[Ezogabine]] | |||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
{{WikiDoc Help Menu}} | |||
{{WikiDoc Sources}} | |||
[[Category:Blindness]] | [[Category:Blindness]] | ||
[[Category:Needs overview]] | [[Category:Needs overview]] | ||
[[Category:Needs content]] | [[Category:Needs content]] | ||
Latest revision as of 20:39, 29 July 2020
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Saumya Easaw, M.B.B.S.[2]
Causes
Common Causes
Serious visual impairment has a variety of causes:
Diseases
Most visual impairment is caused by disease and malnutrition. According to WHO estimates in 2002, the most common causes of blindness around the world are:
- cataracts (47.8%),
- glaucoma (12.3%),
- uveitis (10.2%),
- age-related macular degeneration (AMD) (8.7%),
- trachoma (3.6%),
- corneal opacity (5.1%), and
- diabetic retinopathy (4.8%), among other causes.
- Medications- Dexamethasone
People in developing countries are significantly more likely to experience visual impairment as a consequence of treatable or preventable conditions than are their counterparts in the developed world. While vision impairment is most common in people over age 60 across all regions, children in poorer communities are more likely to be affected by blinding diseases than are their more affluent peers.
The link between poverty and treatable visual impairment is most obvious when conducting regional comparisons of cause. Most adult visual impairment in North America and Western Europe is related to age-related macular degeneration and diabetic retinopathy. While both of these conditions are subject to treatment, neither can be cured. Another common cause is retinopathy of prematurity.
In developing countries, wherein people have shorter life expectancies, cataracts and water-borne parasites—both of which can be treated effectively—are most often the culprits (see River blindness, for example). Of the estimated 40 million blind people located around the world, 70–80% can have some or all of their sight restored through treatment.
In developed countries where parasitic diseases are less common and cataract surgery is more available, age-related macular degeneration, glaucoma, and diabetic retinopathy are usually the leading causes of blindness[1].
Abnormalities and Injuries
Eye injuries, most often occurring in people under 30, are the leading cause of monocular blindness (vision loss in one eye) throughout the United States. Injuries and cataracts affect the eye itself, while abnormalities such as optic nerve hypoplasia affect the nerve bundle that sends signals from the eye to the back of the brain, which can lead to decreased visual acuity.
People with injuries to the occipital lobe of the brain can, despite having undamaged eyes and optic nerves, still be legally or totally blind.
Genetic Defects
People with albinism often suffer from visual impairment to the extent that many are legally blind, though few of them actually cannot see. Leber's congenital amaurosis can cause total blindness or severe sight loss from birth or early childhood.
Recent advances in mapping the human genome have identified other genetic causes of low vision or blindness. One such example is Bardet-Biedl syndrome.
Poisoning
A small portion of all cases of blindness are caused by the intake of certain chemicals. A well-known example is methanol [2] , found in methylated spirits, which are sometimes used by alcoholics as a cheap substitute for regular alcoholic beverages.
Willful Actions
Blinding has been used as an act of vengeance and torture in some instances, to deprive a person of a major sense by which they can navigate or interact within the world, act fully independently, and be aware of events surrounding them. An example from the classical realm is Oedipus, who gouges out his own eyes after realizing that he fulfilled the awful prophecy spoken of him.
Drugs
References
- ↑ Bunce C, Wormald R. "Leading Causes of Certification for Blindness and Partial Sight in England & Wales." BMC Public Health. 2006 Mar 8;6(1):58 [Epub ahead of print]. PMID 16524463.
- ↑ "Methanol" (Web). Symptoms of Methanol Poisoning. Canada Safety Council. 2005. Retrieved March 27, 2007.