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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mugilan Poongkunran M.B.B.S [2]
Overview
Left upper quadrant pain can originate from the chest, diaphragm, abdomen, peritoneum or general medical conditions. Abdominal causes are generally due to the pathology involving spleen, stomach (also presents as epigastric and back pain), pancreas (usually present with epigastric and back pain), splenic flexure of the left colon (may have low abdominal pain or left flank pain) and left kidney (flank pain). Pain originating from intra-abdominal organ pathology may not localize accurately and diaphragmatic pain can be referred to the shoulder tip.
Causes
Life Threatening Causes
Life-threatening causes include conditions which may result in death or permanent disability within 24 hours if left untreated.
Causes of left upper quadrant abdominal pain developed by WikiDoc.org
Common Causes
Causes of left upper quadrant abdominal pain developed by WikiDoc.org
Causes by Organ System
| Cardiovascular
|
Abdominal aortic aneurysm rupture, infective endocarditis, intestinal lymphangiectasia, ischemic colitis, malignant hypertension, mesenteric artery ischemia, pulmonary arteriovenous malformations, pulmonary embolism, pulmonary infarction, purulent pericarditis, rheumatoid vasculitis, splenic artery aneurysm, splenic artery embolization, splenic infarction, systemic vasculitis
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| Chemical/Poisoning
|
Algal toxin in shellfish, aluminum toxicity, arsenic poisoning, cadmium toxicity, chromium poisoning, copper poisoning, ecstasy overdose, ethylene glycol poisoning, food poisoning, gold, iron poisoning, lead poisoning, mercury poisoning, methanol, organophosphate poisoning, saw palmetto, silver poisoning, toxic mushrooms
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| Dental
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No underlying causes
|
| Dermatologic
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Scarlet fever, scleroderma, shingles
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| Drug Side Effect
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Aspirin, colchicine toxicity, diclofenac, didanosine, fentanyl toxicity, hydroxyurea, ibuprofen, indomethacin, malignant hyperthermia, nonsteroidal anti-inflammatory drugs (NSAIDs), propylthiouracil, Reye's syndrome, statins, steroid abuse, thrombolytic therapy, tramadol toxicity, vitamin D toxicity
|
| Ear Nose Throat
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No underlying causes
|
| Endocrine
|
Addisonian crisis, adrenal hemorrhage, adrenal tuberculosis, carcinoid, diabetic ketoacidosis, multiple endocrine neoplasia type 1, Zollinger-Ellison syndrome
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| Environmental
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Organophosphate poisoning, saw palmetto
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| Gastroenterologic
|
Abdominal compartment syndrome, acute diverticulitis, acute pancreatitis, atraumatic splenic rupture, autoimmune pancreatitis, Bannayan-Zonana syndrome, bile reflux disease, bulimia nervosa, celiac disease, chronic constipation, collagenous colitis, colon cancer, colonic lymphoma, congestive splenomegaly, Crohn's disease, cystic metastasis to the spleen, eosinophilic gastroenteritis, familial adenomatous polyposis, Felty's syndrome, gastric carcinoma, gastrinoma, gastritis, gastroenteritis, Gaucher disease, hepatorenal syndrome, hiatus hernia, intestinal pseudo-obstruction, intussusception, irritable bowel syndrome, ischemic colitis, malignant peritoneal mesothelioma, milk-alkali syndrome, Ménétrier's disease, pancreatic cystic neoplasms, pancreatic tail cancer, peptic ulcer disease, perforated gastric ulcer, peritonitis, pernicious anemia, polycystic kidney disease with splenic cysts, porphyria, pseudocysts cystic splenosis, scarlet fever, scleroderma, somatostatinoma, splenic abscess, splenic infarction, splenic laceration and trauma, splenic lymphoma, splenosis, stress ulcer, subphrenic abscess, traumatic splenic rupture, typhoid fever, ulcerative colitis, visceral hamartoma, visceral hemangioma, volvulus, wandering spleen syndrome, Zollinger-Ellison syndrome
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| Genetic
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Beta thalassemia major, colon atresia, cystic fibrosis, Dent's disease, familial adenomatous polyposis, Gaucher disease, hereditary angio-oedema, Meckel syndrome, polycystic kidney disease with splenic cysts, porphyria, primary hyperoxaluria, sickle cell anemia, Von Hippel-Lindau disease, WAGR syndrome, Williams syndrome
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| Hematologic
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Acquired hemolytic anemia, antiphospholipid syndrome, beta thalassemia major, chronic lymphocytic leukemia, chronic myeloid leukemia, cryoglobulinemia, essential thrombocytosis, hairy cell leukemia, hereditary spherocytosis, lymphoma, MALT lymphoma, mastocytosis, myelofibrosis, plasma cell leukemia, polycythemia vera, porphyria, sickle cell anemia, Sézary syndrome, Waldenstrom macroglobulinemia
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| Iatrogenic
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Chromoendoscopy, cryoablation, exercise-induced gastrointestinal bleeding, gas following laparoscopy, gastric surgery, intra abdominal adhesions, large volume thoracentesis, magnetic resonance cholangiopancreatography, milk-alkali syndrome, nasogastric tubes, pancreaticoduodenectomy (Whipple procedure), percutaneous abdominal biopsy, peritoneal dialysis, post-ERCP perforation, post-traumatic cysts, radiation therapy, referred pain, splenic artery embolization
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| Infectious Disease
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Amebic dysentery, babesiosis, bacillary dysentery, botryomycosis, gastroenteritis, helicobacter pylori infection, histoplasmosis, infectious mononucleosis, infective endocarditis, inflammatory pleural effusions, intestinal worm infestation, kala-azar (visceral leishmaniasis), malaria, mediterranean spotted fever, miliary tuberculosis, mumps, mycobacterium avium complex, perinephric abscess, peritonitis, pneumonia, post streptococcal glomerulonephritis, purulent pericarditis, pyelonephritis, renal abscess, renal mucormycosis, renal tuberculosis, shingles, splenic abscess, splenic hydatid cyst, subphrenic abscess, tropical splenomegaly syndrome, typhoid fever, viral hemorrhagic fever, Weil syndrome, yellow fever
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| Musculoskeletal/Orthopedic
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Rib fracture, polymyositis
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| Neurologic
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Meckel syndrome
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| Nutritional/Metabolic
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Carbohydrate-deficient glycoprotein syndrome, cystinuria, Gaucher Disease, homocystinuria, hyperuricaemia, oxalosis
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| Obstetric/Gynecologic
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Eclampsia, endometriosis, gestational trophoblastic disease
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| Oncologic
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Bannayan-Zonana syndrome, chronic lymphocytic leukemia, chronic myeloid leukemia, colon cancer, colonic lymphoma, cystic metastasis to the spleen, Denys-Drash syndrome, essential thrombocytosis, familial adenomatous polyposis, gastric carcinoma, gastrinoma, hairy cell leukemia, malignant peritoneal mesothelioma, MALT lymphoma, mastocytosis, myelofibrosis, Ménétrier's disease, pancreatic tail cancer, plasma cell leukemia, polycythemia vera, renal angiosarcoma, renal cell carcinoma, somatostatinoma, splenic lymphoma, Sézary syndrome, tuberous sclerosis, tumor lysis syndrome, visceral hamartoma, visceral hemangioma, Von Hippel-Lindau disease, WAGR syndrome, Waldenstrom macroglobulinemia, Wilms tumor
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| Ophthalmologic
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No underlying causes
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| Overdose/Toxicity
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Cocaine overdose, contrast agents, fentanyl toxicity, steroid abuse, tramadol toxicity
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| Psychiatric
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Bulimia nervosa, intestinal pseudo-obstruction, irritable bowel syndrome, stress ulcer
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| Pulmonary
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Empyema, inflammatory pleural effusions, pneumonia, pulmonary arteriovenous malformations, pulmonary embolism, pulmonary infarction, systemic lupus erythematosus, Wegener's granulomatosis
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| Renal/Electrolyte
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Dent's disease, Denys-Drash syndrome, glomerulonephritis, Meckel syndrome, medullary cystic kidney disease, nephrocalcinosis, perinephric abscess, polycystic kidney disease with splenic cysts, pyelonephritis, renal angiosarcoma, renal cell carcinoma, renal mucormycosis, renal tuberculosis, renal tubular acidosis, scleroderma, systemic lupus erythematosus, tuberous sclerosis, tubulointerstitial nephritis, urinary outflow obstruction, Von Hippel-Lindau disease, WAGR syndrome, Wegener's granulomatosis, Weil syndrome, Williams syndrome, Wilms tumor, xanthogranulomatous pyelonephritis
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| Rheumatology/Immunology/Allergy
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Allergic gastroenteropathy, autoimmune gastritis, autoimmune pancreatitis, crohn's disease, cryoglobulinemia, Felty's syndrome, food intolerance, hereditary angio-oedema, pernicious anemia, Reye's syndrome, rheumatoid vasculitis, scarlet fever, systemic lupus erythematosus, systemic vasculitis, ulcerative colitis, Wegener's granulomatosis
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| Sexual
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Denys-Drash syndrome
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| Trauma
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Electrical burns, rib fractures, splenic laceration and hematoma, traumatic splenic rupture
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| Urologic
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No underlying causes
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| Miscellaneous
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Alcohol ingestion, chronic constipation, excessive caffeine, idiopathic, spicy food, splenosis
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Causes of left upper quadrant abdominal pain developed by WikiDoc.org
Causes in Alphabetical Order
Causes of left upper quadrant abdominal pain developed by WikiDoc.org
References
Template:Gastroenterology
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