Congenital syphilis screening: Difference between revisions

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__NOTOC__
__NOTOC__
{{congenital syphilis}}
{{congenital syphilis}}
{{CMG}}; {{AE}} {{ADI}}
{{CMG}}; {{AE}} {{ADI}} {{AKI}}
==Overview==
==Overview==
 
Routine [[antenatal]] screening is recommended for [[syphilis]].
Routine screening of newborn [[serum]] or [[umbilical cord]] [[blood]] is not recommended. Serologic testing of the mother’s serum is preferred rather than testing of the infant’s serum.


==Screening==
==Screening==
* Newborn serum is not used for serologic tests instead mother's serum is prefered. <ref name="urlCDC - Diseases Characterized by Genital, Anal, or Perianal Ulcers - 2010 STD Treatment Guidelines">{{cite web |url=http://www.cdc.gov/std/treatment/2010/genital-ulcers.htm#congenital |title=CDC - Diseases Characterized by Genital, Anal, or Perianal Ulcers - 2010 STD Treatment Guidelines |format= |work= |accessdate=2012-12-20}}</ref>
Effective prevention and detection of congenital syphilis depends on the identification of [[syphilis]] in [[pregnant]] women and screening is a key component to decrease the incidence of congenital syphilis. The recommendations for screening are as follows:<ref name=syphilis>https://www.uspreventiveservicestaskforce.org/Page/Document/RecommendationStatementFinal/syphilis-infection-in-pregnancy-screening Accessed on september 27,2016</ref><ref name=cdc2015>http://www.cdc.gov/std/tg2015/references.htm#424 Accessed on September 27, 2016</ref>
* The serologic tests performed on infant serum can be nonreactive if the mother’s serologic test result is of low titer or the mother was infected late in pregnancy.
{| border="1"
* Screening can be performed using either a nontreponemal or treponemal test. If either screening test is positive, testing must be performed immediately using the other complimentary test (i.e., nontreponemal test followed by treponemal test or vice-versa).
|-
* No infant or mother should leave the hospital unless maternal serologic status has been documented at least once during [[pregnancy]]; in communities and populations in which the risk for congenital syphilis is high, documentation should also occur at delivery.
!
!'''Screening Recommendations'''
|-
!'''Timing of Screening'''
|Test all [[pregnant]] women at the first [[prenatal]] visit.                                                                                                               
|-
!'''Screening Tests'''
|  
*Nontreponemal tests commonly used for initial screening include:
**[[Venereal Disease Research Laboratory ]][[(VDRL)]]
**[[Rapid Plasma Reagin]] (RPR)
If screening tests are positive confirmatory tests should be done
*Confirmatory tests include:
**[[Fluorescent treponemal antibody absorbed]] [[(FTA-ABS)]]
**[[Treponema pallidum particle agglutination]] [[(TPPA)]]
|-
!'''High Risk Population'''
|
*Most organizations recommend testing high-risk women again during the [[third trimester]] and at [[delivery]].<br>Groups at increased risk include:
**Uninsured women
**Women living in poverty
**Sex workers
**Illicit drug users
**Those diagnosed with other [[sexually transmitted diseases]] ([[STD]])
**Other women living in communities with high [[syphilis]] [[morbidity]]
|}


==References==
==References==
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{{reflist|2}}
{{reflist|2}}


[[Category:Disease]]
[[Category:Disease]]
[[Category:Neonatology]]
[[Category:Neonatology]]
[[Category:Pediatrics]]
[[Category:Pediatrics]]
[[Category:Grammar]]
[[Category:Emergency medicine]]
[[Category:Up-To-Date]]
[[Category:Infectious disease]]
[[Category:Infectious disease]]
[[Category:Grammar]]
[[Category:Obstetrics]]

Latest revision as of 21:04, 29 July 2020

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aditya Govindavarjhulla, M.B.B.S. [2] Aravind Kuchkuntla, M.B.B.S[3]

Overview

Routine antenatal screening is recommended for syphilis.

Screening

Effective prevention and detection of congenital syphilis depends on the identification of syphilis in pregnant women and screening is a key component to decrease the incidence of congenital syphilis. The recommendations for screening are as follows:[1][2]

Screening Recommendations
Timing of Screening Test all pregnant women at the first prenatal visit.
Screening Tests

If screening tests are positive confirmatory tests should be done

High Risk Population

References

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