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__NOTOC__
__NOTOC__
{{Infobox_Disease |
  Name          = {{PAGENAME}} |
  Image          = Filariasis 01.jpg |
}}
{{Filariasis}}
{{Filariasis}}
'''For patient information, click [[Filariasis (patient information)|here]]'''


{{CMG}}
'''For patient information, click [[Filariasis (patient information)|here]].'''
 
{{CMG}}; {{AE}} {{AEL}}
 
{{SK}} Filarial elephantiasis


==[[Filariasis overview|Overview]]==
==[[Filariasis overview|Overview]]==


==[[Filariasis historical perspective|Historical Perspective]]==
==[[Filariasis historical perspective|Historical Perspective]]==
==[[Filariasis classification|Classification]]==


==[[Filariasis pathophysiology|Pathophysiology]]==
==[[Filariasis pathophysiology|Pathophysiology]]==
Line 20: Line 21:


==[[Filariasis epidemiology and demographics|Epidemiology and Demographics]]==
==[[Filariasis epidemiology and demographics|Epidemiology and Demographics]]==
==[[Filariasis risk factors|Risk factors]]==
==[[Filariasis screening|Screening]]==


==[[Filariasis natural history, complications and prognosis|Natural History, Complications and Prognosis]]==
==[[Filariasis natural history, complications and prognosis|Natural History, Complications and Prognosis]]==
==Diagnosis==
==Diagnosis==
[[Filariasis history and symptoms| History and Symptoms]] | [[Filariasis physical examination | Physical Examination]] | [[Filariasis laboratory findings|Laboratory Findings]] | [[Filariasis other diagnostic studies|Other Diagnostic Studies]]
[[Filariasis history and symptoms| History and Symptoms]] | [[Filariasis physical examination | Physical Examination]] | [[Filariasis laboratory findings|Laboratory Findings]] | [[Filariasis X ray|Xray]] | [[Filariasis CT scan|CT scan]] | [[Filariasis MRI|MRI]] | [[Filariasis ultrasound|Ultrasound]] | [[Filariasis other imaging findings|Other imaging findings]] | [[Filariasis other diagnostic studies|Other Diagnostic Studies]]


==Treatment==
==Treatment==
[[Filariasis medical therapy|Medical Therapy]] | [[Filariasis primary prevention|Primary Prevention]] | [[Filariasis cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Filariasis future or investigational therapies|Future or Investigational Therapies]]
[[Filariasis medical therapy|Medical Therapy]] | [[Filariasis surgery|Surgery]] | [[Filariasis primary prevention|Primary Prevention]] | [[Filariasis secondary prevention|Secondary prevention]] | [[Filariasis cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Filariasis future or investigational therapies|Future or Investigational Therapies]]
===Antimicrobial therapy===
:* '''Filariasis treatment'''
::* 1. '''Lymphatic filariasis - Wuchereria bancrofti, Brugia malayi Brugia timori'''<ref name="pmid20739055">{{cite journal| author=Taylor MJ, Hoerauf A, Bockarie M| title=Lymphatic filariasis and onchocerciasis. | journal=Lancet | year= 2010 | volume= 376 | issue= 9747 | pages= 1175-85 | pmid=20739055 | doi=10.1016/S0140-6736(10)60586-7 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20739055  }} </ref><ref name="pmid22632644">{{cite journal| author=Knopp S, Steinmann P, Hatz C, Keiser J, Utzinger J| title=Nematode infections: filariases. | journal=Infect Dis Clin North Am | year= 2012 | volume= 26 | issue= 2 | pages= 359-81 | pmid=22632644 | doi=10.1016/j.idc.2012.02.005 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22632644  }} </ref>
:::* Preferred regimen: [[Diethylcarbamazine]] 6 mg/day PO qd for 12 days (single dose if patient will continue to live in endemic area or is younger than 9 years old) {{with or without}} [[Albendazole]] 400 mg PO qd
:::* Alternative regimen: [[Doxycycline]] 200 mg/day for 4 weeks {{withorwithout}} [[Ivermectin]] 150 μg/kg single dose (do not administer [[Ivermectin]] if there's a risk of serious adverse effects in areas where Loa loa is coendemic)
:::* Note: Do not administer [[Diethylcarbamazine]] where onchocerciasis is endemic due to the risk of causing severe local inflammation in patients with ocular microfilariae.
::* 2. '''Cutaneous filariasis - Onchocercia volvulus, Loa loa'''<ref name="pmid20739055">{{cite journal| author=Taylor MJ, Hoerauf A, Bockarie M| title=Lymphatic filariasis and onchocerciasis. | journal=Lancet | year= 2010 | volume= 376 | issue= 9747 | pages= 1175-85 | pmid=20739055 | doi=10.1016/S0140-6736(10)60586-7 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20739055  }} </ref><ref name="pmid22632644">{{cite journal| author=Knopp S, Steinmann P, Hatz C, Keiser J, Utzinger J| title=Nematode infections: filariases. | journal=Infect Dis Clin North Am | year= 2012 | volume= 26 | issue= 2 | pages= 359-81 | pmid=22632644 | doi=10.1016/j.idc.2012.02.005 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22632644  }} </ref>
:::* Preferred regimen (1): [[Doxycycline]] 150 μg/kg single dose
:::* Preferred regimen (2): ([[Doxycycline]] 100 mg PO qd for 6 weeks {{or}} 200 mg PO qd for 4 weeks) {{then}} [[Ivermectin]] after 4-6 months 150 μg/kg single dose
:::* Preferred regimen (3): [[Doxycycline]] 200 mg PO qd for 6 weeks {{then}} [[Ivermectin]] after 4-6 months 150 μg/kg single dose


==Case Studies==
==Case Studies==
[[Filariasis case study one|Case #1]]
[[Filariasis case study one|Case #1]]
{{Helminthiases}}


[[ar:فلاريا]]
==Related Chapters==
[[de:Filariose]]
* [[Brugia malayi]]
[[es:Filariasis]]
* [[Brugia timori]]
[[fr:Filariose]]
* [[Loa loa filaria]]
[[it:Filariosi]]
* [[Mansonella ozzardi]]
[[ms:Penyakit Untut]]
* [[Mansonella perstans]]
[[ja:フィラリア]]
* [[Mansonella streptocerca]]
[[nl:Filariasis]]
* [[Onchocerca volvulus]]
[[pt:Filaríase]]
* [[Wuchereria bancrofti]]
[[sk:Vlásovce]]
[[wa:fiyaires]]


[[Category:Parasitic diseases]]
{{Helminthiases}}
[[Category:Neglected diseases]]
[[Category:Infectious disease]]


[[Category:Emergency mdicine]]
[[Category:Disease]]
[[Category:Disease]]
 
[[Category:Up-To-Date]]
{{WikiDoc Help Menu}}
[[Category:Infectious disease]]
{{WikiDoc Sources}}
[[Category:Vascular medicine]]
 
[[Category:Urology]]
==References==
[[Category:Gastroenterology]]
{{reflist|2}}

Latest revision as of 21:45, 29 July 2020

Filariasis Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Filariasis from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms

Physical Examination

Laboratory Findings

X Ray

CT Scan

MRI

Ultrasound

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Filariasis On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

slides

Images

American Roentgen Ray Society Images of Filariasis

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Filariasis

on Filariasis

Filariasis in the news

Blogs on Filariasis

Directions to Hospitals Treating Filariasis

Risk calculators and risk factors for Filariasis

For patient information, click here.

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmed Elsaiey, MBBCH [2]

Synonyms and keywords: Filarial elephantiasis

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Filariasis from other Diseases

Epidemiology and Demographics

Risk factors

Screening

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms | Physical Examination | Laboratory Findings | Xray | CT scan | MRI | Ultrasound | Other imaging findings | Other Diagnostic Studies

Treatment

Medical Therapy | Surgery | Primary Prevention | Secondary prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies

Case Studies

Case #1

Related Chapters

Template:Helminthiases