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{{Infobox_Disease |
__NOTOC__
  Name          = Hematemesis |
'''For patient information, click [[{{PAGENAME}} (patient information)|here]]'''
  Image          = |
{{Hematemesis}}
  Caption        = |
{{CMG}}; {{JFS}}
  DiseasesDB    = 30745 |
  ICD10          = {{ICD10|K|92|0|k|92}} |
  ICD9          = {{ICD9|578.0}} |
  ICDO          = |
  OMIM          = |
  MedlinePlus    = |
  eMedicineSubj  = med |
  eMedicineTopic = 3565 |
  MeshName      = Hematemesis |
  MeshNumber    = C23.550.414.788.400 |
}}
{{SI}}
{{CMG}}
{{JFS}}
{{Editor Help}}


==Overview==
{{SK}} Vomiting of blood; haematemesis; blood in the vomit, bloody vomiting


'''Hematemesis''' or '''haematemesis''' is the [[vomiting]] of [[blood]]. The source is generally the upper [[gastrointestinal tract]]. Patients can easily confuse it with [[hemoptysis]] (coughing up blood), although the former is more common.
==[[Hematemesis overview|Overview]]==


==Signs==
==[[Hematemesis historical perspective|Historical Perspective]]==
Signs of the onset of hematemesis may include:
* A history of [[alcohol abuse|excessive alcohol use]] or [[liver disease]]
* Any esophogastric symptoms, such as nausea or vomiting
* Brown or black blood
* Blood that looks like coffee grounds
* Dark colored, tar like stools (a condition known as [[melena]])


===Complete Differential Diagnosis of the Causes of hematmesis===
==[[Hematemesis classification|Classification]]==
(In alphabetical order)


*[[Abciximab]]
==[[Hematemesis pathophysiology|Pathophysiology]]==
*[[Acute esophageal necrosis (AEN)]]
*[[Adenocarcinoma ]]
*[[Alendronate]]
*[[Angiodysplasia]]
*[[Angiomas]]
*[[Aortic Coarctation]]
*[[Aortoenteric fistula]]
Arterial, venous, or other vascular malformations
*[[Aspirin]]
*[[Blue rubber bleb nevus syndrome]]
*[[Candida albicans]]
*[[Carcinoid]]
*[[Caustic ingestion]]
*[[Clopidogrel ]]
*[[Coagulopathy]]
*[[Congenital malformations]]
*[[Coumarin]]
*[[Cow's milk allergy]]
*[[Crimean-Congo hemorrhagic fever]]
*[[Cytomegalovirus]]
*[[Dieulafoy's lesion]]
*[[Disseminated intravascular coagulation]]
*[[Drotrecogin alfa]]
*[[Drug-induced thrombocytopenia]]
*[[Duodenal varices]]
*[[Duplication cysts]]
*[[Ehlers-Danlos syndrome]]
*[[Esophageal cancer]]
*[[Esophageal dilatation]]
*[[Esophageal melanosis ]]
*[[Esophagitis]]
*[[Foreign body ingestion]]
*[[Gastric varices]]
*[[Helicobacter pylori]]
*[[Hemobilia]]
*[[Hemophilia]]
*[[Hemosuccus pancreaticus]]
*[[Hereditary hemorrhagic telangiectasia ]]
*[[Herpes simplex virus]]
*[[Heterotopic pancreatic tissue]]
*[[Idiopathic]]
*[[Idiopathic thrombocytopenic purpura ]]
*[[Intestinal duplication]]
*[[Kaposi's sarcoma]]
*[[Kasabach-Merritt syndromes]]
*[[Leiomyoma]]
*[[Lipoma]]
*[[Lymphoma]]
*[[Mallory-Weiss syndrome]]
*[[Melanoma]]
*[[Melanoma]]
*[[Metastatic tumor]]
*[[Munchausen syndrome by proxy]]
*[[Nonsteroidal antiinflammatory drugs]]
*[[Osler-Weber-Rendu syndrome]]
*[[Parasites]]
*[[Peptic ulcer disease]]
*[[Pill-induced]]
*[[Polyp (hyperplastic, adenomatous, hamartomatous)]]
*[[Portal hypertension]]
*[[Portal hypertensive gastropathy]]
*[[Post gastric/duodenal polypectomy]]
*[[Post-surgical anastamosis]]
*[[Potassium chloride]]
*[[Pseudomembranous esophagitis ]]
*[[Quinidine]]
*[[Radiation-induced telangiectasia]]
*[[Rift valley fever]]
*[[Schistosomiasis]]
*[[Sibutramine]]
*[[Stress-induced ulcer]]
*[[Systemic mastocytosis]]
*[[Tetracycline]]
*[[Ticlopidine]]
*[[Traumatic or post-surgical]]
*[[Vasculitis,]]
*[[Von Willebrand disease ]]
*[[Watermelon stomach (gastric antral vascular ectasia)]]
*[[Zollinger Ellison syndrome]]


===Complete Differential Diagnosis of the Causes of hematmesis===
==[[Hematemesis causes|Causes]]==
(By organ system)
{|style="width:80%; height:100px" border="1"
|style="height:100px"; style="width:25%" border="1" bgcolor="LightSteelBlue" | '''Cardiovascular'''
|style="height:100px"; style="width:75%" border="1" bgcolor="Beige" | No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Chemical / poisoning'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Dermatologic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Drug Side Effect'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Ear Nose Throat'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Endocrine'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Environmental'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Gastroenterologic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Genetic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Hematologic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Iatrogenic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Infectious Disease'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Musculoskeletal / Ortho'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Neurologic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Nutritional / Metabolic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Obstetric/Gynecologic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Oncologic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Opthalmologic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Overdose / Toxicity'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Psychiatric'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Pulmonary'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Renal / Electrolyte'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Rheum / Immune / Allergy'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Sexual'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Trauma'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Urologic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Miscellaneous'''
|bgcolor="Beige"| No underlying causes
|-
|}


==[[Hematemesis differential diagnosis|Differentiating Hematemesis from other Diseases]]==


==[[Hematemesis epidemiology and demographics|Epidemiology and Demographics]]==


==Management==
==[[Hematemesis risk factors|Risk Factors]]==
[[Hematemesis]] is treated as a [[medical emergency]]. The most vital distinction is whether there is blood loss sufficient to cause [[Shock (medical)|shock]].


===Minimal blood loss===
==[[Hematemesis screening|Screening]]==
If this is not the case, the patient is generally administered a [[proton pump inhibitor]] (e.g. [[omeprazole]]), given [[blood transfusion]]s (if the level of [[hemoglobin]] is extremely low, that is less than 8.0 g/dL or 4.5-5.0 mmol/L), and kept [[nil per os]] until pneumonoultramicroscopic silivolcano coniosis (coniosis) can be arranged. Adequate venous access (large-bore [[cannula]]s or a [[central venous catheter]]) is generally obtained in case the patient suffers a further bleed and becomes unstable.


===Significant blood loss===
==[[Hematemesis natural history, complications and prognosis|Natural History, Complications and Prognosis]]==
In a "hemodynamically significant" case of hematemesis, that is [[hypovolemic shock]], resuscitation is an immediate priority to prevent [[cardiac arrest]]. Fluids and/or blood is administered, preferably by central venous catheter, and the patient is prepared for emergency endoscopy, which is typically done in theatres. [[Surgery|Surgical]] opinion is usually sought in case the source of bleeding cannot be identified endoscopically, and [[laparotomy]] is necessary.


==References==
==Diagnosis==
{{Reflist|2}}


== See also ==
[[Hematemesis history and symptoms|History and Symptoms]] | [[Hematemesis physical examination|Physical Examination]] | [[Hematemesis laboratory findings|Laboratory Findings]] | [[Hematemesis CT|CT]] | [[Hematemesis MRI|MRI]] | [[Hematemesis other imaging findings|Other Imaging Findings]] | [[Hematemesis other diagnostic studies|Other Diagnostic Studies]]
* [[Upper gastrointestinal bleeding]]
* [[Shock (medical)|Shock]]
* [[Melena]]


==External links==
==Treatment==
[[Hematemesis medical therapy|Medical Therapy]] | [[Hematemesis surgery|Surgery]] | [[Hematemesis primary prevention|Primary Prevention]] | [[Hematemesis secondary prevention|Secondary Prevention]] | [[Hematemesis cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Hematemesis future or investigational therapies|Future or Investigational Therapies]]


* [http://www.umm.edu/ency/article/003118.htm]
==Case Studies==
* [http://www.nlm.nih.gov/medlineplus/ency/article/003118.htm NIH/Medline]
[[Hematemesis case study one|Case #1]]


{{Gastroenterology}}
==External Links==
{{SIB}}
* [http://www.nlm.nih.gov/medlineplus/ency/article/003118.htm Vomiting blood - NIH/Medline ]




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Latest revision as of 22:01, 29 July 2020

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Hematemesis Microchapters

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Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Hematemesis from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms

Physical Examination

Laboratory Findings

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CT

MRI

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Treatment

Medical Therapy

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Case #1

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor-In-Chief: John Fani Srour, M.D.

Synonyms and keywords: Vomiting of blood; haematemesis; blood in the vomit, bloody vomiting

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Hematemesis from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms | Physical Examination | Laboratory Findings | CT | MRI | Other Imaging Findings | Other Diagnostic Studies

Treatment

Medical Therapy | Surgery | Primary Prevention | Secondary Prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies

Case Studies

Case #1

External Links

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