Prostatitis natural history, complications and prognosis: Difference between revisions
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__NOTOC__ | __NOTOC__ | ||
{{Prostatitis}} | {{Prostatitis}} | ||
{{CMG}} {{AE}} {{Maliha}} | {{CMG}} {{AE}} {{Maliha}}, {{USAMA}} | ||
==Overview== | ==Overview== | ||
If left untreated, patients with acute bacterial prostatitis may progress to develop prostatic abscess, [[septicemia]], urosepsis, and urinary retention.<ref name="pmid22031609">{{cite journal| author=Nickel JC| title=Prostatitis. | journal=Can Urol Assoc J | year= 2011 | volume= 5 | issue= 5 | pages= 306-15 | pmid=22031609 | doi=10.5489/cuaj.11211 | pmc=PMC3202001 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22031609 }} </ref><ref name="pmid10933636">{{cite journal| author=Naber KG, Weidner W| title=Chronic prostatitis-an infectious disease? | journal=J Antimicrob Chemother | year= 2000 | volume= 46 | issue= 2 | pages= 157-61 | pmid=10933636 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10933636 }} </ref> Patients with untreated chronic prostatitis may develop chronic pelvic pain, sexual dysfunction, [[infertility]], urinary frequency and urgency, and recurrent [[urinary tract infection]]s.<ref name="pmid10933636">{{cite journal| author=Naber KG, Weidner W| title=Chronic prostatitis-an infectious disease? | journal=J Antimicrob Chemother | year= 2000 | volume= 46 | issue= 2 | pages= 157-61 | pmid=10933636 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10933636 }} </ref><ref name="pmid17050893">{{cite journal| author=Schaeffer AJ| title=Clinical practice. Chronic prostatitis and the chronic pelvic pain syndrome. | journal=N Engl J Med | year= 2006 | volume= 355 | issue= 16 | pages= 1690-8 | pmid=17050893 | doi=10.1056/NEJMcp060423 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17050893 }} </ref> | If left untreated, patients with acute bacterial prostatitis may progress to develop prostatic abscess, [[septicemia]], urosepsis, and urinary retention.<ref name="pmid22031609">{{cite journal| author=Nickel JC| title=Prostatitis. | journal=Can Urol Assoc J | year= 2011 | volume= 5 | issue= 5 | pages= 306-15 | pmid=22031609 | doi=10.5489/cuaj.11211 | pmc=PMC3202001 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22031609 }} </ref><ref name="pmid10933636">{{cite journal| author=Naber KG, Weidner W| title=Chronic prostatitis-an infectious disease? | journal=J Antimicrob Chemother | year= 2000 | volume= 46 | issue= 2 | pages= 157-61 | pmid=10933636 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10933636 }} </ref> Patients with untreated chronic prostatitis may develop [[chronic pelvic pain]], [[sexual dysfunction]], [[infertility]], [[urinary frequency]] and [[Urinary urgency|urgency]], and recurrent [[urinary tract infection]]s.<ref name="pmid10933636">{{cite journal| author=Naber KG, Weidner W| title=Chronic prostatitis-an infectious disease? | journal=J Antimicrob Chemother | year= 2000 | volume= 46 | issue= 2 | pages= 157-61 | pmid=10933636 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10933636 }} </ref><ref name="pmid17050893">{{cite journal| author=Schaeffer AJ| title=Clinical practice. Chronic prostatitis and the chronic pelvic pain syndrome. | journal=N Engl J Med | year= 2006 | volume= 355 | issue= 16 | pages= 1690-8 | pmid=17050893 | doi=10.1056/NEJMcp060423 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17050893 }} </ref>Complete recovery without sequelae is usual among patients with acute prostatitis. Patients with chronic prostatitis have a gradual recovery and relapse is common.<ref name=nnn>Prostatitis. NHS 2016.http://www.nhs.uk/Conditions/Prostatitis/Pages/Introduction.aspx. Accessed on March 1, 2016</ref> | ||
==Natural history== | ==Natural history== | ||
If left untreated, patients with acute bacterial prostatitis may progress to develop:<ref name="pmid22031609">{{cite journal| author=Nickel JC| title=Prostatitis. | journal=Can Urol Assoc J | year= 2011 | volume= 5 | issue= 5 | pages= 306-15 | pmid=22031609 | doi=10.5489/cuaj.11211 | pmc=PMC3202001 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22031609 }} </ref><ref name="pmid10933636">{{cite journal| author=Naber KG, Weidner W| title=Chronic prostatitis-an infectious disease? | journal=J Antimicrob Chemother | year= 2000 | volume= 46 | issue= 2 | pages= 157-61 | pmid=10933636 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10933636 }} </ref> | If left untreated, patients with acute bacterial prostatitis may progress to develop:<ref name="pmid22031609">{{cite journal| author=Nickel JC| title=Prostatitis. | journal=Can Urol Assoc J | year= 2011 | volume= 5 | issue= 5 | pages= 306-15 | pmid=22031609 | doi=10.5489/cuaj.11211 | pmc=PMC3202001 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22031609 }} </ref><ref name="pmid10933636">{{cite journal| author=Naber KG, Weidner W| title=Chronic prostatitis-an infectious disease? | journal=J Antimicrob Chemother | year= 2000 | volume= 46 | issue= 2 | pages= 157-61 | pmid=10933636 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10933636 }} </ref><ref name="pmid20704171">{{cite journal| author=Sharp VJ, Takacs EB, Powell CR| title=Prostatitis: diagnosis and treatment. | journal=Am Fam Physician | year= 2010 | volume= 82 | issue= 4 | pages= 397-406 | pmid=20704171 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20704171 }} </ref> | ||
*Prostatic abscess | *Prostatic abscess | ||
*[[Septicemia]] | *[[Septicemia]] | ||
*Urosepsis | *Urosepsis | ||
*Urinary retention | *[[Urinary retention]] | ||
*Chronic prostatitis | |||
If left untreated, patients with chronic prostatitis may progress to develop:<ref name="pmid10933636">{{cite journal| author=Naber KG, Weidner W| title=Chronic prostatitis-an infectious disease? | journal=J Antimicrob Chemother | year= 2000 | volume= 46 | issue= 2 | pages= 157-61 | pmid=10933636 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10933636 }} </ref><ref name="pmid17050893">{{cite journal| author=Schaeffer AJ| title=Clinical practice. Chronic prostatitis and the chronic pelvic pain syndrome. | journal=N Engl J Med | year= 2006 | volume= 355 | issue= 16 | pages= 1690-8 | pmid=17050893 | doi=10.1056/NEJMcp060423 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17050893 }} </ref> | If left untreated, patients with chronic prostatitis may progress to develop:<ref name="pmid10933636">{{cite journal| author=Naber KG, Weidner W| title=Chronic prostatitis-an infectious disease? | journal=J Antimicrob Chemother | year= 2000 | volume= 46 | issue= 2 | pages= 157-61 | pmid=10933636 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10933636 }} </ref><ref name="pmid17050893">{{cite journal| author=Schaeffer AJ| title=Clinical practice. Chronic prostatitis and the chronic pelvic pain syndrome. | journal=N Engl J Med | year= 2006 | volume= 355 | issue= 16 | pages= 1690-8 | pmid=17050893 | doi=10.1056/NEJMcp060423 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17050893 }} </ref> | ||
*Chronic pelvic pain | *[[Chronic pelvic pain]] | ||
*Sexual dysfunction | *[[Sexual dysfunction]] | ||
*[[Infertility]] | *[[Infertility]] | ||
*Difficulty in urinating: frequency, urgency, [[dysuria]] | *Difficulty in urinating: [[frequency]], [[Urinary urgency|urgency]], [[dysuria]] | ||
*Recurrent [[urinary tract infection]]s | *Recurrent [[urinary tract infection]]s | ||
==Complications== | ==Complications== | ||
Common complications of prostatitis include<ref name="pmid22031609">{{cite journal| author=Nickel JC| title=Prostatitis. | journal=Can Urol Assoc J | year= 2011 | volume= 5 | issue= 5 | pages= 306-15 | pmid=22031609 | doi=10.5489/cuaj.11211 | pmc=PMC3202001 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22031609 }} </ref><ref name="pmid10933636">{{cite journal| author=Naber KG, Weidner W| title=Chronic prostatitis-an infectious disease? | journal=J Antimicrob Chemother | year= 2000 | volume= 46 | issue= 2 | pages= 157-61 | pmid=10933636 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10933636 }} </ref><ref name="pmid17050893">{{cite journal| author=Schaeffer AJ| title=Clinical practice. Chronic prostatitis and the chronic pelvic pain syndrome. | journal=N Engl J Med | year= 2006 | volume= 355 | issue= 16 | pages= 1690-8 | pmid=17050893 | doi=10.1056/NEJMcp060423 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17050893 }} </ref> | Common complications of prostatitis include<ref name="pmid22031609">{{cite journal| author=Nickel JC| title=Prostatitis. | journal=Can Urol Assoc J | year= 2011 | volume= 5 | issue= 5 | pages= 306-15 | pmid=22031609 | doi=10.5489/cuaj.11211 | pmc=PMC3202001 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22031609 }} </ref><ref name="pmid10933636">{{cite journal| author=Naber KG, Weidner W| title=Chronic prostatitis-an infectious disease? | journal=J Antimicrob Chemother | year= 2000 | volume= 46 | issue= 2 | pages= 157-61 | pmid=10933636 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10933636 }} </ref><ref name="pmid17050893">{{cite journal| author=Schaeffer AJ| title=Clinical practice. Chronic prostatitis and the chronic pelvic pain syndrome. | journal=N Engl J Med | year= 2006 | volume= 355 | issue= 16 | pages= 1690-8 | pmid=17050893 | doi=10.1056/NEJMcp060423 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17050893 }} </ref><ref>{{Cite journal | ||
| author = [[John N. Krieger]], [[Donald E. Riley]], [[Phaik Yeong Cheah]], [[Men Long Liong]] & [[Kah Hay Yuen]] | |||
| title = Epidemiology of prostatitis: new evidence for a world-wide problem | |||
| journal = [[World journal of urology]] | |||
| volume = 21 | |||
| issue = 2 | |||
| pages = 70–74 | |||
| year = 2003 | |||
| month = June | |||
| doi = 10.1007/s00345-003-0329-0 | |||
| pmid = 12712363 | |||
}}</ref><ref>{{Cite journal | |||
| author = [[Dong Sup Lee]], [[Hyun-Sop Choe]], [[Hee Youn Kim]], [[Sun Wook Kim]], [[Sang Rak Bae]], [[Byung Il Yoon]] & [[Seung-Ju Lee]] | |||
| title = Acute bacterial prostatitis and abscess formation | |||
| journal = [[BMC urology]] | |||
| volume = 16 | |||
| issue = 1 | |||
| pages = 38 | |||
| year = 2016 | |||
| month = July | |||
| doi = 10.1186/s12894-016-0153-7 | |||
| pmid = 27388006 | |||
}}</ref> | |||
*[[Urinary retention]] | *[[Urinary retention]] | ||
*[[Sepsis]] | *[[Sepsis]] | ||
*Prostatic abscess | *Prostatic [[abscess]] | ||
*Pelvic pain | *[[BPH]] | ||
*Metastatic infections such as pyogenic vertebral osteomyelitis | *[[Prostatic cancer]] | ||
* | *[[Pelvic pain]] | ||
*[[Metastatic]] infections such as pyogenic [[vertebral osteomyelitis]] | |||
*[[Erectile dysfunction]] | |||
*[[Infertility]] | |||
==Prognosis== | ==Prognosis== | ||
Patients with acute prostatitis usually recover completely, without a [[sequelae]]. Patients with chronic prostatitis gradually recover over time and with time, the rate of [[relapse]] is high, reaching up to 50%.<ref name=nnn>Prostatitis. NHS 2016.http://www.nhs.uk/Conditions/Prostatitis/Pages/Introduction.aspx. Accessed on March 1, 2016</ref> | |||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
{{WH}} | |||
{{WS}} | |||
[[Category:Inflammations]] | [[Category:Inflammations]] | ||
[[Category:Urology]] | [[Category:Urology]] | ||
[[Category:Andrology]] | [[Category:Andrology]] | ||
[[Category:Disease]] | [[Category:Disease]] | ||
Latest revision as of 23:51, 29 July 2020
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Maliha Shakil, M.D. [2], Usama Talib, BSc, MD [3]
Overview
If left untreated, patients with acute bacterial prostatitis may progress to develop prostatic abscess, septicemia, urosepsis, and urinary retention.[1][2] Patients with untreated chronic prostatitis may develop chronic pelvic pain, sexual dysfunction, infertility, urinary frequency and urgency, and recurrent urinary tract infections.[2][3]Complete recovery without sequelae is usual among patients with acute prostatitis. Patients with chronic prostatitis have a gradual recovery and relapse is common.[4]
Natural history
If left untreated, patients with acute bacterial prostatitis may progress to develop:[1][2][5]
- Prostatic abscess
- Septicemia
- Urosepsis
- Urinary retention
- Chronic prostatitis
If left untreated, patients with chronic prostatitis may progress to develop:[2][3]
- Chronic pelvic pain
- Sexual dysfunction
- Infertility
- Difficulty in urinating: frequency, urgency, dysuria
- Recurrent urinary tract infections
Complications
Common complications of prostatitis include[1][2][3][6][7]
- Urinary retention
- Sepsis
- Prostatic abscess
- BPH
- Prostatic cancer
- Pelvic pain
- Metastatic infections such as pyogenic vertebral osteomyelitis
- Erectile dysfunction
- Infertility
Prognosis
Patients with acute prostatitis usually recover completely, without a sequelae. Patients with chronic prostatitis gradually recover over time and with time, the rate of relapse is high, reaching up to 50%.[4]
References
- ↑ 1.0 1.1 1.2 Nickel JC (2011). "Prostatitis". Can Urol Assoc J. 5 (5): 306–15. doi:10.5489/cuaj.11211. PMC 3202001. PMID 22031609.
- ↑ 2.0 2.1 2.2 2.3 2.4 Naber KG, Weidner W (2000). "Chronic prostatitis-an infectious disease?". J Antimicrob Chemother. 46 (2): 157–61. PMID 10933636.
- ↑ 3.0 3.1 3.2 Schaeffer AJ (2006). "Clinical practice. Chronic prostatitis and the chronic pelvic pain syndrome". N Engl J Med. 355 (16): 1690–8. doi:10.1056/NEJMcp060423. PMID 17050893.
- ↑ 4.0 4.1 Prostatitis. NHS 2016.http://www.nhs.uk/Conditions/Prostatitis/Pages/Introduction.aspx. Accessed on March 1, 2016
- ↑ Sharp VJ, Takacs EB, Powell CR (2010). "Prostatitis: diagnosis and treatment". Am Fam Physician. 82 (4): 397–406. PMID 20704171.
- ↑ John N. Krieger, Donald E. Riley, Phaik Yeong Cheah, Men Long Liong & Kah Hay Yuen (2003). "Epidemiology of prostatitis: new evidence for a world-wide problem". World journal of urology. 21 (2): 70–74. doi:10.1007/s00345-003-0329-0. PMID 12712363. Unknown parameter
|month=
ignored (help) - ↑ Dong Sup Lee, Hyun-Sop Choe, Hee Youn Kim, Sun Wook Kim, Sang Rak Bae, Byung Il Yoon & Seung-Ju Lee (2016). "Acute bacterial prostatitis and abscess formation". BMC urology. 16 (1): 38. doi:10.1186/s12894-016-0153-7. PMID 27388006. Unknown parameter
|month=
ignored (help)