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| {{Idiopathic interstitial pneumonia}} | | {{Idiopathic interstitial pneumonia}} |
| {{CMG}}; {{AE}} {{AZ}}; {{Chetan}} | | {{CMG}}; {{AE}} {{AZ}}; {{Chetan}} |
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| ==Overview==
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| Repeated measurements of different clinical and physiological parameters are believed to be useful in assessing the clinical course of IPF. Assessment of dyspnea, using an established clinical scale for rating the impact of dyspnea on activities. <ref name="McSweeny-1995">{{Cite journal | last1 = McSweeny |first1 = AJ. | last2 = Creer | first2 = TL. | title = Health-related quality-of-life assessment in medical care. | journal = Dis Mon | volume = 41 | issue = 1 | pages = 1-71 | month = Jan | year = 1995 | doi = | PMID = 7805548 }}</ref> Lung volumes, DLCO, resting arterial blood gases, cardiopulmonary exercise testing with measurement of gas exchange, HRCT lung scans are our current tools for diagnosing [[idiopathic interstitial pneumonia]]. Physiologic testings have been used to determine the current functional lung capacity. Studies have shown that conventional lung function tests by spirometry have more precision in prognosis of patients with IPF, while extensive tests like gas exchange measurements at rest and exercise do not add additional information to make the prognostic or treatment evaluation more precise. <ref name="Erbes-1997">{{Cite journal | last1 = Erbes | first1 = R. | last2 = Schaberg | first2 = T. | last3 = Loddenkemper | first3 = R. | title = Lung function tests in patients with idiopathic pulmonary fibrosis. Are they helpful for predicting outcome? | journal = Chest | volume = 111 | issue = 1 | pages = 51-7 | month = Jan | year = 1997 | doi = | PMID = 8995992 }}</ref>.
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| ===Diagnosis===
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| The diagnostic criteria for
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| {|class="wikitable" width="60%"
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| | colspan="1" style="text-align:center; background:Beige"|'''AMERICAN THORACIC SOCIETY / EUROPEAN RESPIRATORY SOCIETY CRITERIA'''for diagnosing of '''IDIOPATHIC PULMONARY FIBROSIS''' in absence of surgical lung biopsy
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| | bgcolor="LightSteelBlue"|<nowiki>"</nowiki> '''Major criteria''':(must have all)<nowiki>"</nowiki>
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| :* Exclusion of other known causes of ILD, such as certain drug toxicities, environmental exposures, and connective tissue diseases
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| :* Abnormal pulmonary function studies that include evidence of restriction (reduced VC, often with an increased FEV1/FVC ratio) and impaired gas exchange (increased P[A-a]O2, decreased PaO2 with rest or exercise or decreased DLCO)
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| :* Bibasilar reticular abnormalities with minimal ground-glass opacities on HRCT scans
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| :* Transbronchial lung biopsy/BAL showing no features to support an alternative diagnosis
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| | bgcolor="LightSteelBlue"|<nowiki>"</nowiki> '''Minor criteria''':<nowiki>"</nowiki>
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| :* Age > 50 yr <BR>
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| :* Insidious onset of unexplained dyspnea on exertion <BR>
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| :* Duration illness > 3 mo <BR>
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| :* Bibasilar, inspiratory crackles <nowiki>"</nowiki>
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| |}
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| ==History and Symptoms== | | ==History and Symptoms== |