Brilinta tablet/contraindications: Difference between revisions
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'''History of Intracranial Hemorrhage''' | '''History of Intracranial Hemorrhage''' | ||
BRILINTA is contraindicated in patients with a history of [[intracranial hemorrhage]] (ICH) because of a high risk of recurrent ICH in this population see [[Brilinta tablet/clinical studies|Clinical Studies]]. | BRILINTA is contraindicated in patients with a history of [[intracranial hemorrhage]] (ICH) because of a high risk of recurrent ICH in this population ''(see [[Brilinta tablet/clinical studies|Clinical Studies]]).'' | ||
'''Active Bleeding''' | '''Active Bleeding''' | ||
BRILINTA is contraindicated in patients with active pathological bleeding such as peptic ulcer or intracranial hemorrhage [[Brilinta tablet/warnings|Warnings]] | BRILINTA is contraindicated in patients with active pathological bleeding such as peptic ulcer or [[intracranial hemorrhage]] ''(see [[Brilinta tablet/warnings|Warnings]] and [[Brilinta tablet/adverse reactions|Adverse Reactions]]).'' | ||
'''Severe Hepatic Impairment''' | '''Severe Hepatic Impairment''' | ||
BRILINTA is contraindicated in patients with severe hepatic impairment because of a probable increase in exposure, and it has not been studied in these patients. Severe hepatic impairment increases the risk of bleeding because of reduced synthesis of coagulation proteins see | BRILINTA is contraindicated in patients with severe [[hepatic impairment]] because of a probable increase in exposure, and it has not been studied in these patients. Severe [[hepatic impairment]] increases the risk of bleeding because of reduced synthesis of coagulation proteins (see | ||
[[Brilinta tablet/pharmacology|Pharmacology]]. | ''[[Brilinta tablet/pharmacology|Pharmacology]]).'' | ||
'''Hypersensivity''' | '''Hypersensivity''' | ||
BRILINTA is contraindicated in patients with hypersensitivity (e.g. angioedema) to ticagrelor or any component of the product see[[Brilinta tablet/Adverse Reactions|Adverse Reactions]<ref>{{Cite web | last = | first = | title = BRILINTA (TICAGRELOR) TABLET [ASTRAZENECA LP] | url = http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=f7b3f443-e83d-4bf2-0e96-023448fed9a8 | publisher = | date = | accessdate = 21 March 2014 }}</ref>. | BRILINTA is contraindicated in patients with hypersensitivity (e.g. angioedema) to ticagrelor or any component of the product ''(see [[Brilinta tablet/Adverse Reactions|Adverse Reactions]])''<ref>{{Cite web | last = | first = | title = BRILINTA (TICAGRELOR) TABLET [ASTRAZENECA LP] | url = http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=f7b3f443-e83d-4bf2-0e96-023448fed9a8 | publisher = | date = | accessdate = 21 March 2014 }}</ref>. | ||
{{DrugReflist}} | {{DrugReflist}} | ||
Latest revision as of 18:04, 21 March 2014
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Jesus Rosario Hernandez, M.D. [2]
Contraindications
History of Intracranial Hemorrhage
BRILINTA is contraindicated in patients with a history of intracranial hemorrhage (ICH) because of a high risk of recurrent ICH in this population (see Clinical Studies).
Active Bleeding
BRILINTA is contraindicated in patients with active pathological bleeding such as peptic ulcer or intracranial hemorrhage (see Warnings and Adverse Reactions).
Severe Hepatic Impairment
BRILINTA is contraindicated in patients with severe hepatic impairment because of a probable increase in exposure, and it has not been studied in these patients. Severe hepatic impairment increases the risk of bleeding because of reduced synthesis of coagulation proteins (see Pharmacology).
Hypersensivity
BRILINTA is contraindicated in patients with hypersensitivity (e.g. angioedema) to ticagrelor or any component of the product (see Adverse Reactions)[1].
References
- ↑ "BRILINTA (TICAGRELOR) TABLET [ASTRAZENECA LP]". Retrieved 21 March 2014.