Hypertrophic cardiomyopathy: Difference between revisions

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  | Image          = 2369.jpg
  | Image          = 2369.jpg
  | Caption        = Hypertrophic cardiomyopathy. <br> <small> [http://www.peir.net Image courtesy of Professor Peter Anderson DVM PhD and published with permission © PEIR, University of Alabama at Birmingham, Department of Pathology] </small>
  | Caption        = Hypertrophic cardiomyopathy. <br> <small> [http://www.peir.net Image courtesy of Professor Peter Anderson DVM PhD and published with permission © PEIR, University of Alabama at Birmingham, Department of Pathology] </small>
| DiseasesDB    = 6373
| ICD10          = {{ICD10|I|42|1|i|30}}-{{ICD10|I|42|2|i|30}}
| ICD9          = {{ICD9|425.4}}
| ICDO          =
| OMIM          =
| MedlinePlus    =
| MeshID        = D002312
}}
}}
{{Hypertrophic cardiomyopathy}}
{{Hypertrophic cardiomyopathy}}


'''Editor-In-Chief:''' [[C. Michael Gibson, M.S., M.D.]] [mailto:charlesmichaelgibson@gmail.com]
'''Editor-In-Chief:''' [[C. Michael Gibson, M.S., M.D.]] [mailto:charlesmichaelgibson@gmail.com] {{AE}} {{Soroush}}


{{SK}} Hypertrophic cardiomyopathy or HCM, Asymmetric septal hypertrophy or ASH, Hypertrophic obstructive cardiomyopathy, HOCM, Idiopathic hypertrophic subaortic stenosis or IHSS, familial isolated hypertrophic obstructive cardiomyopathy, familial isolated hypertrophic subaortic stenosis, familial or idiopathic hypertrophic subaortic stenosis, familial or idiopathic hypertrophic obstructive cardiomyopathy, primitive hypertrophic obstructive cardiomyopathy, primitive hypertrophic subaortic stenosis, muscular subaortic stenosis, apical hypertrophic cardiomyopathy, which is also known as nonobstructive hypertrophic cardiomyopathy and Japanese variant hypertrophic cardiomyopathy or the Yamaguchi variant (since the first cases described were all in individuals of Japanese descent)
{{SK}} Hypertrophic cardiomyopathy or HCM, Asymmetric septal hypertrophy or ASH, Hypertrophic obstructive cardiomyopathy, HOCM, Idiopathic hypertrophic subaortic stenosis or IHSS, familial isolated hypertrophic obstructive cardiomyopathy, familial isolated hypertrophic subaortic stenosis, familial hypertrophic subaortic stenosis, idiopathic hypertrophic subaortic stenosis, familial hypertrophic obstructive cardiomyopathy, idiopathic hypertrophic obstructive cardiomyopathy, primitive hypertrophic obstructive cardiomyopathy, primitive hypertrophic subaortic stenosis, muscular subaortic stenosis, apical hypertrophic cardiomyopathy, which is also known as nonobstructive hypertrophic cardiomyopathy and Japanese variant hypertrophic cardiomyopathy or Yamaguchi syndrome.


==[[Hypertrophic cardiomyopathy overview|Overview]]==
==[[Hypertrophic cardiomyopathy overview|Overview]]==
 
==[[Hypertrophic cardiomyopathy historical perspective|Historical Perspective]]==
==[[Hypertrophic cardiomyopathy classification|Classification]]==
==[[Hypertrophic cardiomyopathy classification|Classification]]==


==Pathophysiology==
==[[Hypertrophic cardiomyopathy pathophysiology|Pathophysiology]]==
[[Hypertrophic cardiomyopathy genetics|Genetics]] | [[Hypertrophic_cardiomyopathy_histopathology|Histopathologic Abnormalities]] | [[Hypertrophic cardiomyopathy anatomic abnormalities|Anatomic Abnormalities]] | [[Hypertrophic cardiomyopathy outflow obstruction|Outflow Obstruction]] | [[Hypertrophic cardiomyopathy ischemia|Ischemia]] |  [[Hypertrophic cardiomyopathy arrhythmogenesis|Arrhythmogenesis]]


==[[Hypertrophic cardiomyopathy epidemiology and demographics|Epidemiology and Demographcis]]==
==[[Hypertrophic cardiomyopathy differential diagnosis|Differentiating Hypertrophic Cardiomyopathy from Other Diseases]]==
==[[Hypertrophic cardiomyopathy causes|Causes]]==


==[[Hypertrophic cardiomyopathy epidemiology and demographics|Epidemiology and Demographics]]==
==[[Hypertrophic cardiomyopathy risk factors|Risk Factors]]==
==[[Hypertrophic cardiomyopathy screening|Screening]]==
==[[Hypertrophic cardiomyopathy screening|Screening]]==


==[[Hypertrophic cardiomyopathy differential diagnosis|Differentiating Hypertrophic Cardiomyopathy from other Diseases]]==


==[[Hypertrophic cardiomyopathy natural history|Natural History, Prognosis and Sudden Cardiac Death Risk]]==
==[[Hypertrophic cardiomyopathy natural history|Natural History, Complications and Prognosis]]==


==Diagnosis==
==Diagnosis==
[[Hypertrophic cardiomyopathy screening|Genetic Testing & Screening]] | [[Hypertrophic cardiomyopathy symptoms|History and Symptoms]] | [[Hypertrophic cardiomyopathy physical examination|Physical examination]] | [[Hypertrophic cardiomyopathy electrocardiogram|Electrocardiogram]] | [[Hypertrophic cardiomyopathy echocardiography|Echocardiography]] | [[Hypertrophic cardiomyopathy MRI|Cardiac MRI]] | [[Hypertrophic cardiomyopathy CT|Cardiac CT]] | [[Hypertrophic cardiomyopathy other imaging findings|Positron Emission Tomography]]
[[Hypertrophic cardiomyopathy diagnostic study of choice|Diagnostic Study of Choice]]| [[Hypertrophic cardiomyopathy symptoms|History and Symptoms]] | [[Hypertrophic cardiomyopathy physical examination|Physical examination]] | [[Hypertrophic cardiomyopathy laboratory findings|Laboratory findings]] | [[Hypertrophic cardiomyopathy electrocardiogram|Electrocardiogram]] | [[Hypertrophic cardiomyopathy x ray|X Ray]] | [[Hypertrophic cardiomyopathy echocardiography and ultrasound|Echocardiography and Ultrasound]] |  [[Hypertrophic cardiomyopathy CT scan|CT Scan]] | [[Hypertrophic cardiomyopathy MRI|MRI]] |[[Hypertrophic cardiomyopathy other imaging findings|Other Imaging Findings]] | [[Hypertrophic cardiomyopathy other diagnostic studies|Other Diagnostic Studies]].


==Treatment==
==Treatment==


*[[Hypertrophic cardiomyopathy treatment strategy|Treatment Strategy]]
*'''[[Hypertrophic cardiomyopathy medical therapy|Medical therapy]]''', '''[[Hypertrophic cardiomyopathy interventions|Interventions]], [[Hypertrophic cardiomyopathy surgery|Surgery]], [[Hypertrophic cardiomyopathy primary prevention|Primary Prevention]], [[Hypertrophic cardiomyopathy secondary prevention|Secondary Prevention]], Cost Effectiveness of Therapy, Future or Investigational Therapy'''<br />
 
*'''Medical therapy:''' [[Hypertrophic cardiomyopathy medical treatment#Simple Supportive Measures|Supportive Therapy]] | [[Hypertrophic cardiomyopathy medical treatment#Pharmacotherapy|Pharmacotherapy]]
 
*'''Invasive therapies:''' [[Hypertrophic cardiomyopathy alcohol septal ablation|Alcohol Septal Ablation]] | [[Hypertrophic cardiomyopathy septal myectomy|Septal Myectomy]] | [[Hypertrophic cardiomyopathy ventricular pacing|Ventricular Pacing]] | [[Hypertrophic cardiomyopathy automatic implantable cardiac defibrillator placement|Automatic Implantable Cardiac Defibrillator (AICD) Placement]] | [[Hypertrophic cardiomyopathy invasive therapy guidelines|Septal Reduction Therapy Guidelines]]
 
====Contraindicated medications====
{{MedCondContrAbs|MedCond =  Idiopathic hypertrophic subaortic stenosis.|Dobutamine}}
 
*[[Hypertrophic cardiomyopathy surgery#Cardiac transplantation|Cardiac transplantation]]
 
==Special Patient Populations==
[[Hypertrophic cardiomyopathy in special clinical scenarios#2011 ACCF/AHA Guideline Recommendations: Asymptomatic Patients (DO NOT EDIT)|Asymptomatic Patients]] | [[Hypertrophic cardiomyopathy management during childhood | Management During Childhood]] |  [[Hypertrophic cardiomyopathy in special clinical scenarios#Management of HCM in presence of hypotension and cardiovascular collapse|Hypotension/Cardiovascular collapse]] | [[Hypertrophic cardiomyopathy management during pregnancy|Pregnancy]]
 
==2011 ACCF/AHA Guideline Recommendations==
====Diagnostic testing:====
[[Hypertrophic cardiomyopathy electrocardiogram#2011 ACCF/AHA Guideline Recommendations: Electrocardiography  (DO NOT EDIT)|Electrocardiogram]]
| [[Hypertrophic cardiomyopathy echocardiography#2011 ACCF/AHA Guideline Recommendations: Echocardiography|Echocardiography]]
| [[Hypertrophic cardiomyopathy electrocardiogram#Stress Test|Stress Testing]]
| [[Hypertrophic_cardiomyopathy_MRI#2011_ACCF.2FAHA_Guideline_Recommendations:_Cardiac_Magnetic_Resonance|Cardiac Magnetic Resonance]]
| [[Hypertrophic_cardiomyopathy_CT#2011_ACCF.2FAHA_Guideline_Recommendations:_Detection_of_Concomitant_Coronary_Disease|Cardiac CT]]
| [[Hypertrophic cardiomyopathy other imaging findings#Positron Emission Tomography|Positron Emission Tomography]]
 
====Management:====
*'''Asymptomatic patients:''' [[Hypertrophic cardiomyopathy in special clinical scenarios#2011 ACCF/AHA Guideline Recommendations: Asymptomatic Patients (DO NOT EDIT) |Asymptomatic patients]]
 
*'''Symptomatic patints:''' [[Hypertrophic cardiomyopathy medical treatment#2011 ACCF/AHA Guideline Recommendations: Pharmacologic Management in Symptomatic Patients (DO NOT EDIT)|Pharmacologic Management]]
| [[Hypertrophic cardiomyopathy interventional cardiology|Invasive Therapies]]
| [[Hypertrophic cardiomyopathy alcohol septal ablation#2011 ACCF/AHA Guideline Recommendations: Alcohol Septal Ablation  (DO NOT EDIT)|Alcohol septal ablation]]
| [[Hypertrophic cardiomyopathy septal myectomy#2011 ACCF/AHA Guideline Recommendations: Septal Myectomy  (DO NOT EDIT)|Septal Myectomy]]
| [[Hypertrophic cardiomyopathy ventricular pacing#2011 ACCF/AHA Guideline Recommendations: Pacing (DO NOT EDIT)|Pacing]]
| [[Hypertrophic cardiomyopathy automatic implantable cardiac defibrillator placement#2011 ACCF/AHA Guideline Recommendations: Selection of Patients for ICDs (DO NOT EDIT)|Selection of Patients for ICDs]]
| [[Hypertrophic cardiomyopathy automatic implantable cardiac defibrillator placement#2011 ACCF/AHA Guideline Recommendations: Selection of ICD Device Type (DO NOT EDIT)|Selection of ICD-Device type]]
| [[Hypertrophic cardiomyopathy surgical treatment#Cardiac transplantation|Selection of Patients for Heart Transplantation]]
 
*'''Special Clinical Scenarios:''' [[Hypertrophic cardiomyopathy in special clinical scenarios#2011 ACCF/AHA Guideline Recommendations: Patients With LV Systolic Dysfunction (DO NOT EDIT)|Patients With LV Systolic Dysfunction]] | [[Hypertrophic cardiomyopathy risk factors for sudden death#2011 ACCF/AHA Guideline Recommendations: SCD Risk Stratification (DO NOT EDIT) |Sudden cardiac death Risk Stratification]] | [[Hypertrophic cardiomyopathy activities and circumstances to avoid#2011 AHA/ACC Guidelines Recommendations- Participation in Competitive or Recreational Sports and Physical Activity (DO NOT EDIT)|Participation in Competitive or Recreational Sports and Physical Activity]] | [[Hypertrophic cardiomyopathy medical treatment#2011 AHA/ACC Guidelines Recommendations- Management of Atrial Fibrillation in HCM (DO NOT EDIT)|Management of Atrial Fibrillation]] | [[Hypertrophic cardiomyopathy management during pregnancy#2011 ACCF/AHA Guideline Recommendations: Pregnancy/Delivery (DO NOT EDIT)|Pregnancy/Delivery]] | [[Hypertrophic cardiomyopathy with coronary artery disease#2011 ACCF/AHA Guideline Recommendations: Detection of Concomitant Coronary Disease (DO NOT EDIT)|Concomitant Coronary Disease]]
 
==Related Chapters==
* [[Aortic stenosis]]


==Resources==
==Resources==
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* [http://www.cardiomyopathy.org/ Cardiomyopathy Association]
* [http://www.cardiomyopathy.org/ Cardiomyopathy Association]
* [http://www.hcmresearchfoundation.org/ Hypertrophic Cardiomyopathy Research Foundation]
* [http://www.hcmresearchfoundation.org/ Hypertrophic Cardiomyopathy Research Foundation]
* [https://hcmcare.com HCM Care]


[[Category:Cardiomyopathy]]
[[Category:Cardiomyopathy]]

Latest revision as of 18:35, 11 March 2020

For patient information click here

Hypertrophic cardiomyopathy
Hypertrophic cardiomyopathy.
Image courtesy of Professor Peter Anderson DVM PhD and published with permission © PEIR, University of Alabama at Birmingham, Department of Pathology

Hypertrophic Cardiomyopathy Microchapters

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Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Hypertrophic Cardiomyopathy from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Study of Choice

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

X Ray

Echocardiography and Ultrasound

CT scan

MRI

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Interventions

Surgery

Primary Prevention

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Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

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Hypertrophic cardiomyopathy On the Web

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Risk calculators and risk factors for Hypertrophic cardiomyopathy

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Soroush Seifirad, M.D.[2]

Synonyms and keywords: Hypertrophic cardiomyopathy or HCM, Asymmetric septal hypertrophy or ASH, Hypertrophic obstructive cardiomyopathy, HOCM, Idiopathic hypertrophic subaortic stenosis or IHSS, familial isolated hypertrophic obstructive cardiomyopathy, familial isolated hypertrophic subaortic stenosis, familial hypertrophic subaortic stenosis, idiopathic hypertrophic subaortic stenosis, familial hypertrophic obstructive cardiomyopathy, idiopathic hypertrophic obstructive cardiomyopathy, primitive hypertrophic obstructive cardiomyopathy, primitive hypertrophic subaortic stenosis, muscular subaortic stenosis, apical hypertrophic cardiomyopathy, which is also known as nonobstructive hypertrophic cardiomyopathy and Japanese variant hypertrophic cardiomyopathy or Yamaguchi syndrome.

Overview

Historical Perspective

Classification

Pathophysiology

Differentiating Hypertrophic Cardiomyopathy from Other Diseases

Causes

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Study of Choice| History and Symptoms | Physical examination | Laboratory findings | Electrocardiogram | X Ray | Echocardiography and Ultrasound | CT Scan | MRI |Other Imaging Findings | Other Diagnostic Studies.

Treatment

Resources


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