Hearing impairment future or investigational therapies: Difference between revisions

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{{Hearing impairment}}
{{Hearing impairment}}
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'''Editor-In-Chief:''' [[C. Michael Gibson, M.S., M.D.|C. Michael Gibson, M.S., M.D]]. <nowiki>[[Mailto:charlesmichaelgibson@gmail.com|[1]]]</nowiki>; '''Associate Editor(s)-in-Chief:'''


==Future or Investigational Therapies==
==Overview==
Many hearing impaired individuals use certain assistive devices in their daily lives. Individuals can communicate by telephone using [[telecommunications devices for the deaf]] (TDD).  This device looks like a typewriter or word processor and transmits typed text over the telephone. Other names in common use are textphone and minicom. A videophone can be used for distance communication using sign language. In 2004, mobile textphone devices came onto the market for the first time allowing simultaneous two way text communication. In the U.S., the UK, the Netherlands and many other western countries there are telephone relay services so that a hearing impaired person can communicate with a hearing person via a human translator. Wireless, internet and mobile phone/SMS text messaging are beginning to take over the role of the TDD.  Other assistive devices include those that use flashing lights to signal events such as a ringing telephone, a doorbell, or a fire alarm.  Video conferencing is also a new technology that permits signed conversations as well as permitting an [[American sign language|ASL]]-English interpreter to voice and sign conversations between a hearing impaired and hearing person, negating the need to use a TTY or computer keyboard.
Use of [[somatic cell]] within the prospect of regrowth in [[Cochlea|cochlea cells]] is under study. The tablet-based automated [[audiometer]] presents a new method for threshold hearing assessment. Similarly [[Video conference|video conferencing]], [[Flashing light|flashing lights]] to signal events and other [[Telecommunication|telecommunications]] devices are under study.
==Gene therapy==
In 2005, there was success of the regrowth of cochlea cells in test subjects by a research team led by Dr. Yehoash Raphael from the University of Michigan.  This study was conducted using guinea pigs as test subjects.  [http://www.newscientist.com/article.ns?id=dn7003] It is important to note however, that the regrowth of cochlear hair cells does not imply the restoration of hearing sensitivity as the sensory cells may or may not make connections with neurons that carry the signals from hair cells to the brain.  


A team led by Dr. Stefan Heller from Stanford University are pioneering stem cell research in the prospect of regrowth in cochlea cells.[http://news-service.stanford.edu/news/2005/november16/med-heller-111605.html]
==Future or Investigational Therapies<ref name="pmid33253610">{{cite journal| author=Nieman CL, Oh ES| title=Hearing Loss. | journal=Ann Intern Med | year= 2020 | volume= 173 | issue= 11 | pages= ITC81-ITC96 | pmid=33253610 | doi=10.7326/AITC202012010 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=33253610  }}</ref><ref name="pmid28672306">{{cite journal| author=Reed NS, Betz J, Kendig N, Korczak M, Lin FR| title=Personal Sound Amplification Products vs a Conventional Hearing Aid for Speech Understanding in Noise. | journal=JAMA | year= 2017 | volume= 318 | issue= 1 | pages= 89-90 | pmid=28672306 | doi=10.1001/jama.2017.6905 | pmc=5817472 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=28672306  }}</ref><ref name="pmid26183518">{{cite journal| author=Thompson GP, Sladen DP, Borst BJ, Still OL| title=Accuracy of a Tablet Audiometer for Measuring Behavioral Hearing Thresholds in a Clinical Population. | journal=Otolaryngol Head Neck Surg | year= 2015 | volume= 153 | issue= 5 | pages= 838-42 | pmid=26183518 | doi=10.1177/0194599815593737 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26183518  }}</ref>==
 
*Many hearing-impaired individuals use certain assistive devices in their daily lives like [[hearing aid]], [[Hearing implant|hearing implants]], or [[telecommunication]].
 
*Individuals can communicate by different means like telephone using [[Telecommunication|telecommunications]] devices for the deaf. This device seems like a typewriter or word processing system and transmits typed text over the phone.
 
*A videophone is often used for distance communication using signing. Then mobile textphone devices came onto the marketplace for the primary time allowing simultaneous two-way text [[Communication Service for the Deaf|communication]]. In many western countries, there are [[Telephone call|telephone]] services so that a hearing-impaired person can communicate with a person who can hear through a human translator. Mobile phones, wireless, internet, and text messaging are starting to take over the role of telecommunications devices for the deaf.
 
*Other assistive devices include people who use flashing lights to signal events like a fireplace alarm, mobile vibrations, ringing a telephone, or a doorbell.
 
*Video conferencing is additionally a replacement technology that allows signed conversations also as permitting an English interpreter to voice and sign conversations between a person that can't hear and a hearing person, negating the necessity to use a keypad or any typing material.
*Prospective single-cohort concluded that the tablet-based automated [[audiometer]] presents a replacement method for threshold hearing assessment outside conventional sound booths. Testing with the tablet [[audiometer]] was conducted in a non-sound-treated room and characterized by the ambient [[noise]] level in the background.
 
===Gene therapy===
 
*There was the success of the regrowth of [[Cochlea|cochlea cells]] in test subjects by a research team in 2005. This study was conducted on pigs as test subjects. The conclusion of the research is important to note, however, that the [[regrowth]] of cochlear hair cells does not imply the restoration of hearing sensitivity as the sensory cells may not make connections with [[neurons]] that carry the signals from hair cells of cochlea in the inner ear to the temporal region of the [[brain]]. But further study is still going on.
 
*A team led by Stanford University is pioneering [[Somatic cells|somatic cell]] research within the prospect of regrowth in [[Cochlea|cochlea cells.]]


==References==
==References==
{{Reflist|2}}
{{Reflist|2}}
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[[Category:Primary care]]
[[Category:Geriatrics]]
[[Category:Geriatrics]]
[[Category:Communication disorders]]
[[Category:Communication disorders]]
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[[Category:Noise pollution]]
[[Category:Noise pollution]]
[[Category:Needs overview]]
[[Category:Needs overview]]
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Latest revision as of 07:58, 10 May 2021

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [[Mailto:charlesmichaelgibson@gmail.com|[1]]]; Associate Editor(s)-in-Chief:

Overview

Use of somatic cell within the prospect of regrowth in cochlea cells is under study. The tablet-based automated audiometer presents a new method for threshold hearing assessment. Similarly video conferencing, flashing lights to signal events and other telecommunications devices are under study.

Future or Investigational Therapies[1][2][3]

  • Individuals can communicate by different means like telephone using telecommunications devices for the deaf. This device seems like a typewriter or word processing system and transmits typed text over the phone.
  • A videophone is often used for distance communication using signing. Then mobile textphone devices came onto the marketplace for the primary time allowing simultaneous two-way text communication. In many western countries, there are telephone services so that a hearing-impaired person can communicate with a person who can hear through a human translator. Mobile phones, wireless, internet, and text messaging are starting to take over the role of telecommunications devices for the deaf.
  • Other assistive devices include people who use flashing lights to signal events like a fireplace alarm, mobile vibrations, ringing a telephone, or a doorbell.
  • Video conferencing is additionally a replacement technology that allows signed conversations also as permitting an English interpreter to voice and sign conversations between a person that can't hear and a hearing person, negating the necessity to use a keypad or any typing material.
  • Prospective single-cohort concluded that the tablet-based automated audiometer presents a replacement method for threshold hearing assessment outside conventional sound booths. Testing with the tablet audiometer was conducted in a non-sound-treated room and characterized by the ambient noise level in the background.

Gene therapy

  • There was the success of the regrowth of cochlea cells in test subjects by a research team in 2005. This study was conducted on pigs as test subjects. The conclusion of the research is important to note, however, that the regrowth of cochlear hair cells does not imply the restoration of hearing sensitivity as the sensory cells may not make connections with neurons that carry the signals from hair cells of cochlea in the inner ear to the temporal region of the brain. But further study is still going on.

References

  1. Nieman CL, Oh ES (2020). "Hearing Loss". Ann Intern Med. 173 (11): ITC81–ITC96. doi:10.7326/AITC202012010. PMID 33253610 Check |pmid= value (help).
  2. Reed NS, Betz J, Kendig N, Korczak M, Lin FR (2017). "Personal Sound Amplification Products vs a Conventional Hearing Aid for Speech Understanding in Noise". JAMA. 318 (1): 89–90. doi:10.1001/jama.2017.6905. PMC 5817472. PMID 28672306.
  3. Thompson GP, Sladen DP, Borst BJ, Still OL (2015). "Accuracy of a Tablet Audiometer for Measuring Behavioral Hearing Thresholds in a Clinical Population". Otolaryngol Head Neck Surg. 153 (5): 838–42. doi:10.1177/0194599815593737. PMID 26183518.

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