Cryoglobulinemia natural history, complications and prognosis: Difference between revisions
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{{Cryoglobulinemia}} | {{Cryoglobulinemia}} | ||
{{CMG}}; {{AE}} {{FT}} | |||
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==Overview== | ==Overview== | ||
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==Complications== | ==Complications== | ||
The complications of cryoglobulinemia are as follows: | |||
* | *Rapidly progressive [[neuropathy]] | ||
*Heart | * [[Congestive heart failure|Heart failure]] | ||
* | * Digital [[ischemia]] threatening amputation | ||
*[[ | * Diffuse [[Alveolus|alveolar]] [[Bleeding|hemorrhage]] resulting in [[hemoptysis]] | ||
*[[ | * [[Respiratory failure]] | ||
* | * [[Stroke]] | ||
* | * [[Chronic renal failure|End stage renal disease]] | ||
==Prognosis== | ==Prognosis== | ||
Patients having severe manifestations of the disease such as pulmonary vasculitis, end-stage renal disease, cardiac vasculitis and central nervous system vasculitis have generally poor prognosis of the disease. The prognosis of cryoglobulinemia depends on the organ system involved and varies accordingly. | |||
{| class="wikitable" | |||
!Organ system involved | |||
!Survival rate | |||
|- | |||
|[[Glomerular disease|Glomerulonephritis]] | |||
|79% | |||
|- | |||
|Pulmonary [[vasculitis]] | |||
|22% | |||
|- | |||
|Central nervous system [[vasculitis]] | |||
|66% | |||
|- | |||
|Gastrointestinal vasculitis | |||
|67% | |||
|- | |||
|Cardiac vasculitis | |||
|100% | |||
|} | |||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
[[Category:Needs content]] | [[Category:Needs content]] | ||
Latest revision as of 23:29, 30 April 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Feham Tariq, MD [2]
Overview
Natural History
Complications
The complications of cryoglobulinemia are as follows:
- Rapidly progressive neuropathy
- Heart failure
- Digital ischemia threatening amputation
- Diffuse alveolar hemorrhage resulting in hemoptysis
- Respiratory failure
- Stroke
- End stage renal disease
Prognosis
Patients having severe manifestations of the disease such as pulmonary vasculitis, end-stage renal disease, cardiac vasculitis and central nervous system vasculitis have generally poor prognosis of the disease. The prognosis of cryoglobulinemia depends on the organ system involved and varies accordingly.
| Organ system involved | Survival rate |
|---|---|
| Glomerulonephritis | 79% |
| Pulmonary vasculitis | 22% |
| Central nervous system vasculitis | 66% |
| Gastrointestinal vasculitis | 67% |
| Cardiac vasculitis | 100% |