Rhabdomyosarcoma laboratory findings: Difference between revisions
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{{Rhabdomyosarcoma}} | {{Rhabdomyosarcoma}} | ||
{{CMG}} | {{CMG}};{{AE}} {{S.M}} | ||
==Overview== | |||
The essential [[laboratory]] tests for [[patients]] with [[rhabdomyosarcoma]] are evaluation of [[CBC]], [[liver function tests]], [[renal function tests]], [[blood]] [[Electrolyte|electrolytes]], and [[coagulation]] studies. | |||
== Laboratory Findings== | |||
* The essential [[laboratory]] tests for [[patients]] with [[rhabdomyosarcoma]] are:<ref name="pmid10466447">{{cite journal| author=Fiegl M, Weltermann A, Stindl R, Fonatsch C, Lechner K, Gisslinger H| title=Massive disseminated intravascular coagulation and hyperfibrinolysis in alveolar rhabdomyosarcoma: case report and review of the literature. | journal=Ann Hematol | year= 1999 | volume= 78 | issue= 7 | pages= 335-8 | pmid=10466447 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10466447 }} </ref><ref name="pmid9703006">{{cite journal| author=Kawasaki H, Takayama J, Nagasaki K, Yamaguchi K, Ohira M| title=Hypercalcemia in children with rhabdomyosarcoma. | journal=J Pediatr Hematol Oncol | year= 1998 | volume= 20 | issue= 4 | pages= 327-9 | pmid=9703006 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9703006 }} </ref> | |||
** [[CBC]]: | |||
*** It may result into [[pancytopenia]] and [[anemia]] due to [[bone]] involvement. | |||
** [[Liver function test]] ( [[LFT]]): | |||
*** [[LFT]] should be evaluated before [[chemotherapy]] and for assessment of [[liver]] [[metastasis]]. | |||
** [[Renal function tests|Renal function test]]: | |||
*** [[BUN]] and [[creatinine]] levels should be evaluated before [[chemotherapy]]. | |||
** Blood [[Electrolyte|electrolytes]] such as [[sodium]], [[potassium]], [[chlorine]], [[calcium]], [[Phosphorous acid|phosphorous]], and [[magnesium]]: | |||
*** [[Hypercalcemia]] may occur. | |||
*** These tests should be evaluated before [[chemotherapy]]. | |||
** [[Coagulation]] studies: | |||
*** [[Disseminated intravascular coagulation]] may occur. | |||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
{{WH}} | {{WH}} | ||
{{WS}} | {{WS}} | ||
[[Category:Disease]] | [[Category:Disease]] | ||
[[Category:Up-To-Date]] | |||
[[Category:Oncology]] | [[Category:Oncology]] | ||
[[Category:Medicine]] | |||
[[Category:Orthopedics]] |
Latest revision as of 16:56, 8 March 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Shadan Mehraban, M.D.[2]
Overview
The essential laboratory tests for patients with rhabdomyosarcoma are evaluation of CBC, liver function tests, renal function tests, blood electrolytes, and coagulation studies.
Laboratory Findings
- The essential laboratory tests for patients with rhabdomyosarcoma are:[1][2]
- CBC:
- It may result into pancytopenia and anemia due to bone involvement.
- Liver function test ( LFT):
- LFT should be evaluated before chemotherapy and for assessment of liver metastasis.
- Renal function test:
- BUN and creatinine levels should be evaluated before chemotherapy.
- Blood electrolytes such as sodium, potassium, chlorine, calcium, phosphorous, and magnesium:
- Hypercalcemia may occur.
- These tests should be evaluated before chemotherapy.
- Coagulation studies:
- Disseminated intravascular coagulation may occur.
- CBC:
References
- ↑ Fiegl M, Weltermann A, Stindl R, Fonatsch C, Lechner K, Gisslinger H (1999). "Massive disseminated intravascular coagulation and hyperfibrinolysis in alveolar rhabdomyosarcoma: case report and review of the literature". Ann Hematol. 78 (7): 335–8. PMID 10466447.
- ↑ Kawasaki H, Takayama J, Nagasaki K, Yamaguchi K, Ohira M (1998). "Hypercalcemia in children with rhabdomyosarcoma". J Pediatr Hematol Oncol. 20 (4): 327–9. PMID 9703006.