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{{ Mantle cell lymphoma }}
{{Mantle cell lymphoma }}


{{CMG}}; {{AE}} {{AS}}
{{CMG}}; {{AE}} {{Akram}} {{AS}}
==Overview==
==Overview==
Common physical examination findings of mantle cell lymphoma include [[fever]], [[rash]], [[splenomegaly]], [[hepatomegaly]], [[Lymphadenopathy|peripheral lymphadenopathy]], and [[Lymphadenopathy|central lymphadenopathy]].
Common [[physical examination]] findings of Mantle cell lymphoma include [[fever]], [[rash]], [[splenomegaly]], [[hepatomegaly]], [[Lymphadenopathy|peripheral lymphadenopathy]], and [[Lymphadenopathy|central lymphadenopathy]].
==Physical Examination<ref name="seer">National Cancer Institute. Surveillance, Epidemiology, and End Results Program 2015. http://seer.cancer.gov</ref>==
==Physical Examination==
===Temperature===
===Temperature===
* [[Fever]] is often present  
* [[Fever]] may be present.<ref>{{Cite journal
| author = [[Arati A. Inamdar]], [[Andre Goy]], [[Nehad M. Ayoub]], [[Christen Attia]], [[Lucia Oton]], [[Varun Taruvai]], [[Mark Costales]], [[Yu-Ting Lin]], [[Andrew Pecora]] & [[K. Stephen Suh]]
| title = Mantle cell lymphoma in the era of precision medicine-diagnosis, biomarkers and therapeutic agents
| journal = [[Oncotarget]]
| volume = 7
| issue = 30
| pages = 48692–48731
| year = 2016
| month = July
| doi = 10.18632/oncotarget.8961
| pmid = 27119356
}}</ref>
===Skin===
===Skin===
* [[Rash]]  
* [[Rash]] <ref>{{Cite journal
| author = [[A. Pawarode]], [[M. R. Baer]], [[S. Padmanabhan]], [[P. K. Wallace]], [[M. Barcos]], [[S. N. J. Sait]], [[A. W. Block]], [[M. Wetzler]] & [[M. Battiwalla]]
| title = Simultaneous presentation of acute monoblastic leukemia and mantle cell lymphoma: case report and review of the literature
| journal = [[Leukemia & lymphoma]]
| volume = 46
| issue = 12
| pages = 1813–1818
| year = 2005
| month = December
| doi = 10.1080/10428190500244258
| pmid = 16263586
}}</ref>
===Neck===
===Neck===
* [[Lymphadenopathy|Cervical lymphadenopathy]]
* [[Lymphadenopathy|Cervical lymphadenopathy]]<ref>{{Cite journal
| author = [[Julie M. Vose]]
| title = Mantle cell lymphoma: 2017 update on diagnosis, risk-stratification, and clinical management
| journal = [[American journal of hematology]]
| volume = 92
| issue = 8
| pages = 806–813
| year = 2017
| month = August
| doi = 10.1002/ajh.24797
| pmid = 28699667
}}</ref>
   
===Thorax===
===Thorax===
* Thoracic masses suggestive of [[Lymphadenopathy|central lymphadenopathy]]
* Thoracic masses suggestive of [[Lymphadenopathy|central lymphadenopathy]]<ref>{{Cite journal
* Chest tenderness
| author = [[Julie M. Vose]]
| title = Mantle cell lymphoma: 2017 update on diagnosis, risk-stratification, and clinical management
| journal = [[American journal of hematology]]
| volume = 92
| issue = 8
| pages = 806–813
| year = 2017
| month = August
| doi = 10.1002/ajh.24797
| pmid = 28699667
}}</ref>
===Abdomen===
===Abdomen===
* [[Abdominal mass]]es suggestive of [[Lymphadenopathy|central lymphadenopathy]]
* [[Abdominal mass]]es suggestive of [[Lymphadenopathy|central lymphadenopathy]]
* [[Splenomegaly]]  
* [[Splenomegaly]]<ref>{{Cite journal
| author = [[S. Pittaluga]], [[G. Verhoef]], [[A. Criel]], [[I. Wlodarska]], [[J. Dierlamm]], [[C. Mecucci]], [[H. Van den Berghe]] & [[C. De Wolf-Peeters]]
| title = "Small" B-cell non-Hodgkin's lymphomas with splenomegaly at presentation are either mantle cell lymphoma or marginal zone cell lymphoma. A study based on histology, cytology, immunohistochemistry, and cytogenetic analysis
| journal = [[The American journal of surgical pathology]]
| volume = 20
| issue = 2
| pages = 211–223
| year = 1996
| month = February
| pmid = 8554111
}}</ref>
* [[Hepatomegaly]]  
* [[Hepatomegaly]]  
* Abdominal tenderness  
* Abdominal tenderness  
===Extremities===
===Extremities===
* [[Lymphadenopathy|Peripheral lymphadenopathy]]
* [[Lymphadenopathy|Peripheral lymphadenopathy]]<ref>{{Cite journal
* Bone tenderness
| author = [[Julie M. Vose]]
| title = Mantle cell lymphoma: 2017 update on diagnosis, risk-stratification, and clinical management
| journal = [[American journal of hematology]]
| volume = 92
| issue = 8
| pages = 806–813
| year = 2017
| month = August
| doi = 10.1002/ajh.24797
| pmid = 28699667
}}</ref>
* Bone tenderness<ref>{{Cite journal
| author = [[Peng Yang]], [[Jun Lin]], [[Hao Liu]], [[Hao Shen]] & [[Hui-Lin Yang]]
| title = Primary bone mantle cell lymphomas with multiple vertebral compression fractures: A case report
| journal = [[Oncology letters]]
| volume = 13
| issue = 3
| pages = 1288–1292
| year = 2017
| month = March
| doi = 10.3892/ol.2017.5553
| pmid = 28454248
}}</ref>


==References==
==References==
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[[Category:Up-To-Date]]
[[Category:Oncology]]
[[Category:Medicine]]
[[Category:Hematology]]
[[Category:Immunology]]

Latest revision as of 05:24, 4 January 2019

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ali Akram, M.B.B.S.[2] Sowminya Arikapudi, M.B,B.S. [3]

Overview

Common physical examination findings of Mantle cell lymphoma include fever, rash, splenomegaly, hepatomegaly, peripheral lymphadenopathy, and central lymphadenopathy.

Physical Examination

Temperature

Skin

Neck

Thorax

Abdomen

Extremities

References

  1. ↑ Arati A. Inamdar, Andre Goy, Nehad M. Ayoub, Christen Attia, Lucia Oton, Varun Taruvai, Mark Costales, Yu-Ting Lin, Andrew Pecora & K. Stephen Suh (2016). "Mantle cell lymphoma in the era of precision medicine-diagnosis, biomarkers and therapeutic agents". Oncotarget. 7 (30): 48692–48731. doi:10.18632/oncotarget.8961. PMID 27119356. Unknown parameter |month= ignored (help)
  2. ↑ A. Pawarode, M. R. Baer, S. Padmanabhan, P. K. Wallace, M. Barcos, S. N. J. Sait, A. W. Block, M. Wetzler & M. Battiwalla (2005). "Simultaneous presentation of acute monoblastic leukemia and mantle cell lymphoma: case report and review of the literature". Leukemia & lymphoma. 46 (12): 1813–1818. doi:10.1080/10428190500244258. PMID 16263586. Unknown parameter |month= ignored (help)
  3. ↑ Julie M. Vose (2017). "Mantle cell lymphoma: 2017 update on diagnosis, risk-stratification, and clinical management". American journal of hematology. 92 (8): 806–813. doi:10.1002/ajh.24797. PMID 28699667. Unknown parameter |month= ignored (help)
  4. ↑ Julie M. Vose (2017). "Mantle cell lymphoma: 2017 update on diagnosis, risk-stratification, and clinical management". American journal of hematology. 92 (8): 806–813. doi:10.1002/ajh.24797. PMID 28699667. Unknown parameter |month= ignored (help)
  5. ↑ S. Pittaluga, G. Verhoef, A. Criel, I. Wlodarska, J. Dierlamm, C. Mecucci, H. Van den Berghe & C. De Wolf-Peeters (1996). ""Small" B-cell non-Hodgkin's lymphomas with splenomegaly at presentation are either mantle cell lymphoma or marginal zone cell lymphoma. A study based on histology, cytology, immunohistochemistry, and cytogenetic analysis". The American journal of surgical pathology. 20 (2): 211–223. PMID 8554111. Unknown parameter |month= ignored (help)
  6. ↑ Julie M. Vose (2017). "Mantle cell lymphoma: 2017 update on diagnosis, risk-stratification, and clinical management". American journal of hematology. 92 (8): 806–813. doi:10.1002/ajh.24797. PMID 28699667. Unknown parameter |month= ignored (help)
  7. ↑ Peng Yang, Jun Lin, Hao Liu, Hao Shen & Hui-Lin Yang (2017). "Primary bone mantle cell lymphomas with multiple vertebral compression fractures: A case report". Oncology letters. 13 (3): 1288–1292. doi:10.3892/ol.2017.5553. PMID 28454248. Unknown parameter |month= ignored (help)

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