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{{Esophagitis}}
{{Esophagitis}}
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==Overview==
==Overview==
Common risk factors in the development of esophagitis are [[immunosuppression]], alcohol use, [[smoking]], [[excessive vomiting]], certain medications, and surgery or [[radiation]] to the chest.
Common risk factors in the development of esophagitis are [[immunosuppression]], alcohol use, [[smoking]], [[excessive vomiting]], certain medications, and surgery or [[radiation]] to the chest.
==Risk Factors==
==Risk Factors==
The following increase the risk of esophagitis:
===Eosinophilic Esophagitis===
Common risk factors in the development of EoE include:<ref name="urlGenetic dissection of eosinophilic esophagitis provides insight into disease pathogenesis and treatment strategies. - PubMed - NCBI">{{cite web |url=https://www.ncbi.nlm.nih.gov/pubmed/21570716 |title=Genetic dissection of eosinophilic esophagitis provides insight into disease pathogenesis and treatment strategies. - PubMed - NCBI |format= |work= |accessdate=}}</ref><ref name="urlwww.ncbi.nlm.nih.gov">{{cite web |url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3129465/pdf/nihms290904.pdf |title=www.ncbi.nlm.nih.gov |format= |work= |accessdate=}}</ref><ref name="urlGenetics of Eosinophilic Esophagitis - FullText - Digestive Diseases 2014, Vol. 32, No. 1-2 - Karger Publishers">{{cite web |url=https://www.karger.com/Article/FullText/357005 |title=Genetics of Eosinophilic Esophagitis - FullText - Digestive Diseases 2014, Vol. 32, No. 1-2 - Karger Publishers |format= |work= |accessdate=}}</ref><ref name="pmid26488694">{{cite journal |vauthors=Furuta GT, Katzka DA |title=Eosinophilic Esophagitis |journal=N. Engl. J. Med. |volume=373 |issue=17 |pages=1640–8 |year=2015 |pmid=26488694 |pmc=4905697 |doi=10.1056/NEJMra1502863 |url=}}</ref><ref name="pmid26027600">{{cite journal |vauthors=Kocsis D, Tulassay Z, Juhász M |title=[Dietary and pharmacological aspects of eosinophilic esophagitis] |language=Hungarian |journal=Orv Hetil |volume=156 |issue=23 |pages=927–32 |year=2015 |pmid=26027600 |doi=10.1556/650.2015.30164 |url=}}</ref><ref name="pmid25396005">{{cite journal| author=Jarosz M, Taraszewska A| title=Risk factors for gastroesophageal reflux disease: the role of diet. | journal=Prz Gastroenterol | year= 2014 | volume= 9 | issue= 5 | pages= 297-301 | pmid=25396005 | doi=10.5114/pg.2014.46166 | pmc=4223119 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25396005  }}</ref>
*Age- EoE has a bimodal age distribution common in both children and adults.
*Sex- Males are more prone to EoE than the females.
*Weather- Cold and dry climate trigger EoE.
*Location- EoE is common in people with a history of European ancestry.
*Season- Summer and fall, this is because people stay outdoors during this time and the higher levels of the [[pollen]] and the other [[allergens]] during these seasons.
*Family history- EoE runs in the family and it is more common in people with a positive family history of the EoE.
*History of allergies- EoE is very common in patient with a history of allergies such as [[asthma]], industrial exposures, environmental allergies, chronic respiratory disease, food allergies and [[atopic dermatitis]].


* [[Alcohol]] use
===Reflux Esophagitis===
* [[Cigarette smoking]]
Common risk factors in the development  of reflux esophagitis include:
* Surgery or [[radiation]] to the chest (for example, treatment for lung cancer)
*[[Smoking]]
* Taking certain medications without plenty of water especially [[Alendronate]], [[Tetracycline]], [[Doxycycline]], and vitamins
*[[Obesity]]
* [[Vomiting]]
*[[Pregnancy]]
*[[Hiatal hernia]]
*[[Scleroderma]]
*[[Alcohol]] consumption
*Consuming drinks that contain [[caffeine]]  


Individuals with weakened immune systems due to HIV and certain medications (such as [[corticosteroids]]) may develop infections that lead to esophagitis.
*[[Medications]]:
:* [[Anticholinergics]] (e.g. for [[seasickness]])
:* [[Beta blockers]] for high [[blood pressure]] or [[heart disease]]
:* [[Bronchodilators]] for [[asthma]]
:* [[Calcium channel blocker|Calcium channel blockers]] for [[high blood pressure]]
:* [[Dopamine]]-active drugs for [[Parkinson's disease]]
:* [[Progestin]] for abnormal [[menstrual bleeding]] or birth control
:* [[Sedatives]] for [[insomnia]] or [[anxiety]]
:* [[Tricyclic antidepressants]]


==References==
==References==
{{reflist|2}}
{{reflist|2}}
{{WH}}
{{WS}}


[[Category:Primary care]]
[[Category:Gastroenterology]]
[[Category:Gastroenterology]]
[[Category:Inflammations]]
[[Category:Histopathology]]
[[Category:Disease]]
[[Category:Disease]]
{{WH}}
{{WS}}

Latest revision as of 21:41, 29 July 2020

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Ajay Gade MD[2]]

Overview

Common risk factors in the development of esophagitis are immunosuppression, alcohol use, smoking, excessive vomiting, certain medications, and surgery or radiation to the chest.

Risk Factors

Eosinophilic Esophagitis

Common risk factors in the development of EoE include:[1][2][3][4][5][6]

  • Age- EoE has a bimodal age distribution common in both children and adults.
  • Sex- Males are more prone to EoE than the females.
  • Weather- Cold and dry climate trigger EoE.
  • Location- EoE is common in people with a history of European ancestry.
  • Season- Summer and fall, this is because people stay outdoors during this time and the higher levels of the pollen and the other allergens during these seasons.
  • Family history- EoE runs in the family and it is more common in people with a positive family history of the EoE.
  • History of allergies- EoE is very common in patient with a history of allergies such as asthma, industrial exposures, environmental allergies, chronic respiratory disease, food allergies and atopic dermatitis.

Reflux Esophagitis

Common risk factors in the development of reflux esophagitis include:

References

  1. "Genetic dissection of eosinophilic esophagitis provides insight into disease pathogenesis and treatment strategies. - PubMed - NCBI".
  2. "www.ncbi.nlm.nih.gov" (PDF).
  3. "Genetics of Eosinophilic Esophagitis - FullText - Digestive Diseases 2014, Vol. 32, No. 1-2 - Karger Publishers".
  4. Furuta GT, Katzka DA (2015). "Eosinophilic Esophagitis". N. Engl. J. Med. 373 (17): 1640–8. doi:10.1056/NEJMra1502863. PMC 4905697. PMID 26488694.
  5. Kocsis D, Tulassay Z, Juhász M (2015). "[Dietary and pharmacological aspects of eosinophilic esophagitis]". Orv Hetil (in Hungarian). 156 (23): 927–32. doi:10.1556/650.2015.30164. PMID 26027600.
  6. Jarosz M, Taraszewska A (2014). "Risk factors for gastroesophageal reflux disease: the role of diet". Prz Gastroenterol. 9 (5): 297–301. doi:10.5114/pg.2014.46166. PMC 4223119. PMID 25396005.

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