Prolactinoma classification: Difference between revisions

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{{Prolactinoma}}
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==Overview==
==Overview==
 
[[Prolactinoma]] can be classified based upon either size or local invasion. Based on size, a prolactinoma can be classified as a microprolactinoma (<10 mm diameter) or macroprolactinoma (>10 mm diameter).
Based on size, a prolactinoma can be classified as a ''microprolactinoma'' (<10 mm diameter) or ''macroprolactinoma'' (>10 mm diameter).


==Classification==
==Classification==
Based on size, a prolactinoma can be classified as:
Prolactinoma may be classified based on either size or local invasion.
 
*''microprolactinoma'' (<10 mm diameter)
 
*''macroprolactinoma'' (>10 mm diameter).
 
The radiographical classification for pituitary adenomas is as follows:
 
*0: Normal pituitary appearance.
 
*I:                          Enclosed within the sella turcica, microadenoma, smaller than 10 mm.


*II: Enclosed within the sella turcica, macroadenoma, 10 mm or larger.
{|
 
! colspan="4" style="background: #4479BA; text-align: center;" |{{fontcolor|#FFF| Classification of prolactinoma}}
*III: Invasive, locally, into the sella.
|-
 
! colspan="2" style="background: #7d7d7d; text-align: center;" |{{fontcolor|#FFF|Classification basis}}
*IV: Invasive, diffusely, into the sella.
! style="background: #7d7d7d; text-align: center;" |{{fontcolor|#FFF|Type/Grade}}
 
! style="background: #7d7d7d; text-align: center;" |{{fontcolor|#FFF|Criteria}}
The grading schema for suprasellar extensions is as follows:
|-
 
| colspan="2" rowspan= "2" style="background: #DCDCDC; text-align: center;" |Classification based on size<ref name="pmid15274075">{{cite journal |vauthors=Ezzat S, Asa SL, Couldwell WT, Barr CE, Dodge WE, Vance ML, McCutcheon IE |title=The prevalence of pituitary adenomas: a systematic review |journal=Cancer |volume=101 |issue=3 |pages=613–9 |year=2004 |pmid=15274075 |doi=10.1002/cncr.20412 |url=http://onlinelibrary.wiley.com/doi/10.1002/cncr.20412/full}}</ref>
*A: 0 to 10 mm suprasellar extension occupying the suprasellar cistern.
| style="background: #F5F5F5; text-align: center;" |Microprolactinoma
 
| style="background: #F5F5F5;" | <10 mm diameter
*B: 10 mm  to 20 mm extension and elevation of the third [[ventricle]].
|-
 
| style="background: #F5F5F5; text-align: center;" |Macroprolactinoma
*C: 20 mm to 30 mm extension occupying the anterior of the third ventricle.
| style="background: #F5F5F5;" | >10 mm diameter
 
|-
*D: A larger than 30 mm extension, beyond the foramen of Monro, or Grade C with lateral extensions<ref>http://www.cancer.gov/types/pituitary/hp/pituitary-treatment-pdq#section/_3</ref>.
| rowspan="11" style="background: #DCDCDC; text-align: center;" |Classificatioin based on local invasion<ref name="urlPituitary Tumors Treatment (PDQ®)—Health Professional Version - National Cancer Institute">{{cite web |url=https://www.cancer.gov/types/pituitary/hp/pituitary-treatment-pdq#cit/section_3.3 |title=Pituitary Tumors Treatment (PDQ®)—Health Professional Version - National Cancer Institute |format= |work= |accessdate=}}</ref><ref name="pmid09436654">{{cite journal| author=Yeh PJ, Chen JW| title=Pituitary tumors: surgical and medical management. | journal=Surg Oncol | year= 1997 | volume= 6 | issue= 2 | pages= 67-92 | pmid=09436654 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9436654  }}</ref><ref>Hardy J: Transsphenoidal surgery of hypersecreting pituitary tumors. In: Kohler PO, Ross GT, eds.: Diagnosis and treatment of pituitary tumors: proceedings of a conference sponsored jointly by the National Institute of Child Health and Human Development and the National Cancer Institute,  January 15-17, 1973, Bethesda, Md. Amsterdam, The Netherlands: Excerpta medica, 1973, pp 179-98</ref>
| rowspan="5" style="background: #DCDCDC; text-align: center;" |Size and Invasion
| style="background: #F5F5F5; text-align: center;" |0
| style="background: #F5F5F5;" |Normal [[pituitary]] appearance
|-
| style="background: #F5F5F5; text-align: center;" |I
| style="background: #F5F5F5;" |Enclosed within the [[sella turcica]], microadenoma smaller than 10 mm
|-
| style="background: #F5F5F5; text-align: center;" |II
| style="background: #F5F5F5;" |Enclosed within the [[sella turcica]], macroadenoma 10 mm or larger
|-
| style="background: #F5F5F5; text-align: center;" |III
| style="background: #F5F5F5;" |Invasive, locally, into the [[sella turcica]]
|-
| style="background: #F5F5F5; text-align: center;" |IV
| style="background: #F5F5F5;" |Invasive, diffusely, into the [[sella turcica]]
|-
| rowspan="4" style="background: #DCDCDC; text-align: center;" |Grading scheme for suprasellar extensions
| style="background: #F5F5F5; text-align: center;" |A
| style="background: #F5F5F5;" |0 to 10 mm [[suprasellar]] extension occupying the [[suprasellar]]cistern
|-
| style="background: #F5F5F5; text-align: center;" |B
| style="background: #F5F5F5;" |10 mm  to 20 mm extension and elevation of the [[third ventricle]]
|-
| style="background: #F5F5F5; text-align: center;" |C
| style="background: #F5F5F5;" |20 mm to 30 mm extension occupying the [[anterior]] of the [[third ventricle]]
|-
| style="background: #F5F5F5; text-align: center;" |D
| style="background: #F5F5F5;" |A larger than 30 mm extension, beyond the [[foramen of Monro]], or Grade C with lateral extensions
|}


== References ==
== References ==
{{Reflist|2}}
{{Reflist|2}}
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Latest revision as of 23:49, 29 July 2020

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Faizan Sheraz, M.D. [2], Anmol Pitliya, M.B.B.S. M.D.[3]

Overview

Prolactinoma can be classified based upon either size or local invasion. Based on size, a prolactinoma can be classified as a microprolactinoma (<10 mm diameter) or macroprolactinoma (>10 mm diameter).

Classification

Prolactinoma may be classified based on either size or local invasion.

Classification of prolactinoma
Classification basis Type/Grade Criteria
Classification based on size[1] Microprolactinoma <10 mm diameter
Macroprolactinoma >10 mm diameter
Classificatioin based on local invasion[2][3][4] Size and Invasion 0 Normal pituitary appearance
I Enclosed within the sella turcica, microadenoma smaller than 10 mm
II Enclosed within the sella turcica, macroadenoma 10 mm or larger
III Invasive, locally, into the sella turcica
IV Invasive, diffusely, into the sella turcica
Grading scheme for suprasellar extensions A 0 to 10 mm suprasellar extension occupying the suprasellarcistern
B 10 mm to 20 mm extension and elevation of the third ventricle
C 20 mm to 30 mm extension occupying the anterior of the third ventricle
D A larger than 30 mm extension, beyond the foramen of Monro, or Grade C with lateral extensions

References

  1. ↑ Ezzat S, Asa SL, Couldwell WT, Barr CE, Dodge WE, Vance ML, McCutcheon IE (2004). "The prevalence of pituitary adenomas: a systematic review". Cancer. 101 (3): 613–9. doi:10.1002/cncr.20412. PMID 15274075.
  2. ↑ "Pituitary Tumors Treatment (PDQ®)—Health Professional Version - National Cancer Institute".
  3. ↑ Yeh PJ, Chen JW (1997). "Pituitary tumors: surgical and medical management". Surg Oncol. 6 (2): 67–92. PMID 09436654.
  4. ↑ Hardy J: Transsphenoidal surgery of hypersecreting pituitary tumors. In: Kohler PO, Ross GT, eds.: Diagnosis and treatment of pituitary tumors: proceedings of a conference sponsored jointly by the National Institute of Child Health and Human Development and the National Cancer Institute, January 15-17, 1973, Bethesda, Md. Amsterdam, The Netherlands: Excerpta medica, 1973, pp 179-98

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