Prolactinoma risk factors: Difference between revisions

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{{Prolactinoma}}
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==Overview==
==Overview==
[[Prolactinoma]] may occur as part of a hereditary disorder called multiple endocrine neoplasia type 1 (MEN 1), so patients with MEN 1 are at increased risk for prolactinoma. So patients with any of these syndromes are at increased risk for prolactinoma.
Conditions increasing the risk of [[prolactinoma]] inlude [[multiple endocrine neoplasia type 1]] ([[MEN 1]]), [[Carney complex]], [[McCune-Albright Syndrome]], familial isolated [[pituitary adenoma]], and MEN-1 like syndrome.


==Risk factors==
==Risk factors==
[[Prolactinoma]] may occur as part of a hereditary disorder called multiple endocrine neoplasia type 1 (MEN 1), so patients with MEN 1 are at increased risk for prolactinoma. A minority of tumors are associated with:
*Most commonly, [[prolactinomas]] are sporadic.
*Multiple endocrine neoplasia type I (MEN I)<ref>http://radiopaedia.org/articles/pituitary-adenoma</ref>
 
*Carney complex
*[[Prolactinoma]] may occur as part of:<ref name="pmid17613551">{{cite journal| author=Karhu A, Aaltonen LA| title=Susceptibility to pituitary neoplasia related to MEN-1, CDKN1B and AIP mutations: an update. | journal=Hum Mol Genet | year= 2007 | volume= 16 Spec No 1 | issue=  | pages= R73-9 | pmid=17613551 | doi=10.1093/hmg/ddm036 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17613551  }} </ref><ref name="pmid16411062">{{cite journal| author=Ciccarelli A, Daly AF, Beckers A| title=The epidemiology of prolactinomas. | journal=Pituitary | year= 2005 | volume= 8 | issue= 1 | pages= 3-6 | pmid=16411062 | doi=10.1007/s11102-005-5079-0 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16411062  }} </ref>
*McCune-Albright Syndrome
**[[Multiple endocrine neoplasia type 1]] ([[MEN 1]])
*MEN like syndrome ( CKDN1B loss of function)
**[[Carney complex]]
So patients with any of these syndromes are at increased risk for prolactinoma.
**[[McCune-Albright Syndrome]]
**Familial isolated [[pituitary adenoma]]
**[[MEN 1|MEN-1]] like syndrome
 
== References ==
== References ==
{{Reflist|2}}
{{Reflist|2}}
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Latest revision as of 23:50, 29 July 2020

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Anmol Pitliya, M.B.B.S. M.D.[2]

Overview

Conditions increasing the risk of prolactinoma inlude multiple endocrine neoplasia type 1 (MEN 1), Carney complex, McCune-Albright Syndrome, familial isolated pituitary adenoma, and MEN-1 like syndrome.

Risk factors

References

  1. Karhu A, Aaltonen LA (2007). "Susceptibility to pituitary neoplasia related to MEN-1, CDKN1B and AIP mutations: an update". Hum Mol Genet. 16 Spec No 1: R73–9. doi:10.1093/hmg/ddm036. PMID 17613551.
  2. Ciccarelli A, Daly AF, Beckers A (2005). "The epidemiology of prolactinomas". Pituitary. 8 (1): 3–6. doi:10.1007/s11102-005-5079-0. PMID 16411062.

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