Testicular cancer laboratory findings: Difference between revisions

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Latest revision as of 10:42, 28 May 2019

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Gertrude Djouka, M.D.[2], Shanshan Cen, M.D. [3]

Overview

An elevated concentration of blood tumor marker tests is diagnostic of testicular cancer.

Laboratory Tests

Tumor marker tests:^[1]^[2]

Tumor type	Tumor markers
Tumor type	Human chorionic gonadotropin (HCG)	Alpha-fetoprotein (AFP)	Lactate dehydrogenase (LDH)
Seminoma	↑	-	↑
Choriocarcinoma	↑↑	-	↑
Yolk sac tumor	-	↑	↑
Embryonal tumor	↑	↑	↑
Teratoma	-	↑	↑

Sex cord stromal testicular tumor

Leydig cell tumor^[3]

Estrogen or androgen is elevated
ACTH (adrenocorticothrophic hormone) is elevated

Sertoli cell tumor^[3]

Estrogen is elevated

References

↑ Milose JC, Filson CP, Weizer AZ, Hafez KS, Montgomery JS (December 2011). "Role of biochemical markers in testicular cancer: diagnosis, staging, and surveillance". Open Access J Urol. 4: 1–8. doi:10.2147/OAJU.S15063. PMC 3818947. PMID 24198649.
↑ Gilligan TD, Seidenfeld J, Basch EM, Einhorn LH, Fancher T, Smith DC, Stephenson AJ, Vaughn DJ, Cosby R, Hayes DF (July 2010). "American Society of Clinical Oncology Clinical Practice Guideline on uses of serum tumor markers in adult males with germ cell tumors". J. Clin. Oncol. 28 (20): 3388–404. doi:10.1200/JCO.2009.26.4481. PMID 20530278.
↑ ^3.0 ^3.1 Al-Agha OM, Axiotis CA (February 2007). "An in-depth look at Leydig cell tumor of the testis". Arch. Pathol. Lab. Med. 131 (2): 311–7. doi:10.1043/1543-2165(2007)131[311:AILALC]2.0.CO;2. PMID 17284120.

Template:WikiDoc Sources

[pmid24198649-1] Milose JC, Filson CP, Weizer AZ, Hafez KS, Montgomery JS (December 2011). "Role of biochemical markers in testicular cancer: diagnosis, staging, and surveillance". Open Access J Urol. 4: 1–8. doi:10.2147/OAJU.S15063. PMC 3818947. PMID 24198649.

[pmid20530278-2] Gilligan TD, Seidenfeld J, Basch EM, Einhorn LH, Fancher T, Smith DC, Stephenson AJ, Vaughn DJ, Cosby R, Hayes DF (July 2010). "American Society of Clinical Oncology Clinical Practice Guideline on uses of serum tumor markers in adult males with germ cell tumors". J. Clin. Oncol. 28 (20): 3388–404. doi:10.1200/JCO.2009.26.4481. PMID 20530278.

[pmid17284120-3] 3.0 ^3.1 Al-Agha OM, Axiotis CA (February 2007). "An in-depth look at Leydig cell tumor of the testis". Arch. Pathol. Lab. Med. 131 (2): 311–7. doi:10.1043/1543-2165(2007)131[311:AILALC]2.0.CO;2. PMID 17284120.

[1]

[2]

[3]

@@ Line 1: / Line 1: @@
 __NOTOC__
 {{Testicular cancer}}
-{{CMG}}
+{{CMG}}; {{AE}} {{G.D.}}, {{SC}}
 ==Overview==
-An elevated concentration of blood [[tumor marker]] tests is diagnostic of testicular cancer.
+An elevated concentration of [[blood]] [[tumor marker]] tests is [[diagnostic]] of testicular cancer.
 ==Laboratory Tests==
-'''Tumor marker tests'''<ref>Testicular cancer.2015 Canadian Cancer Society. http://www.cancer.ca/en/cancer-information/cancer-type/testicular/diagnosis/?region=ab#CBC Accessed on October, 13 2015 </ref>
+'''Tumor marker tests:'''<ref name="pmid24198649">{{cite journal |vauthors=Milose JC, Filson CP, Weizer AZ, Hafez KS, Montgomery JS |title=Role of biochemical markers in testicular cancer: diagnosis, staging, and surveillance |journal=Open Access J Urol |volume=4 |issue= |pages=1–8 |date=December 2011 |pmid=24198649 |pmc=3818947 |doi=10.2147/OAJU.S15063 |url=}}</ref><ref name="pmid20530278">{{cite journal |vauthors=Gilligan TD, Seidenfeld J, Basch EM, Einhorn LH, Fancher T, Smith DC, Stephenson AJ, Vaughn DJ, Cosby R, Hayes DF |title=American Society of Clinical Oncology Clinical Practice Guideline on uses of serum tumor markers in adult males with germ cell tumors |journal=J. Clin. Oncol. |volume=28 |issue=20 |pages=3388–404 |date=July 2010 |pmid=20530278 |doi=10.1200/JCO.2009.26.4481 |url=}}</ref>
-* [[Alpha-fetoprotein]] (AFP)
+{|
-* [[Human chorionic gonadotropin]] (HCG)
+! rowspan="2" align="center" style="background:#4479BA; color: #FFFFFF;" + |Tumor type
-* [[Lactate dehydrogenase]] (LDH)
+! colspan="3" align="center" style="background:#4479BA; color: #FFFFFF;" + |Tumor markers
+|-
+! align="center" style="background:#4479BA; color: #FFFFFF;" + |Human chorionic gonadotropin (HCG)
+! align="center" style="background:#4479BA; color: #FFFFFF;" + |Alpha-fetoprotein (AFP)
+! align="center" style="background:#4479BA; color: #FFFFFF;" + |Lactate dehydrogenase (LDH)
+|-
+! align="center" style="background:#DCDCDC;" + |Seminoma
+| align="center" style="background:#F5F5F5;" + |↑
+| align="center" style="background:#F5F5F5;" + | -
+| align="center" style="background:#F5F5F5;" + |↑
+|-
+! align="center" style="background:#DCDCDC;" + |Choriocarcinoma
+| align="center" style="background:#F5F5F5;" + |↑↑
+| align="center" style="background:#F5F5F5;" + | -
+| align="center" style="background:#F5F5F5;" + |↑
+|-
+! align="center" style="background:#DCDCDC;" + |Yolk sac tumor
+| align="center" style="background:#F5F5F5;" + | -
+| align="center" style="background:#F5F5F5;" + |↑
+| align="center" style="background:#F5F5F5;" + |↑
+|-
+! align="center" style="background:#DCDCDC;" + |Embryonal tumor
+| align="center" style="background:#F5F5F5;" + |↑
+| align="center" style="background:#F5F5F5;" + |↑
+| align="center" style="background:#F5F5F5;" + |↑
+|-
+! align="center" style="background:#DCDCDC;" + |Teratoma
+| align="center" style="background:#F5F5F5;" + | -
+| align="center" style="background:#F5F5F5;" + |↑
+| align="center" style="background:#F5F5F5;" + |↑
+|}
+==Sex cord stromal testicular tumor==
+Leydig cell tumor<ref name="pmid17284120">{{cite journal |vauthors=Al-Agha OM, Axiotis CA |title=An in-depth look at Leydig cell tumor of the testis |journal=Arch. Pathol. Lab. Med. |volume=131 |issue=2 |pages=311–7 |date=February 2007 |pmid=17284120 |doi=10.1043/1543-2165(2007)131[311:AILALC]2.0.CO;2 |url=}}</ref>
+*[[Estrogen]] or [[androgen]] is elevated
+*[[ACTH]] (adrenocorticothrophic hormone) is elevated
+Sertoli cell tumor<ref name="pmid17284120">{{cite journal |vauthors=Al-Agha OM, Axiotis CA |title=An in-depth look at Leydig cell tumor of the testis |journal=Arch. Pathol. Lab. Med. |volume=131 |issue=2 |pages=311–7 |date=February 2007 |pmid=17284120 |doi=10.1043/1543-2165(2007)131[311:AILALC]2.0.CO;2 |url=}}</ref>
+*[[Estrogen]] is elevated
 ==References==
@@ Line 20: / Line 57: @@
 [[Category:Andrology]]
 [[Category:Types of cancer]]
+ [[Category:Up-To-Date]]
+[[Category:Oncology]]
+[[Category:Medicine]]
+[[Category:Urology]]

Testicular cancer laboratory findings: Difference between revisions

Latest revision as of 10:42, 28 May 2019

Overview

Laboratory Tests

Sex cord stromal testicular tumor

References

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