Uveal melanoma history and symptoms: Difference between revisions

Jump to navigation Jump to search
VisualWikitext
No edit summary
m (Bot: Removing from Primary care)
 
(24 intermediate revisions by 4 users not shown)
Line 3: Line 3:
{{CMG}}{{AE}}{{Simrat}}
{{CMG}}{{AE}}{{Simrat}}
==Overview==
==Overview==
Symptoms of uveal melanoma include eye pain, eye redness, loss of peripheral vision, poor or blurry vision in one eye, a dark spot on the iris, seeing flashing lights, floaters, and symptoms of glaucoma.
A positive [[History and Physical examination|history]] of pre-existing [[iris]] [[nevus]] which increased in size, [[eye pain]], [[Vision loss|visual loss]], [[blurred vision]], [[Floater|floaters]], age between 50_70 years old, [[male]] gender, white [[race]], [[pregnancy]], [[Immune system disorder|impaired immune system]], light colored-irides, [[sunlight]] exposure, [[trauma]], and [[Fluorescence|fluorescent]] lighting exposure is suggestive of uveal melanoma. The most common [[Symptom|symptoms]] of uveal melanoma include ,[[eye pain]], [[blurred vision]], [[eye]] redness, loss of [[peripheral vision]], poor or [[blurry vision]] in one [[eye]], a dark spot on the [[iris]], seeing flashing lights, and [[Floater|floaters]].
==History==
==History and Symptoms==
==Symptoms==
 
Clinical presentation depends on the location. When the tumour is located on the iris then it may be apparent to the patient or friends and family as a brown nodule. Choroidal or ciliary body tumours are only identified incidentally on fundoscopy or as a result of retinal detachment or advanced disease.
*[[Symptoms]] of uveal melanoma include [[eye pain]], [[blurred vision]], [[eye]] redness, loss of [[peripheral vision]], poor or [[blurry vision]] in one [[eye]], a dark spot on  the [[iris]], seeing flashing lights, and [[floaters]].
Uveal melanoma usually does not cause symptoms. Many cases of uveal melanoma are found during routine eye examination. If symptoms are present they may include:
 
*Eye pain
=== History ===
*Eye redness
Patients with uveal melanoma may have a positive history of:<ref name="EganSeddon1988">{{cite journal|last1=Egan|first1=Kathleen M.|last2=Seddon|first2=Johanna M.|last3=Glynn|first3=Robert J.|last4=Gragoudas|first4=Evangelos S.|last5=Albert|first5=Daniel M.|title=Epidemiologic aspects of uveal melanoma|journal=Survey of Ophthalmology|volume=32|issue=4|year=1988|pages=239–251|issn=00396257|doi=10.1016/0039-6257(88)90173-7}}</ref><ref name="NCI">Uveal melanoma. National Cancer Institute(2015) http://www.cancer.gov/types/eye/hp/intraocular-melanoma-treatment-pdq Accessed on October 24 2015</ref><ref name="vanKoopmans2013">{{cite journal|last1=van|first1=J.G.M.|last2=Koopmans|first2=A.E.|last3=Verdijk|first3=R.M.|last4=Naus|first4=N.C.|last5=de|first5=A.|last6=Kilic|first6=E.|title=Diagnosis, Histopathologic and Genetic Classification of Uveal Melanoma|year=2013|doi=10.5772/53631}}</ref><ref name="Reese1944">{{cite journal|last1=Reese|first1=Algernon B.|title=Pigment Freckles of the Iris (Benign Melanomas): Their Significance in Relation to Malignant Melanoma of the Uvea⋆|journal=American Journal of Ophthalmology|volume=27|issue=3|year=1944|pages=217–226|issn=00029394|doi=10.1016/S0002-9394(44)91382-6}}</ref><ref name="Siegel1963">{{cite journal|last1=Siegel|first1=Ralph|title=Malignant Ocular Melanoma During Pregnancy|journal=JAMA: The Journal of the American Medical Association|volume=185|issue=6|year=1963|pages=542|issn=0098-7484|doi=10.1001/jama.1963.03060060140028}}</ref><ref name="FisherKripke1982">{{cite journal|last1=Fisher|first1=M.|last2=Kripke|first2=M.|title=Suppressor T lymphocytes control the development of primary skin cancers in ultraviolet-irradiated mice|journal=Science|volume=216|issue=4550|year=1982|pages=1133–1134|issn=0036-8075|doi=10.1126/science.6210958}}</ref><ref>{{cite journal|title=Risk Factors for Ocular Melanoma: Western Canada Melanoma Study<xref ref-type="fn" rid="FN1">2</xref><xref ref-type="fn" rid="FN2">3</xref>|journal=JNCI: Journal of the National Cancer Institute|year=1985|issn=1460-2105|doi=10.1093/jnci/74.4.775}}</ref><ref name="TuckerShields1985">{{cite journal|last1=Tucker|first1=Margaret A.|last2=Shields|first2=Jerry A.|last3=Hartge|first3=Patricia|last4=Augsburger|first4=James|last5=Hoover|first5=Robert N.|last6=Fraumeni|first6=Joseph F.|title=Sunlight Exposure as Risk Factor for Intraocular Malignant Melanoma|journal=New England Journal of Medicine|volume=313|issue=13|year=1985|pages=789–792|issn=0028-4793|doi=10.1056/NEJM198509263131305}}</ref><ref name="BabaBlumenkranz1986">{{cite journal|last1=Baba|first1=F. E.|last2=Blumenkranz|first2=M.|title=Malignant Melanoma at the Site of Penetrating Ocular Trauma|journal=Archives of Ophthalmology|volume=104|issue=3|year=1986|pages=405–409|issn=0003-9950|doi=10.1001/archopht.1986.01050150105038}}</ref><ref name="BeralShaw1982">{{cite journal|last1=Beral|first1=Valerie|last2=Shaw|first2=Helen|last3=Evans|first3=Susan|last4=Milton|first4=Gerald|title=MALIGNANT MELANOMA AND EXPOSURE TO FLUORESCENT LIGHTING AT WORK|journal=The Lancet|volume=320|issue=8293|year=1982|pages=290–293|issn=01406736|doi=10.1016/S0140-6736(82)90270-7}}</ref>
*Loss of peripheral vision
 
*Poor or blurry vision in one eye
* Pre-existing [[iris]] [[nevus]] which increased in size
*A dark spot on the iris
*[[Eye pain]]
*[[Vision loss|Visual loss]]
*[[Blurred vision]]
*[[Floaters]]
*[[Ageing|Age]] between 50_70 years old
*[[Male]] gender
* white [[Race for Life|race]]
*[[Pregnancy]]
*[[Immune system disorder|Impaired immune system]]
* light colored-irides
*[[Sunlight]] exposure
*[[Trauma]]
*[[Fluorescent]] lighting exposure
 
===Common Symptoms===
Common [[Symptom|symptoms]] of uveal melanoma include:<ref name="radio">Retinoblastoma. Radiopedia(2015) http://radiopaedia.org/articles/primary-uveal-malignant-melanoma Accessed on October 21, 2015</ref><ref name="pmid23826405">{{cite journal| author=Jovanovic P, Mihajlovic M, Djordjevic-Jocic J, Vlajkovic S, Cekic S, Stefanovic V| title=Ocular melanoma: an overview of the current status. | journal=Int J Clin Exp Pathol | year= 2013 | volume= 6 | issue= 7 | pages= 1230-44 | pmid=23826405 | doi= | pmc=PMC3693189 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23826405  }} </ref>
 
*[[Eye pain]]
*[[Blurred vision]]
*[[Eye]] redness
*Loss of [[peripheral vision]]
*Poor or [[blurry vision]] in one [[eye]]
*A dark spot on the [[iris]]
*Seeing flashing lights
*Seeing flashing lights
*Floaters
*[[Floaters]]
*Symptoms of glaucoma
 
**Severe headache
=== Less Common Symptoms ===
**Nausea and vomiting
Less common [[Symptoms and Signs|symptoms]] of uveal melanoma include:
**Blurred vision
 
**Halos around lights
*Severe [[headache]]
*[[Nausea]] and [[vomiting]]
*Halos around lights
== References ==  
== References ==  
{{Reflist|2}}
{{Reflist|2}}
​
[[Category:Medicine]]
[[Category:Oncology]]
[[Category:Up-To-Date]]
[[Category:Surgery]]

Latest revision as of 00:37, 30 July 2020

Uveal melanoma Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Uveal melanoma from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Study of Choice

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

X Ray

Echocardiography and Ultrasound

CT

MRI

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Uveal melanoma history and symptoms On the Web

Most recent articles

cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Uveal melanoma history and symptoms

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Uveal melanoma history and symptoms

CDC on Uveal melanoma history and symptoms

Uveal melanoma history and symptoms in the news

Blogs on Uveal melanoma history and symptoms

to Hospitals Treating Uveal melanoma

Risk calculators and risk factors for Uveal melanoma history and symptoms

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Simrat Sarai, M.D. [2]

Overview

A positive history of pre-existing iris nevus which increased in size, eye pain, visual loss, blurred vision, floaters, age between 50_70 years old, male gender, white race, pregnancy, impaired immune system, light colored-irides, sunlight exposure, trauma, and fluorescent lighting exposure is suggestive of uveal melanoma. The most common symptoms of uveal melanoma include ,eye pain, blurred vision, eye redness, loss of peripheral vision, poor or blurry vision in one eye, a dark spot on the iris, seeing flashing lights, and floaters.

History and Symptoms

History

Patients with uveal melanoma may have a positive history of:[1][2][3][4][5][6][7][8][9][10]

Common Symptoms

Common symptoms of uveal melanoma include:[11][12]

Less Common Symptoms

Less common symptoms of uveal melanoma include:

References

  1. ↑ Egan, Kathleen M.; Seddon, Johanna M.; Glynn, Robert J.; Gragoudas, Evangelos S.; Albert, Daniel M. (1988). "Epidemiologic aspects of uveal melanoma". Survey of Ophthalmology. 32 (4): 239–251. doi:10.1016/0039-6257(88)90173-7. ISSN 0039-6257.
  2. ↑ Uveal melanoma. National Cancer Institute(2015) http://www.cancer.gov/types/eye/hp/intraocular-melanoma-treatment-pdq Accessed on October 24 2015
  3. ↑ van, J.G.M.; Koopmans, A.E.; Verdijk, R.M.; Naus, N.C.; de, A.; Kilic, E. (2013). "Diagnosis, Histopathologic and Genetic Classification of Uveal Melanoma". doi:10.5772/53631.
  4. ↑ Reese, Algernon B. (1944). "Pigment Freckles of the Iris (Benign Melanomas): Their Significance in Relation to Malignant Melanoma of the Uvea⋆". American Journal of Ophthalmology. 27 (3): 217–226. doi:10.1016/S0002-9394(44)91382-6. ISSN 0002-9394.
  5. ↑ Siegel, Ralph (1963). "Malignant Ocular Melanoma During Pregnancy". JAMA: The Journal of the American Medical Association. 185 (6): 542. doi:10.1001/jama.1963.03060060140028. ISSN 0098-7484.
  6. ↑ Fisher, M.; Kripke, M. (1982). "Suppressor T lymphocytes control the development of primary skin cancers in ultraviolet-irradiated mice". Science. 216 (4550): 1133–1134. doi:10.1126/science.6210958. ISSN 0036-8075.
  7. ↑ "Risk Factors for Ocular Melanoma: Western Canada Melanoma Study<xref ref-type="fn" rid="FN1">2</xref><xref ref-type="fn" rid="FN2">3</xref>". JNCI: Journal of the National Cancer Institute. 1985. doi:10.1093/jnci/74.4.775. ISSN 1460-2105.
  8. ↑ Tucker, Margaret A.; Shields, Jerry A.; Hartge, Patricia; Augsburger, James; Hoover, Robert N.; Fraumeni, Joseph F. (1985). "Sunlight Exposure as Risk Factor for Intraocular Malignant Melanoma". New England Journal of Medicine. 313 (13): 789–792. doi:10.1056/NEJM198509263131305. ISSN 0028-4793.
  9. ↑ Baba, F. E.; Blumenkranz, M. (1986). "Malignant Melanoma at the Site of Penetrating Ocular Trauma". Archives of Ophthalmology. 104 (3): 405–409. doi:10.1001/archopht.1986.01050150105038. ISSN 0003-9950.
  10. ↑ Beral, Valerie; Shaw, Helen; Evans, Susan; Milton, Gerald (1982). "MALIGNANT MELANOMA AND EXPOSURE TO FLUORESCENT LIGHTING AT WORK". The Lancet. 320 (8293): 290–293. doi:10.1016/S0140-6736(82)90270-7. ISSN 0140-6736.
  11. ↑ Retinoblastoma. Radiopedia(2015) http://radiopaedia.org/articles/primary-uveal-malignant-melanoma Accessed on October 21, 2015
  12. ↑ Jovanovic P, Mihajlovic M, Djordjevic-Jocic J, Vlajkovic S, Cekic S, Stefanovic V (2013). "Ocular melanoma: an overview of the current status". Int J Clin Exp Pathol. 6 (7): 1230–44. PMC 3693189. PMID 23826405.

​

Retrieved from "https://www.wikidoc.org/index.php?title=Uveal_melanoma_history_and_symptoms&oldid=1644411"