Hepatoblastoma risk factors: Difference between revisions

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Latest revision as of 01:58, 27 November 2017

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Nawal Muazam M.D.[2]

Overview

Common risk factors in the development of hepatoblastoma are Aicardi syndrome, Beckwith-Wiedemann syndrome, familial adenomatous polyposis, low birth weight infants, and glycogen storage diseases.^[1]

Risk Factors

The table below lists risk factors for hepatoblastoma:^[1]


Associated Disorder	Clinical findings

Aicardi syndrome	Agenesis of the corpus callosum, chorioretinal lacunae, and infantile spasms, with a characteristic facies
Beckwith-Wiedemann syndrome	Hemihypertrophy, hemihyperplasia
Familial adenomatous polyposis	Adenoma, hepatoblastoma
Glycogen storage diseases I–IV	Symptoms vary by individual disorder
Low birth weight infants	Preterm and small-for-gestation-age neonates
Simpson-Golabi-Behmel syndrome	Macroglossia, macrosomia, renal and skeletal abnormalities, and increased risk of Wilms tumor
Trisomy 18, other trisomies	Trisomy 18: Microcephaly and micrognathia, clenched fists with overlapping fingers, and failure to thrive

References

↑ ^1.0 ^1.1 Risk factors. National Cancer Institute 2015. http://www.cancer.gov/types/liver/hp/child-liver-treatment-pdq#link/_570_toc. Accessed on October 28, 2015

Template:WikiDoc Sources

[risk-1] 1.0 ^1.1 Risk factors. National Cancer Institute 2015. http://www.cancer.gov/types/liver/hp/child-liver-treatment-pdq#link/_570_toc. Accessed on October 28, 2015

[1]

@@ Line 3: / Line 3: @@
 {{CMG}};{{AE}} {{NM}}
 ==Overview==
+Common risk factors in the development of hepatoblastoma are [[Aicardi syndrome]], [[Beckwith-Wiedemann syndrome]], [[familial adenomatous polyposis]], [[low birth weight|low birth weight infants]], and [[glycogen storage diseases]].<ref name=risk>Risk factors. National Cancer Institute 2015. http://www.cancer.gov/types/liver/hp/child-liver-treatment-pdq#link/_570_toc. Accessed on October 28, 2015</ref>
 ==Risk Factors==
-Risk factors for hepatoblastoma including the following:
+The table below lists risk factors for hepatoblastoma:<ref name=risk>Risk factors. National Cancer Institute 2015. http://www.cancer.gov/types/liver/hp/child-liver-treatment-pdq#link/_570_toc. Accessed on October 28, 2015</ref>
-* Being male.
+{| style="border: 0px; font-size: 90%; margin: 3px; width: 1000px"
-* Having [[familial adenomatous polyposis]] (FAP).
+|valign=top|
-* Having [[Beckwith-Wiedemann syndrome]].
+|+
-* Having had a very low weight at birth.
+! style="background: #4479BA; width: 250px; color: #FFFFFF;"|'''Associated Disorder'''
+! style="background: #4479BA; width: 600px; color: #FFFFFF;"|'''Clinical findings'''
+|-
+| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center | '''[[Aicardi syndrome]]'''|| style="padding: 5px 5px; background: #F5F5F5;" |
+:* Agenesis of the corpus callosum, chorioretinal lacunae, and [[infantile spasms]], with a characteristic facies
+|-
+| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center | '''[[Beckwith-Wiedemann syndrome]]'''|| style="padding: 5px 5px; background: #F5F5F5;"|
+:* [[Hemihypertrophy]], hemihyperplasia
+|-
+| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center | '''[[Familial adenomatous polyposis]]'''|| style="padding: 5px 5px; background: #F5F5F5;"|
+:*Adenoma, hepatoblastoma
+|-
+| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center | '''[[Glycogen storage diseases]] I–IV '''|| style="padding: 5px 5px; background: #F5F5F5;" |
+:*Symptoms vary by individual disorder
+|-
+| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center | '''[[low birth weight|Low birth weight infants]]'''|| style="padding: 5px 5px; background: #F5F5F5;" |
+:*Preterm and small-for-gestation-age neonates
+|-
+| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center | '''[[Simpson-Golabi-Behmel syndrome]]'''|| style="padding: 5px 5px; background: #F5F5F5;"|
+:*[[Macroglossia]], [[macrosomia]], renal and skeletal abnormalities, and increased risk of [[Wilms tumor]]
+|-
+|style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center | '''[[Trisomy 18]], other trisomies'''|| style="padding: 5px 5px; background: #F5F5F5;" |
+:*[[Trisomy 18]]: [[Microcephaly]] and [[micrognathia]], clenched fists with overlapping fingers, and [[failure to thrive]]
+|}
 ==References==
-{{reflist|2}}
+{{reflist|1}}
 [[Category:Disease]]
@@ Line 21: / Line 59: @@
 {{WikiDoc Help Menu}}
 {{WikiDoc Sources}}
+ [[Category:Up-To-Date]]
+[[Category:Oncology]]
+[[Category:Medicine]]
+[[Category:Gastroenterology]]
+[[Category:Surgery]]
+[[Category:Hepatology]]

Hepatoblastoma risk factors: Difference between revisions

Latest revision as of 01:58, 27 November 2017

Overview

Risk Factors

References

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