Malignant peripheral nerve sheath tumor history and symptoms: Difference between revisions
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{{Malignant peripheral nerve sheath tumor}} | {{Malignant peripheral nerve sheath tumor}} | ||
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==Overview== | ==Overview== | ||
Symptoms of malignant peripheral nerve sheath tumor include [[peripheral edema]], difficulty in moving the extremity, [[pain]], and [[numbness]].<ref name="pmid16029330">{{cite journal| author=Valeyrie-Allanore L, Ismaïli N, Bastuji-Garin S, Zeller J, Wechsler J, Revuz J et al.| title=Symptoms associated with malignancy of peripheral nerve sheath tumours: a retrospective study of 69 patients with neurofibromatosis 1. | journal=Br J Dermatol | year= 2005 | volume= 153 | issue= 1 | pages= 79-82 | pmid=16029330 | doi=10.1111/j.1365-2133.2005.06558.x | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16029330 }} </ref> | Patients present with a rapidly enlarging mass that may be painful or cause local neurological symptoms such as weakness or paresthesias. The development of new, worsening, or persistent pain in the neurofibroma of a patient with NF1 is an important symptom that should always be conscientiously evaluated, even if there was already pre-existing chronic discomfort from the lesion.The most common sites of involvement include the nerve roots and bundles in the extremities and pelvis, particularly the sciatic nerve. Symptoms of malignant peripheral nerve sheath tumor include [[peripheral edema]], difficulty in moving the affected extremity, [[pain]], and [[numbness]].<ref name="pmid16029330">{{cite journal| author=Valeyrie-Allanore L, Ismaïli N, Bastuji-Garin S, Zeller J, Wechsler J, Revuz J et al.| title=Symptoms associated with malignancy of peripheral nerve sheath tumours: a retrospective study of 69 patients with neurofibromatosis 1. | journal=Br J Dermatol | year= 2005 | volume= 153 | issue= 1 | pages= 79-82 | pmid=16029330 | doi=10.1111/j.1365-2133.2005.06558.x | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16029330 }} </ref> | ||
==Symptoms== | ==Symptoms== | ||
Symptoms of malignant peripheral nerve sheath tumor include:<ref name="pmid16029330">{{cite journal| author=Valeyrie-Allanore L, Ismaïli N, Bastuji-Garin S, Zeller J, Wechsler J, Revuz J et al.| title=Symptoms associated with malignancy of peripheral nerve sheath tumours: a retrospective study of 69 patients with neurofibromatosis 1. | journal=Br J Dermatol | year= 2005 | volume= 153 | issue= 1 | pages= 79-82 | pmid=16029330 | doi=10.1111/j.1365-2133.2005.06558.x | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16029330 }} </ref> | Symptoms of malignant peripheral nerve sheath tumor include:<ref name="pmid16029330">{{cite journal| author=Valeyrie-Allanore L, Ismaïli N, Bastuji-Garin S, Zeller J, Wechsler J, Revuz J et al.| title=Symptoms associated with malignancy of peripheral nerve sheath tumours: a retrospective study of 69 patients with neurofibromatosis 1. | journal=Br J Dermatol | year= 2005 | volume= 153 | issue= 1 | pages= 79-82 | pmid=16029330 | doi=10.1111/j.1365-2133.2005.06558.x | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16029330 }} </ref> | ||
* [[Peripheral edema]] | * [[Peripheral edema]] | ||
* Difficulty in moving the extremity | * Difficulty in moving the affected extremity | ||
* [[Pain]] | * [[Pain]] | ||
* [[Numbness]] | * [[Numbness]] | ||
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[[Category:Types of cancer]] | [[Category:Types of cancer]] | ||
[[Category:Neurology]] | [[Category:Neurology]] | ||
[[Category:Up-To-Date]] | |||
[[Category:Oncology]] | |||
[[Category:Medicine]] | |||
[[Category:Neurology]] | |||
[[Category:Neurosurgery]] | |||
Latest revision as of 13:43, 26 August 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Marjan Khan M.B.B.S.[2]
Overview
Patients present with a rapidly enlarging mass that may be painful or cause local neurological symptoms such as weakness or paresthesias. The development of new, worsening, or persistent pain in the neurofibroma of a patient with NF1 is an important symptom that should always be conscientiously evaluated, even if there was already pre-existing chronic discomfort from the lesion.The most common sites of involvement include the nerve roots and bundles in the extremities and pelvis, particularly the sciatic nerve. Symptoms of malignant peripheral nerve sheath tumor include peripheral edema, difficulty in moving the affected extremity, pain, and numbness.[1]
Symptoms
Symptoms of malignant peripheral nerve sheath tumor include:[1]
- Peripheral edema
- Difficulty in moving the affected extremity
- Pain
- Numbness
- Burning
References
- ↑ 1.0 1.1 Valeyrie-Allanore L, Ismaïli N, Bastuji-Garin S, Zeller J, Wechsler J, Revuz J; et al. (2005). "Symptoms associated with malignancy of peripheral nerve sheath tumours: a retrospective study of 69 patients with neurofibromatosis 1". Br J Dermatol. 153 (1): 79–82. doi:10.1111/j.1365-2133.2005.06558.x. PMID 16029330.