Malignant fibrous histiocytoma pathophysiology: Difference between revisions
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==Overview== | ==Overview== | ||
On microscopic histopathological analysis, storiform pattern, nuclear polymorphism, and atypical mitoses are characteristic findings of malignant fibrous histiocytoma. | |||
==Pathophysiology== | ==Pathophysiology== | ||
==Pathogenesis== | ==Pathogenesis== | ||
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==Gross Pathology== | ==Gross Pathology== | ||
==Microscopic Pathology== | ==Microscopic Pathology== | ||
On microscopic histopathological analysis, findings of malignant fibrous histiocytoma include:<ref name=Librepathology>Microscopic features of malignant fibrous histiocytoma. Librepathology (2015). http://librepathology.org/wiki/index.php/Pleomorphic_undifferentiated_sarcoma. Accessed on December 18, 2015</ref> | |||
*Storiform pattern | |||
*Marked nuclear pleomorphism | |||
*Variation is nuclear size, nuclear shape and nuclear staining (especially hyperchromasia) | |||
*Mitoses - abundant; atypical mitoses common | |||
*Necrosis (common) | |||
*Mix of spindle cells and epithelioid cells | |||
*Deep to skin | |||
===Gallery=== | ===Gallery=== | ||
==Immunohistochemistry== | ==Immunohistochemistry== | ||
==References== | ==References== | ||
{{reflist| | {{reflist|1}} | ||
{{WH}} | {{WH}} | ||
Latest revision as of 14:25, 21 December 2015
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Malignant fibrous histiocytoma Microchapters |
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Differentiating Malignant Fibrous Histiocytoma from other Diseases |
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Diagnosis |
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Treatment |
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Case Studies |
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Malignant fibrous histiocytoma pathophysiology On the Web |
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American Roentgen Ray Society Images of Malignant fibrous histiocytoma pathophysiology |
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Directions to Hospitals Treating Malignant fibrous histiocytoma |
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Risk calculators and risk factors for Malignant fibrous histiocytoma pathophysiology |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Nawal Muazam M.D.[2]
Overview
On microscopic histopathological analysis, storiform pattern, nuclear polymorphism, and atypical mitoses are characteristic findings of malignant fibrous histiocytoma.
Pathophysiology
Pathogenesis
Genetics
Associated conditions
Gross Pathology
Microscopic Pathology
On microscopic histopathological analysis, findings of malignant fibrous histiocytoma include:[1]
- Storiform pattern
- Marked nuclear pleomorphism
- Variation is nuclear size, nuclear shape and nuclear staining (especially hyperchromasia)
- Mitoses - abundant; atypical mitoses common
- Necrosis (common)
- Mix of spindle cells and epithelioid cells
- Deep to skin
Gallery
Immunohistochemistry
References
- ↑ Microscopic features of malignant fibrous histiocytoma. Librepathology (2015). http://librepathology.org/wiki/index.php/Pleomorphic_undifferentiated_sarcoma. Accessed on December 18, 2015