Atypical teratoid rhabdoid tumor other diagnostic studies: Difference between revisions
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==Overview== | ==Overview== | ||
Other diagnostic studies for atypical teratoid rhabdoid tumor include [[biopsy]] (definitive diagnostic test), fluorescence in situ hybridization (abnormalities of [[22q11.2 deletion syndrome|chromosome 22q11.2]]), and immunohistochemistry (loss of INI-1 staining in the neoplastic cells). | Other [[Diagnosis|diagnostic]] studies for atypical teratoid rhabdoid tumor include [[biopsy]] (definitive [[Diagnosis|diagnostic]] [[test]]), [[fluorescence in situ hybridization]] (abnormalities of [[22q11.2 deletion syndrome|chromosome 22q11.2]]), and [[immunohistochemistry]] (loss of INI-1 [[staining]] in the [[Cancer|neoplastic]] [[Cell (biology)|cells]]). | ||
==Other Diagnostic Studies== | ==Other Diagnostic Studies== | ||
==Biopsy== | ===Biopsy=== | ||
[[Biopsy]] is performed for definitive diagnosis of atypical teratoid rhabdoid tumor.<ref name=biopsyatrt1>Diagnostic evaluation of atypical teratoid rhabdoid tumor. National Cancer Institute 2015. http://www.cancer.gov/types/brain/hp/child-cns-atrt-treatment-pdq#link/_113_toc. Accessed on December 16, 2015</ref> | [[Biopsy]] is performed for the definitive [[diagnosis]] of atypical teratoid rhabdoid tumor.<ref name="biopsyatrt1">Diagnostic evaluation of atypical teratoid rhabdoid tumor. National Cancer Institute 2015. http://www.cancer.gov/types/brain/hp/child-cns-atrt-treatment-pdq#link/_113_toc. Accessed on December 16, 2015</ref> | ||
==Fluorescent In Situ Hybridization== | ===Fluorescent In Situ Hybridization=== | ||
Fluorescence in situ hybridization demonstrates abnormalities of [[22q11.2 deletion syndrome|chromosome 22q11.2]]. | [[Fluorescence in situ hybridization]] demonstrates abnormalities of [[22q11.2 deletion syndrome|chromosome 22q11.2]]. | ||
==Immunohistochemistry== | ===Immunohistochemistry=== | ||
Immunohistochemistry studies reveal the loss of INI-1 staining in the neoplastic cells confirming the diagnosis of | [[Immunohistochemistry]] studies reveal the loss of INI-1 [[staining]] in the [[Cancer|neoplastic]] [[Cell (biology)|cells]] confirming the [[diagnosis]] of atypical teratoid rhabdoid tumor.<ref name="UdakaShayan2013">{{cite journal|last1=Udaka|first1=Y. T.|last2=Shayan|first2=K.|last3=Chuang|first3=N. A.|last4=Crawford|first4=J. R.|title=Atypical Presentation of Atypical Teratoid Rhabdoid Tumor in a Child|journal=Case Reports in Oncological Medicine|volume=2013|year=2013|pages=1–4|issn=2090-6706|doi=10.1155/2013/815923}}</ref> | ||
==References== | ==References== |
Latest revision as of 21:06, 16 May 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]
Overview
Other diagnostic studies for atypical teratoid rhabdoid tumor include biopsy (definitive diagnostic test), fluorescence in situ hybridization (abnormalities of chromosome 22q11.2), and immunohistochemistry (loss of INI-1 staining in the neoplastic cells).
Other Diagnostic Studies
Biopsy
Biopsy is performed for the definitive diagnosis of atypical teratoid rhabdoid tumor.[1]
Fluorescent In Situ Hybridization
Fluorescence in situ hybridization demonstrates abnormalities of chromosome 22q11.2.
Immunohistochemistry
Immunohistochemistry studies reveal the loss of INI-1 staining in the neoplastic cells confirming the diagnosis of atypical teratoid rhabdoid tumor.[2]
References
- ↑ Diagnostic evaluation of atypical teratoid rhabdoid tumor. National Cancer Institute 2015. http://www.cancer.gov/types/brain/hp/child-cns-atrt-treatment-pdq#link/_113_toc. Accessed on December 16, 2015
- ↑ Udaka, Y. T.; Shayan, K.; Chuang, N. A.; Crawford, J. R. (2013). "Atypical Presentation of Atypical Teratoid Rhabdoid Tumor in a Child". Case Reports in Oncological Medicine. 2013: 1–4. doi:10.1155/2013/815923. ISSN 2090-6706.